Biomedical subjects

R Tye

Publications and source records attributed to R Tye.

11 recordsLinked to original sources

PubMed1996

Updating small area population estimates in England and Wales.

"Population estimates have important implications for resource allocation within government and commerce, and are often assumed to be without error. Currently, central government provides annual population estimates for all the local and health authority districts in Britain, but estimates are needed for smaller areas, typically for electoral wards and postal sectors. Small area estimates are provided by some local authorities and commercial organizations, using different methods; the accuracy of these estimates is modelled here within a multilevel framework. Certain characteristics of the small area and of the method of estimation are included as explanatory variables. Results show that the method of estimation used is of great importance."

Developed Countries↗

PubMed1995

Constructing an urban deprivation index: a way of meeting the need for flexibility.

The authors examine the use of census data to construct an urban deprivation index for the United Kingdom, with special attention given to the need for flexibility. "A single index is rejected in favour of a matrix of results which captures the complex geography of deprivation. The matrix of districts includes measures of the degree of deprivation, its spatial extent, its intensity, and the spatial distribution of deprivation at the enumeration district scale. The profiles of various districts are discussed to illustrate the use of the matrix."

Censuses↗

PubMed1980

The preparation of lipid-free extracts of drugs from blood for gas chromatographic analysis.

A method is presented to separate co-extracted biological materials, in particular lipids, from drugs in chloroform extracts of blood. The chloroform is evaporated and the residue is dissolved in a small volume of petroleum ether and partitioned with eight times this volume of 5% aqueous hydrochloric acid. The acidic, basic, and neutral drugs are extracted into the aqueous phase, leaving unwanted materials in the petroleum ether. The recoveries of drugs representative of a variety of types are presented. Reduction of the levels of lipids by factors on the order of 1000-fold is reported.

Centrifugation↗

PubMed1977

Fungal growth on C1 compounds: quantitative aspects of growth of a methanol-utilizing strain of Trichoderma lignorum in batch culture.

A study was made of some salient parameters that influence growth of the methanol-utilizing fungus Trichoderma lignorum growing in batch culture on a minimal medium containing methanol as the sole source of carbon. Maximum cell yield was recorded at the expense of 1.58 g of methanol per liter. Inhibition was observed with methanol concentrations in excess of 4.7 g/liter. The optimum temperature for fungal growth was 23 degrees C. Growth of the fungus was directly proportional to an inorganic nitrogen concentration up to 0.2 g of NH4NO3 per liter. No inhibition of growth occurred at any concentration of NH4NO3 up to 11 g/liter. The pH of the growth medium decreased from 7.0 to 3.5 during growth of the fungus on methanol, which may have been due, in part, to the accumulation of trace amounts of organic acids in the growth medium. An analysis of the commercial potential of the fungus, as a source of edible protein, indicated that the strain of methanol-utilizing T. lignorum used was uneconomical in terms of the yield and the specific growth rate.

Dietary Proteins↗

PubMed1974