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Biomedical subjects

R Thieme

Publications and source records attributed to R Thieme.

13 recordsLinked to original sources
PubMed1979

[Visual field response to hypotension following oculopression (author's transl)].

The authors studied the visual fields in 100 healthy persons of different ages before and 10 min after oculopression. They found a depression of the I/2 isopter mostly in the nasal lower quarter of the visual field in persons over 60 years old, due to a disturbed or diminished vascular compensation of bulbus compression. They consider that oculopression might have clinical importance as an indirect provocation test of the cellular blood circulatory system.

Adolescent↗
PubMed1979

[Application of computer tomography (CT) as an additional means of follow-up gynecologic neoplasms-a case documentation (author's transl)].

The application of CT represents an important progress not only in diagnostic and therapeutic planning, but also in the evaluation of the effectiveness of follow-up procedures in gynecologic cancer therapy. The evaluation of the results of some follow-up procedures in a case of leiomyosarcoma uteri shows significance and importance of CT as a new radiologic method. Inspite of preliminary negative results of extensive radiologic, myelographic, laboratory investigations and of technetium- and gallium-scintigraphy, CT proved a solitary metastasis located at S-1 in the os sacrum. The diagnostic aspects of follow-up examinations in patients undergoing cytoreductive surgery or radiotherapy are discussed. CT should not be placed at first rank position, but be considered as an helpful additional means for special cases.

Bone Neoplasms↗
PubMed1979

[The effect of preventive cesarean section in breech presentation on perinatal mortality].

This study is based upon 1229 infants delivered from breech presentations who were investigated for the influence of the prophylactic Caesarean section carried out with primiparae after their 36th week of pregnancy in 1972, on perinatal mortality. The periods under report, i. e., 1966 to 1971 and 1972 to 1975, were compared with one another. The incidence of Caesarean sections carried out in breech presentations increased from 11.6% to 52.2%. With a premature birth rate of 22.1% and 20.9%, respectively, the uncleaned perinatal mortality decreased from 109.2% to 96.5%, whereas the cleaned one dropped from 73.3% to 64.2%. As to mature infants delivered vaginally or by Caesarean section, there was no significant difference in death rates. The worse prognosis for breech presentation infants given birth by pluriparae could be confirmed. The high portion of underweight infants amounting to 78.0% and 82.9%, respectively, in the total number of perinatal deaths illustrates the main problem of the breech presentation births.

Birth Weight↗
PubMed1978

The effect of the mode of administration of nitrogen mustard and cytosine arabinoside on the production of chromosomal aberrations in mouse bone marrow and ascites tumour cells.

The cytogenetic effects of intraperitoneally (i.p.) and subcutaneously (s.c.) administered nitrogen mustard (HN2) and cytosine arabinoside (ara-C) on bone-marrow and ascites tumour cells of mice were studied. Ehrlich ascites tumour-bearing mice were treated with the mutagens, and cytological preparations were made from ascites tumour and bone-marrow cells of the same animal. The following parameters were investigated: frequencies of mitotic and chromosomal aberrations, time of aberration maxima and aberration spectra. HN2 (0.68 mg/kg b.w.), when given i.p., induced in ascites tumour cells a strong inhibition of mitotic frequency and very high aberration rates, whereas in bone marrow no aberrant chromosomes were observed. On the other hand, after s.c. administration, the same dose induced more aberrant metaphases in bone marrow than in tumour cells. Ara-C (315 mg/kg b.w.) resulted, after s.c. administration, in higher aberration frequencies both in ascites and bone-marrow cells compared with i.p. treatment. All ascites tumour cells showed higher aberration requencies than bone-marrow cells. In bone marrow the aberration maximum occurred as soon as 6 h after treatment. Furthermore, clear differences with respect ot the types of aberration found in the two systems were evident. The differences caused by the different modes of administration in two different types of cell are discussed in terms of metabolic inactivation and differences of the two tissues with respect to karyotype, cell cycle time and repair capacity.

Animals↗
PubMed1977

[Effect of early feeding with glucose solution on the incidence of hypoglycemia in dysmature and hypotrophic newborn infants].

Dysmature and small-for-date infants we fed with solution glucosi 20% in a first group of the 12th hour of life, in a second group of the 6th hour. The blood-glucose value in the first three days of life we found in the second group significant greater than in the first group. The hypoglycemia-rate in the first group was 9,2% in the second group 0,6%.

Blood Glucose↗
PubMed1977

[Trace-element concentration in the human placenta in a strong contaminated environment (author's transl)].

By means of NAA the content of trace elements in human placentae from a strong contaminated environment (Essen) was determinated and compared with former results from Bavaria. The data show highly significant elevation of the concentration of Cd, Cr, La and Br in Essen, which counts for the industrial waste of this region. In contrast the element As is highly increased in placentae from the rural Bavarian districts. This may be caused by the wide spread application of plant protective insecticides in the past.

Arsenic↗
PubMed1975

[Trace elements in the human placenta (author's transl)].

The determination of the mentioned elements was carried out by the neutron activation analysis with lollowing radio-chemical separation. The comparison of trace elements in the human placenta from different regions of Bavaria showed a high concentration of Sb, Br, La and Co in Munich. This fact is explained by the environmental pollution of the large city. Placentas from the Bavarian forest contained a higher amount of Ce and Hg. Cer is contained in the rock of this region. The increase in Hg from that region is unexplained.

Antimony↗