Recurrent syncope as the presenting symptom of Arnold-Chiari malformation.
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Arnold-Chiari Malformation↗
Biomedical subjects
R T Zellem
Publications and source records attributed to R T Zellem.
Experimental peripheral nerve repair: environmental control directed at the cellular level.
This study recognizes recent advances in the understanding of the anatomy and physiology of peripheral nerves at the cellular level. It has reproduced study conditions originally advocated by de Medinaceli and coworkers, with modifications. Eighty-four rats were divided into three groups. Group A underwent sciatic nerve transection and standard perineurial repair. Group B nerves were frozen, severed with a vibrating blade, and reconnected by tubulization with a rubber cuff while bathed in solutions designed to inhibit Ca++-calmodulin activation, maintain colloid osmotic pressure, and mimic ambient electrolytic conditions. Group C underwent a similar procedure as group B, with the rubber cuff replaced by a polyglycolic acid mesh. All animals were randomized and evaluated functionally in terms of a sciatic index. By post-operative day 225, animals of group A recovered 37% of function, group B recovered 74%, and group C recovered 67%. Compound action potential recordings revealed a velocity recovery of 41% in group A, 70% in group B, and 81% in group C. Microscopic evaluation provided evidence for corresponding structural improvement. This new method of nerve repair is uncomplicated, relatively inexpensive, and easily adaptable to other animal models.
Animals↗
Multiple intracranial arteriovenous malformations: case report.
The authors describe a case of multiple supratentorial intracranial arteriovenous malformations in a patient with a family history of cerebrovascular disease. There was no sign of any other vascular dysplasia. A brief review of this rare entity is given.
Adult↗
Wounded by bayonet, ball, and bacteria: medicine and neurosurgery in the American Civil War.
The American Civil War was a holocaust that illustrated the mid-19th century's unpreparedness for the delivery of medical care to the mass casualties due to both wounds and disease. Several major considerations are offered to explain the soldiers' morbidity. Incomplete understanding of pathophysiology and its management is exemplified by the treatment of the battlefield head injury. Accepting these concepts and the extent of the knowledge of the time, that higher mortality did not occur is in part testimony to the admirable care that was rendered and human resilience in an effort to survive.
Brain Injuries↗