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Biomedical subjects

R Vasiu

Publications and source records attributed to R Vasiu.

14 recordsLinked to original sources

Automated estimation of nuclear volume in brain tumors.

The comparative study of the percentage nuclear area in brain tumors by the point-counting technique and digital analysis showed a good correlation between the results obtained. The investigation suggests the possibility of using the volume corrected mitotic index to tumors with uniformly distributed cells.

Astrocytoma

Composite endocrine cell, typical adenocarcinoma and signet ring carcinoma of the gallbladder.

The authors report a case of composite tumor of the gallbladder which exhibited features of both adenocarcinoma (with typical areas, signet ring cells and clear cells) and endocrine cell carcinoma. The histological picture suggests the origin of both components in a common primitive cell with the capacity to differentiate to different types of metaplastic epithelium and supports the hypothesis of a sequence metaplasia--dysplasia--carcinoma.

Adenocarcinoma

Gastric Burkitt's lymphoma. Case report and review of the literature.

A case of gastric Burkitt's lymphoma with pancreatic infiltration in a 15-year-old boy is reported. Local lymph nodes were not involved. Review of the literature disclosed that the reported cases of Burkitt's lymphoma were localized in the intestine. The origin, evolution and prognosis of gastrointestinal lymphoma are briefly discussed.

Adolescent

DNA nuclear content of apocrine cells in fibrocystic mastopathy and breast cancer.

The DNA nuclear content of apocrine cells was studied in 5 cases of fibrocystic disease, 3 cases of invasive duct carcinoma and 3 cases of invasive lobular carcinoma. Both diploid and aneuploid values were found in each group. The possible significance of apocrine change in breast lesions is discussed.

Apocrine Glands

Morphometric grading of laryngeal squamous cell carcinomas.

The authors have used the point counting method for the morphometric assessment of the histological aspect of laryngeal carcinoma. The results suggest that subjective histopathological grading tends to overestimate the tumor grade. The implications of these data for the prediction of prognosis and selection of therapy are briefly discussed.

Carcinoma, Squamous Cell

Cytophotometric study of DNA content of cells in type III cervical smears.

Cytophotometric study of suspicious (group III of the Papanicolaou's classification) smears shows the heterogeneity of this group, which includes cases with diploid--tetraploid DNA modes, cases with a wide distribution of DNA values and aneuploid cases. The significance of these findings in relation with the biological properties of cells is briefly discussed.

Cervix Uteri

Relationship between structural and ionic changes in cardiosclerosis.

The parallelism between hypoxic changes in the myocardium revealed by Lie's technique and by fluorescence microscopy and the ionic changes (Na+, K+, Ca2+) was studied in 51 autopsy cases. The Lie technique was positive in 52.6 per cent of the cases of cardiosclerosis with myocardial infarction and in 15 per cent of the cases of cardiosclerosis without infarction, while fluorescent areas were found in all cases of infarction and in 35 per cent of cardiosclerosis cases without infarction. Na+ and K+ were decreased and Ca2+ ions were increased in both ventricles and in both sexes, both in infarctions and in cardiosclerosis cases without infarction. Ionic changes are more probably related to the intensity of cardiosclerosis rather than to age or sex.

Adult