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R Templin

Publications and source records attributed to R Templin.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Cell electrophoresis studies of peripheral blood lymphocytes in patients following kidney transplantation].

In 111 patients (control group, dialysis patients, kidney recipients) the behaviour of T lymphocytes was observed using an automatic measuring apparatus ( Parmoquant cytopherometer ) and the spontaneous rosette test. The Parmoquant method gives no information on the process of rejection, but it helps to identify risk situations due to bacteria of viruses. In cases of rejection after the second post-operative week, the results of the two methods are reversed.

Electrophoresis↗
PubMed1982

[Immunologic after-care after organ transplantation using the electrophoretic mobility test].

55 of 113 receivers of cadaver donor kidney transplants could be control-examined and analysed postoperatively immunologically with the electrophoresis mobility test (EM test). A high coincidence appears in the group with clinical rejection symptoms and a rejections hint in the EM test (28 of 29) and also in the group with the rejection clinically not conceivable and with a negative test result (20 of 26). The EM test appears suitable for an additional support of the diagnosis "acute rejection". More cases should confirm this assertion.

Cell Movement↗
PubMed1981

[The electrophoresis mobility test (EMT) in the immunologic after care of patients with kidney transplantations].

Of 80 recipients of kidney transplants 46 patients could after operation immunologically be controlled by means of the electrophoresis mobility test. Here a good correlation to the clinically observed or not established immune responses was shown. The method seems to be suitable for a postoperative immunological control, needs, however, a testing in a great number of patients.

Erythrocytes↗
PubMed1980

Diagnostic value of urinary fibrin degradation products.

The concentrations of fibrin degradation products (FDP) in the urine were determined by the passive hemagglutination test in 115 patients with biopsy-proven chronic proliferating glomerulonephritis (GN), 93 patients with urinary tract infection (UTI) and 23 patients who received kidney transplants. The active GN values (12.3 micrograms/ml) are significantly higher than those for latent GN (0.3 micrograms/ml). Those for acute UTI (9.2 micrograms/ml) are significantly higher than for chronic UTI (1.3 micrograms/ml). In contrast to the reports published by others, the numerous 'false-positive' and 'false-negative' values make diagnosis of the activity questionable. Prognostic value can be expected in GN with the nephrotic syndrome (NS): patients with steroid-sensitive NS excrete FDP and patients with steroid-resistant NS excrete larger quantities of FDP. We have confirmed that a rise in the urinary FDP level in transplantation is indicative of rejection. However, since 10 of 27 rejections were FDP-negative, the absence of FDP in the urine does not preclude rejection.

False Negative Reactions↗
PubMed1980

[Determination of alanine aminopeptidase and lactate dehydrogenase in the urine as a control over the patient's course after kidney transplantation].

In 42 patients the determination of alanine aminopeptidase and lactate dehydrogenase in the urine was performed after transplantation of a kidney. In the evaluation of the enzyme activities it was referred to the clinically made rejection diagnosis as well as to the increase of the serum creatinine. We found out that with regard to the clinically made rejection diagnosis the alanine aminopeptidase in 56% and the lactate dehydrogenase in 55% of the cases showed an increase before the beginning of the rejection therapy. Before the corresponding increase of the serum creatinine we could establish an increase of the enzyme activity in the alanine aminopeptidase in 45% and in the lactate dehydrogenase in 65% of the cases. For a better interpretation of the urinary enzyme activities during the rejection crises the average activities of the enzymes immediately after the dismissal of the patients as well as three months, six months and one year after the transplantation are cited. From our investigation results that the daily determination of alanine aminopeptidase and lactate dehydrogenase in the urine is suited, taking into consideration other possible influence factors on the enzyme activity as well as other parameters, to support the diagnostics in finding the rejection after the transplantation of a kidney.

Aminopeptidases↗
PubMed1980

[Therapeutic procedure in acute ulcer hemorrhage after cadaver donor kidney transplants].

In 62 cadaver-donor-allograft recipients we observed 11 times gastrointestinal complications 7 times (11%) an ulcer or an erosion of the mucous membrane could be secured gastroscopically. The therapeutic remedy of choice seems to be the well-timed 2/3-resection after Billroth II, since a too long hesitation increases the number of complications, has a negative influence on the choice of the intervention and increases the lethality.

Acute Disease↗
PubMed1979

[Critical considerations on the production of a pulsating fluid stream].

Two types of gears are used for perfusion of cadaveric kidneys. Electric models are presented for both types and the optimal devices are discussed. Based upon in vivo conditions, the relevant parameters are transferred to the model and an according equipment for pulsatile fall-stream perfusion is presented, which is compared with another gear. The clinical criterion for good initial perfusion is the erythrocyte count in the initial perfusate. Judged from that, the chosen device is significantly better than its predecessor.

Biophysical Phenomena↗
PubMed1979

[Organ preservation in intra- and extracorporeal kidney surgery].

With the help of cases of own patients is reported on the possibility of organ preservation in intra- and extracorporal renal surgery. In 5 patients with tumours, 3 patients with coral calculi and one patient with an extended disease of the ureter five times the extracorporal renal surgery with following autotransplantation and initial pulsatile fall stream perfusion was performed. Four times the in-situ-perfusion with hypothermic Collins solution and in-situ-operation was performed. Indication and advantages for the different methods are demarcated.

Adenocarcinoma↗
PubMed1978

[Possibilities and limits of kidney transplantation].

Chronic haemodialysis and renal transplantation are mutually supplementing methods for the treatment of patients with terminal renal lesion. The two methods have proved their worth in clinical practice. The expectance of life of patients with chronic renal insufficiency could essentially be improved during the last years. In last consequence the successes of the transplantation of kidneys depend on the solution of immunobiological problems, which are not yet cleared up nowadays. 1. In the determination of genotypical determinants possibly not all are known or recognizable. 2. The at present clinically usable examination methods do not yet allow to recognize rejections so early that by an aimed immunosuppressive treatment irreversible damages on the graft may be prevented. After a transplantation of kidneys of relatives a long survival time of transplanted patients is better than after a transplantation of kidneys taken from dead bodies. The rejection is still the main factor of the failure of the graft, the sepsis is the most frequent cause of death. It is neccessary, to develop less toxical remedies for the adaptation of the graft. Nevertheless, thousands of optimally transplanted patients prove the usefulness of the allogenic transplantation of the kidney.

Female↗
PubMed1978

[Enzymatic and morphologic studies on long-term perfused dog kidneys].

21 canine and 12 human kidneys were submitted to long-term perfusion for 24 hours. During that time LDH-activity, histologic, enzyme-histochemic, and ultrastructural examinations were carried out. The findings proved that kidneys with lesser damage from ischemia showed lower activities during the first 4 to 6 hours than kidneys which were more injured before. The latter showed the same ultrastructural alterations as kidneys after perfusion for 24 hours, which suggests an irreversible partial damage of the organ.

Albumins↗