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R Tarrab

Publications and source records attributed to R Tarrab.

15 recordsLinked to original sources
PubMed1975

[Immunoelectrophoresis and double immunodiffusion in the diagnosis of human cerebral cysticercosis].

This paper describes the immune reactivity of the sera of humans with different probabilities of suffering cerebral cysticercosis as measured in immunoelectrophoresis and double diffusion against antigenic fractions from the wall, the liquid and the scolex of Cysticercus cellulosae. The proportion of positive sera with any antigenic fraction increased with the likelyhood of suffering cerebral cysticercosis, although some variation was found between antigenic fractions. Scolex and wall antigens showed the maximal discriminatory power between sick and healthy individuals: the probability of a false positive being less than 0.05 and that of a false negative ranging between 0.4 and 0.5. With these estimates it is concluded that a positive serum in immunoelectrophoresis or double diffusion against scolex or wall antigens practically establishes the diagnosis of cerebral cysticerocosis, although this event will occur in only half of the patients afflicted by the disease. The ease of execution of these tests and their discriminatory power between healthy and sick humans justify their establishment among diagnostic tools in cerebral cysticercosis.

Antigen-Antibody Reactions↗
PubMed1971

Stimulation in vitro with protein carrier of antibodies against a hapten.

Rabbits were immunized both with lysozyme and with dinitrophenylated bovine serum albumin. No antibodies against the dinitrophenyl hapten were produced when cell suspensions of their spleens were exposed in vitro to dinitro-phenyl-ovalbumin, whereas a positive response was obtained with dinitrophenyl-lysozyme. Moreover, when spleen cells from rabbits previously immunized with dinitrophenyl-bovine serum albumin were exposed in vitro to bovine serum albumin alone, they produced antibodies against the dinitrophenyl hapten.

Aminocaproates↗
PubMed1968

Studies on the advent of ureotelism. Factors that render the hepatic arginase of the Mexican axolotl able to hydrolyse endogenous arginine.

1. A study was undertaken of the conditions that might operate in the synthesis and hydrolysis of arginine by axolotl liver homogenate to test a previous postulate that liver arginase of the non-metamorphosed Mexican axolotl is not able to hydrolyse arginine formed from citrulline and aspartic acid, though it can split exogenous arginine, and also that an enhanced capacity to hydrolyse endogenous arginine plays a major role in the advent of ureotelism observed during the metamorphosis of the axolotl. 2. It was found that the arginase from axolotl liver is very unstable under the conditions followed, contrary to what is observed in rat liver. 3. Axolotl arginase is able to hydrolyse endogenous arginine if preserved. 4. Mn(2+) protects the enzyme and renders it able to split endogenous arginine. 5. It is suggested that the metal ion produces a change of conformation of the enzyme that, being stable, is capable of hydrolysing the amino acid, or that the new conformation is appropriate for interaction with the sites of arginine synthesis.

Animals↗
PubMed1965

Characteristics of arginases from ureotelic and non-ureotelic animals.

1. Livers of ureotelic and uricotelic animals possess the capacity, to a varying extent, of hydrolysing l-arginine and other guanidino compounds. 2. Three different enzymes responsible for such activity have been separated and partially characterized. They are the ;ureotelic' arginase, the ;uricotelic' arginase (both of them specific for l-arginine) and the guanidinobutyrate ureohydrolase (able to hydrolyse beta-guanidinopropionate, gamma-guanidinobutyrate and d-arginine but not l-arginine or guanidinoacetate). 3. The implication of the advent of a ;ureotelic' arginase in the integration of the Krebs-Henseleit cycle is discussed.

Acetates↗