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Biomedical subjects

R T Sataloff

Publications and source records attributed to R T Sataloff.

At least 127 records · Page 7Linked to original sources

Genetics of the voice.

Substantial advances have led to the evolution of voice as the newest subspecialty of otolaryngology. Nevertheless, little is known about the genetics of voice. Genetic research is needed to further elucidate the relationship between vocal tract structure (including ultrastructure) and function, mechanisms of voice dysfunction, and transmission of normal and abnormal voice characteristics.

Humans↗

G. Paul Moore Lecture. Rational thought: the impact of voice science upon voice care.

Recent evolution in scientific knowledge and technology has led to monumental improvement in the standard of care for patients with voice disorders. New concepts in anatomy, physiology, measurement, and analysis have provided voice care professionals with not merely better understanding, but moreover an extensive vocabulary with which to think about voice function and dysfunction. Previously, we had to depend too much upon anecdote and "the art of medicine." Thanks to scientific advances, we now have the tools we need for rational thought about the human voice. This is the fundamental change responsible for recent great advances in voice care.

Humans↗

Laryngeal mini-microflap: a new technique and reassessment of the microflap saga.

Vocal fold surgical technique has advanced substantially because of increased knowledge regarding anatomy and physiology of phonation and because of technological improvements. However, many new techniques have been based on anecdote and "common sense," largely because there is no good experimental model for vocal fold surgery since the human is the only species with a vocal ligament. Consequently, our earlier pronouncements require careful reexamination especially as new research adds to our fund of knowledge. Review of the principles and results of laryngeal microflap surgery suggests that there may be important shortcomings in the technique. A new mini-microflap technique appears better, as does limited mucosal resection. This is a preliminary report, and further investigation is needed.

Humans↗

Gastroesophageal reflux laryngitis resistant to omeprazole therapy.

Gastroesophageal reflux disease (GERD) is known to cause a variety of symptoms that lead a patient to seek otolaryngologic care. New advances in the treatment of GERD have enabled otolaryngologists to eliminate most of the signs and symptoms caused by acid reflux. Omeprazole, the most recent pharmacologic advancement, has been reported to be universally successful in controlling acid release from the stomach of patients with GERD. This report describes a series of patients with GERD for whom high-dose omeprazole therapy was not successful in completely reducing gastric acid levels of GERD symptomatology.

Adult↗

Vocal disorders and the professional voice user: the allergist's role.

BACKGROUND: As the modulating and power source for the voice, the upper and lower respiratory tracts play a key role in management of voice production. Allergic respiratory disease can impair vocalization, which can be a particular problem in the professional voice user. OBJECTIVE: The goal of this review is to facilitate the evaluation and management of professional voice users who have allergic respiratory problems contributing to their vocal dysfunction. This article discusses the anatomy and physiology of voice production, laryngeal pathology, and special diagnostic and therapeutic considerations relative to the allergist's role in treatment of these patients. METHODS: Mechanisms of voice production are reviewed, as well as common laryngeal pathology effecting voice production. Allergic respiratory diseases are summarized, with particular attention to those aspects of management that are altered in professional voice users. RESULTS: Professional voice users require modification in their management to optimize vocal function and minimize abnormalities of the vocal tract. This includes avoidance of medications that produce drying of the airway, as well as avoidance of inhaled corticosteroids. Subtle changes in respiratory function, which may be of no consequence to other individuals, may adversely affect performance ability, and need aggressive management. Allergen immunotherapy, because of its lack of adverse effects on the vocal apparatus, is particularly well suited for treatment of professional voice users. CONCLUSIONS: Allergists have an important role to play in management of the professional voice user. With careful attention to the unique requirements of these highly trained individuals, the allergist can enhance their performance ability while minimizing side effects from treatment.

Humans↗

Intracranial facial neuromas: total tumor removal with facial nerve preservation: a new surgical technique.

Neuromas of the facial nerve are uncommon tumors. The majority of cases involve the intratemporal and parotid areas. Since their description in 1930, there have been only 26 cases of intracranial facial neuroma reported in the world literature. Of these, 19 involved the middle cranial fossa, and only seven tumors extended into or originated in the posterior cranial fossa. In this location, the seventh nerve is surrounded by a very delicate and thin arachnoid casing. Thus, although these tumors are encapsulated, there is usually no obvious plane of separation between the tumor and perineurium. As a result, the seventh nerve has been sacrificed routinely. Two patients with posterior fossa facial neuromas underwent total tumor removal with a new surgical technique permitting preservation of the nerve fascicles via a translabyrinthine approach. Each patient has good recovery of seventh nerve function with no evidence of recurrence six and nine years later, respectively. Leaving the nerve fascicles intact appears to result in good reinnervation following total tumor removal. The potential value of this technique is best considered in the context of diagnostic and therapeutic options for facial neuromas in general. Neurotologists should find this a useful addition to their surgical armamentarium for selected cases.

Adult↗