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Biomedical subjects

R Vasile

Publications and source records attributed to R Vasile.

10 recordsLinked to original sources

[Open versus laparoscopic treatment in inguinal hernia. Our experience].

The knowledge acquired in recent years in the field of etiopathogenesis of materials for prosthesis and of surgical technics regarding inguinal hernias together with a renewed interest for local-regional anesthesia has created a real revolution in a field that for almost 100 years had been dominated by the same uncontrasted ideas. The fundamental stages in the evolution of surgical technics are reviewed as well as the most recent discoveries in the field of biochemical textiles and prosthesis available today that have contributed to the development of new surgical methods. These, distinguishing between "open" and laparoscopic technics, are compared on the basis of the data found in the literature concerning recurrence, morbidity, period of convalescence and costs. Personal experience concerns the last four years with 632 patients treated, some in emergency conditions and others in programmed operations, using the foremost methods of "open" surgery but preferring, among these, those that are tension free. The follow-up involved 84% of the patients for a period of no less than 18 months. A reduction of complications and of relapses was obtained: 5-9% in traditional operations against 0.5% for those that were tension free. With this type of operation the postoperative hospitalization was considerably reduced so that 35% of them could fit into the "one day surgery" category. On the basis of these results it is stressed that both the laparoscopic technics and the tension free technics offer advantages as compared to so called traditional methods; however, even though the first type seems to assure a shorter postoperative period, there is the inconvenience of higher costs and the necessity of general anesthesia.

Follow-Up Studies↗

A prospective follow-along study of the course of social phobia.

The goals of this study were to delineate the courses of social phobia and to determine whether the course of generalized and specific social phobia differed. In the Harvard/Brown Longitudinal Study of Anxiety Research Project, 66 specific and 74 generalized social phobic subjects were identified for whom adequate course data were available. These subjects had been followed prospectively with a standardized follow-along measure of psychopathology. The probability of remission was calculated for each individual group and both groups combined. Demographics were the same for both groups except that the specific social phobia group had a marginally higher mean score on the Global Assessment Scale. Complete remission for the combined group was not different from that for either subgroup and was 0.11 at 65 weeks. Social phobia appears to be a disorder with considerable long-term morbidity. Surprisingly, both subtypes took a comparably long time to remit and were similar in their high level of psychosocial dysfunction.

Adult↗

A prospective, follow-along study of the course of social phobia: II. Testing for basic predictors of course.

This study examined the 65-week outcome of a group of subjects with social phobia to determine predictors of course. Social phobic patients in the Harvard/Brown Anxiety Disorders Research Project study were followed for 65 weeks using the Longitudinal Interval Follow-Up Evaluation-UpJohn scale. The following variables did not predict outcome over the course of the study: sex, age of onset, duration of illness, lifetime history of various anxiety disorders, current comorbidity of anxiety or depressive disorders, Global Assessment Scale score, or measures of role functioning. We find that in a social phobic population with a mean duration of illness of 18 years, none of the tested variables examined predicted 65-week outcome.

Age of Onset↗

Comparison of personality disorders in different anxiety disorder diagnoses: panic, agoraphobia, generalized anxiety, and social phobia.

Recently there has been increasing interest in the relationship of the personality and the anxiety disorders. This paper presents comorbidity findings between DSM-III-R personality pathology and several DSM-III-R anxiety disorders and makes direct comparisons between anxiety groups. This is the most extensive comparison of this kind reported thus far. This report is on the first 475 anxiety patients who were recruited from multiple sites to take part in a naturalistic study of anxiety. All had a DSM-III-R diagnosis of panic, agoraphobia, social phobia, or generalized anxiety disorder (GAD). Previous studies which found a high comorbidity between the anxiety and the personality pathology were confirmed, with a significantly higher prevalence of personality pathology occurring with social phobia and GAD. Among our patients, all of whom had anxiety disorders, the presence of comorbid major depression is associated with an increase in the levels of comorbid personality pathology--as previously described in the literature. The relationship between low social functioning and the presence of personality pathology was confirmed, however, the relationship appears to be specific to certain areas of functioning, a new finding. There is a clinically important relationship between Personality Diagnostic Questionnaire--Revised personality pathology and the anxiety disorders characterized by different prevalences of personality disorders in different anxiety disorders and specific areas of social dysfunction.

Adult↗

[Not Available].

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Demography↗

[Primary carcinoma of the gastric stump. Physiopathological, diagnostic and therapeutic considerations].

Even though the primary carcinoma of the gastric stump is a tumor that will diminish in frequency in the years to come, it is still a topic of scientific studies. The authors report their experience with four cases of primary carcinoma of the gastric stump treated surgically as compared to 89 cases of carcinoma of the stomach operated in the same period. After some comments on the etiopathogenesis that is at the basis of the neoplastic mutations of the remaining gastric epithelium, clinical, prognostic and pathologic features that differentiate this type of tumor from those which develop in unoperated stomachs are examined and, then, the most frequent therapeutic approaches are illustrated. In conclusion, it is sustained that patients who have undergone partial gastrectomy for benign disease should be closely followed-up from the tenth year after the operation and, in any case, in those who are over fifty years of age.

Adult↗

[Torsion of the greater omentum as a rare cause of acute abdomen].

Taking as their starting point a case of greater omental torsion recently observed in their surgical department, the authors carefully review the topic and the relevant literature data. This is a rare condition, which though presenting diagnostic difficulties which make it hard to identify preoperatively, poses no problems of a therapeutic nature.

Abdomen, Acute↗

[Carcinoma of the pancreatic body and tail].

Carcinoma of the body and tail of the pancreas still remains the disease form with the worst prognosis and evolution. In spite of a huge improvement in diagnostic methods, anaesthetic and surgical procedures and pre- and postoperative assistance, the results in terms of early diagnosis and long-term survival have been generally disappointing. The authors describe their own experience regarding three such tumours treated in five years, analysing the literature data, and referring to the current guidelines in diagnostics and surgical therapy. They then go on to propose a step-by-step approach to the management of these patients. The difficulty of obtaining an early diagnosis of the disease which derives from many factors, such as unspecific and late appearing symptoms, is stressed. They conclude by confirming the need to perform a radical resection, if possible, which, together with a combination of radio- and chemotherapy, is the only procedure capable of holding out some hope of a cure.

Adenocarcinoma↗

[Liver transplantation--considerations over 8 cases operated in the year 2000].

In the year 2000, at the Department for General Surgery and Liver Transplantation from The Fundeni Clinical Institute Bucharest, seven OLTs and one living-related transplantation were performed in 6 adults and 2 children. Postoperative complications were: bile leakage, hemoperitoneum, lower gastrointestinal hemorrhage, parietoabdominal hematoma. There was only one postoperative death due to septic complications in the 18th p.o.d. and one late death due to pneumonia of unknown origin. After the results in the year 2000 there was an increased number of donors and referrals. We consider that now in Romania this is an established program that will continue depending on the number of donors and financing.

Adult↗