A plea for a comprehensive perinatal database.
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Biomedical subjects
Publications and source records attributed to R Teele.
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Renal growth and function were studied in a sixteen year old recipient of a renal transplant from a 16 month old cadaveric donor. Within one month, as measured by sequential inulin and creatinine clearances, glomerular filtration rate was 40 ml/min, which was more than 6 times the estimated pretransplant clearance. Ultrasound of the transplanted kidney revealed longitudinal growth from 7 cm at transplant to 11.5 cm by 8 weeks post-transplant. Radionuclide renal scintiphotography confirmed rapid functional and dimensional growth. There was no evidence of rejection, obstruction, or other complications during the time the allograft rapidly increased in size. Thus this case demonstrates a remarkable capacity of the human kidney to hypertrophy rapidly.
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While congenital malformed and malpositioned livers are rare, they are relatively common in patients with omphaloceles. A malpositioned, malformed liver causing pyloroduodenal deformity and apparent pyloric obstruction in an infant or child with an omphalocele has not been previously reported. Thee such cases are described in which symptoms of upper gastrointestinal obstruction developed shortly after primary closure of the omphaloceles. Recognition of this condition at the time of primary closure of an omphalocele may allow consideration of additional procedures to prevent postoperative pyloric obstruction.