Utero-placental circulation was studied using a gamma-camera which measures the appearance of a radio-active bolus of transferin tagged with Indium 113 in the region of the placenta and of the myometrium. The technique adopted for the calculations that are carried out allows a ratio between the placental blood flow and the myometrial blood flow to be established. The measurements that were taken in the last trimester of pregnancy showed that there was a significant difference between the ratio in normal pregnancies and in those that resulted in the deliveries of small-for-date babies. The foetus is small-for-date in 80 per cent of cases when the placental blood flow (Dp) to the myometrial blood flow (Dm), ratio is less than 80. It is small-for-dates in 25 per cent of cases if the Dp/Dm is between 0.80 and 1.60. If the Dp/Dm ratio is about 1.60 the foetus is normal in 93 per cent of cases. When we compared especially the variations between the Dp/Dm ratio during the administration of Salbutamol, we showed in the light of work already published that the intravenous administration of 50 mug of Salbutamol brought about a lowering of resistance in the placental blood vessels, and probably an increase in the blood flow at the maternal placental site, whereas, on the other hand when 500 mug of Salbutamol were injected intravenously the result was a deficiency in placental blood flow.

Albuterol↗

PubMedDate not supplied

[Evaluation of cardiac involvement in advanced rheumatoid arthritis. Clinical, electrocardiographic, echographic and gallium and thallium double scintigraphic study of 28 patients].

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Adult↗

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[Computerized tomography of the distribution of N-isopropyl-p-123 iodoamphetamine in cerebrovascular pathology. Comparison with studies using the 133-xenon inhalation method].

123Iodo-Amphetamine (IAMP) brain distribution was studied with a specially dedicated multilevel tomographic system in 30 patients with vascular ischemic (18) or hemorrhagic (12) disorders. Results were compared with clinical data, CT scan and rCBF measurement obtained by the 133Xe continuous inhalation method. Abnormalities with IAMP were found in 27 cases, in good agreement with the results obtained by the Xenon inhalation technique in 21 studies from the 22 where that method was possible. For 80% cases there was also a good agreement between the results obtained by the IAMP and CT scan: one case normal, and 23 observations with abnormalities. This is true for the localization of lesions, but IAMP appears able to shown remote abnormalities, i.e. crossed cerebellar diaschisis or functional deactivation, in the absence of CT scan lesions in the corresponding areas. This is of particular interest in the protracted regressive ischemic neurologic disorders (PRIND): CT scan were normal in all five observations but IAMP showed abnormalities in four cases. IAMP is however very expensive, so it has to be used only when 133Xe inhalation is technically impossible.

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