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Biomedical subjects

R Vimala

Publications and source records attributed to R Vimala.

8 recordsLinked to original sources

Oat cell carcinoma of the oesophagus--a case report and review of literature.

A 45-year-old male presented with dysphagia, anorexia and progressive weight loss. He was a chronic smoker. Oesophagoscopy showed an ulceroproliferative growth of 25-30 cm size. Histopathology from the biopsy tissue showed small cell (oat cell) carcinoma. He received radiotherapy, but died 9 months later. Small cell carcinoma of the oesophagus constitutes 0.8-2.4% of all the oesophageal carcinoma. The tumour is an aggressive one with a poor prognosis irrespective of the treatment.

Carcinoma, Small Cell↗

Antiinflammatory and antipyretic activity of Michelia champaca Linn., (white variety), Ixora brachiata Roxb. and Rhynchosia cana (Willd.) D.C. flower extract.

Methanolic extracts of the flowers of M. champaca, I. Brachiata and R. cana were found to possess antiinflammatory activity against cotton pellet granuloma in rats at a dose level of 100 mg/kg body weight, sc. The latter two drugs showed higher activity (AIA) as compared to that of M. champaca. They reduced the protein content, acid phosphatase, glutamate pyruvate transaminase and glutamate oxalo-acetate transaminase activities in liver and serum. A significant reduction in the ascorbic acid content in adrenals was also observed in drug-treated animals. R. cana was recorded to possess significant antipyretic activity from the first hour of administration. These pharmacological properties may be traced to the presence of flavonoids in the flowers of these plants.

Analgesics, Non-Narcotic↗

Gastric teratoma in an infant.

A 40-day-old male infant had massive gastric teratoma. Histologically, it had immature neural elements, among the glial masses. In most of the reported series, the tumor was benign. Malignancy in gastric teratoma is extremely rare.

Humans↗

Xanthelasma of esophagus and stomach.

Gastric xanthelasma, a benign condition, has been reported before; there has been no documentation of xanthelasma of the esophagus. We report a patient with xanthelasma of the stomach and esophagus.

Adult↗

Duodenal amyloidosis.

Amyloidosis of the gastrointestinal tract is often asymptomatic. We report a 65-year-old man who presented with anorexia, dyspepsia and vomiting. Endoscopy showed nodular duodenal mucosa, which on histology showed amyloidosis. The patient died two weeks later.

Aged↗