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Biomedical subjects

R Unsöld

Publications and source records attributed to R Unsöld.

8 recordsLinked to original sources
PubMed1992

[Postmortem endoscopic diagnosis].

The use of endoscopical methods augments the macroscopical diagnosis in autopsies. Cavities and sinuses which are hardly accessible may be inspected and photographically documented as well without damage of the anatomical context. In terms of forensic autopsies the endoscopical technique is mostly recommended for the inspection of the fundus of the eye, the external auditory meatus up to the tympanic membrane, the naso- and laryngopharynx. Pathological and traumatical changes can be valued at once in situ. Forensic evidence of postmortal endoscopical findings is exemplified.

Adolescent↗
PubMed1989

[Initial manifestation of sarcoidosis as a palpebral and para-bulbar tumor].

Tumors of the lids, the lacrimal gland and the orbit can be early manifestations of sarcoidosis. A timely diagnosis based on biopsy of periocular tissues and cinico-radiographic evaluation at an early stage of the disease may prevent irreversible lesions of the parenchymatous organs. The clinical and histological signs in two patients, one with palpebral and one with parabulbar sarcoidosis, are described and the differential diagnosis and therapeutic aspects are discussed.

Aged↗
PubMed1979

[Ct-criteria of orbital hemangiomas and their importance in differential diagnosis of intraconal tumors (author's transl)].

CT-scans of 29 histologically proven cavernous hemangiomas were evaluated with respect to their location, shape, delineation from surrounding tissue, contrast-enhancement, and secondary changes of the bony orbit. Whenever a round or oval tumor, located in the outer upper muscle cone, sharply delineated from surrounding tissue, unattached to optic nerve and ocular muscles, spares a small triangular space in the orbital apex, it is in all probability a cavernous hemangioma. Evaluation of the tumors shape and its separation from surrounding tissues requires imaging in multiple sections in two planes oriented, if possible, at right angles. -- Changes in position of the optic nerve and eye muscles in different directions of gaze demonstrated by CT rule out significant tumor-attachments. The portion of the intraconal space least affected by optic nerve shifts and muscle contractions during eye movements, as demonstrated by CT, is the upper outer quadrant, the site preferred by the mobile tumor. -- Tumors which cannot be differentiated from cavernous hemangiomas by CT-criteria are rare usually benign. Reports of rare examples of well delineated or encapsulated malignant intraconal lesions indicate the possibility -- however remote -- of mistaking a malignant tumor for a cavernous hemangioma by CT.

Diagnosis, Differential↗
PubMed1979

[Gaze induced monocular obscurations with cavernouse hemangioma of the orbit. Computer-tomographic demonstration of orbital anatomy in various positions of gaze (author's transl)].

A young woman with only minimal proptosis from a cavernous hemangioma of the left orbit complained of monocular obscurations of vision evoked by right alteral gaze. By analysis of the symptoms, we excluded direct compression of the globe, the optic nerve, and the ophthalmic artery as well as a retinal electrophysiologic phenomenon as a cause of the obscuration. Some vascular phenomenon occurring within the muscle cone appeared to be the most likely explanation. Computer tomography in various positions of gaze revealed the dynamic anatomical relationship between optic nerve and tumor. During adduction, the nerve pressed against and shifted beneath the tumor in the region where the ophthalmic artery crosses over it.

Adult↗
PubMed1978

[On the differential diagnosis of inflammatory illness of the orbit. Computer tomographic results (author's transl)].

Selectet CT-findings in inflammatory orbital diseases are demonstrated with special regard to the differential diagnostic importance of details. Based on the criteria-density of retrobulbar fat, swelling of extraocular muscles, dilatation of orbital vessels, representation of osseous borders of the orbit, pneumatisation of paranasal sinuses etc-typical CT-patterns of disease entities are demonstrated. The differentiation of inflammatory diseases, orbital tumors, and vascular disorders is discussed. The limits of diagnostic interpretation are pointed out.

Aged↗
PubMed1976

The laser in the Lowry technique for microdissection of freeze-dried tissue slices.

A new technique for tissue microdissection is described. This procedure, using an u.v.-laser micropreparation instrument, overcomes the extremely time-consuming manual preparation. The u.v.-laser micropreparation design allows fast, precise, reproducible and smear-contamination-free tissue microdissection. The preparation of the tissue sample can be programmed by tracing out the area to be sampled with a non-destructive 0.5 mW He-Ne-laser aiming-beam. The tract is stored in a small electronic unit, which then guides the motor-driven stepping stage on the microscope in the actual dissection run with the u.v.-laser. The laser power is adjustable in the range 4 to 40 kW and controlled by a photo diode displayed on an oscilloscope screen. In the tissue slice, prepared according to Lowry, an unlimited number of cells or tissue compartments can be dissected and afterwards weighed. The procedure described offers a broader use of the quantitative microhistochemical techniques of Lowry and of Neuhoff.

Acid Phosphatase↗