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Biomedical subjects

R Verschraegen

Publications and source records attributed to R Verschraegen.

17 recordsLinked to original sources
PubMed1979

Double blind study of meptazinol versus pentazocine and placebo in postoperative pain treatment.

The purpose of this double blind study was to evaluate the efficiency and safety of a new analgesic drug meptazinol, compared to pentazocine and placebo, in patients suffering from postoperative pain. Subjective and objective parameters were controlled. It appeared clearly that meptazinol had a potent analgesic effect with rapid onset, but rather short duration. Analgesic effect of pentazocine appeared more slowly, but persisted for a longer time. The two active drugs had no effects on the objective parameters measured.

Azepines↗
PubMed1976

Meptazinol: I.M. use in postoperative pain.

In a population of 39 patients, the new analgesic drug Meptazinol was tested in postoperative period at a dose of 100 mg I.M., administered only on request of the patient. Cardiovascular and respiratory parameters were not altered significantly. The onset of analgesia was rapid (+/- fifteen minutes) with a maximum reached after thirty minutes; the provided analgesia was good for about two hours as evaluated by the anesthetist and the nurse. The patient asked for a new dose only after about five hours.

Analgesics↗
PubMed1976

Clinical use of meptazinol.

Meptazinol, a new analgesic, was used at two different times of surgery: a) by the I.V. route peroperatively (1.6 mg/kg bodyweight with a maximum of 125 mg), b) by the I.M. route postoperatively (100 mg). When used I.V. peroperatively it does not seem to be a real progress, due to its poor neurovegetative protection and side-effects. However used I.M. postoperatively it seems a good analgesic drug with rapid onset and with few side effects.

Adult↗