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Biomedical subjects

R Vitolo

Publications and source records attributed to R Vitolo.

4 recordsLinked to original sources

Easy Medic: an Internet application for the general practitioner.

A research project has been carried out to develop a client server application which supplies the general practitioner (GP) with a 'personal digital assistant' (hand-held mobile computer) to connect to Web servers at a hospital site through the Internet. This allows the doctor to book medical examinations, hospital admissions and manage patient data. The application used advanced object-oriented techniques, on both the client and the server side. The connection to a Web server was achieved through GSM wireless cellular telephones using standard Internet protocols (HTTP, TCP/IP and CGI). Conventional telephone lines can be used as well. Other application modules on the client side provided patients medical record supervision, GP schedule management, general information about hospitals and clinics, and pharmacy consultation. These services should help GPs in their daily work. Moreover, the quality of health-care resource management and cost supervision should improve, since each GP 'transaction' is automatically entered in realtime into a database at the server. The services are under test in the health-care system of an urban area in southern Italy.

Computer Communication Networks↗

Hepatitis in children with thalassemia major.

Since thalassemia major patients are transfusion dependent, they are at a particularly high risk of contracting post-transfusion hepatitis. In this study, 36 transfusion-dependent children were followed up for evidence of viral hepatitis. Of 23 with increased ALT levels, 17 were anti-CMV and 12 were anti-HCV positive, 9 were positive for both CMV and HCV. Of 13 children with normal transaminase levels, 5 were CMV positive and 3 were HCV positive. These results show that CMV may be a very common cause of non-A, non-B hepatitis in transfusion dependent thalassemic children.

Adolescent↗

Hepatitis in pre-school children: prevalent role of cytomegalovirus.

Virological and serological investigations were performed on 8 children with clinical and/or laboratory signs of hepatitis. Cytomegalovirus (CMV) appeared as the most frequently involved etiologic agent, since it was associated with 5 severe or chronically-evolving cases. Out of the other 3 patients with non-CMV associated hepatitis, all completely recovering, two had clinically typical Epstein-Barr virus infections, while the remaining patient had an asymptomatic HBV infection.

Acute Disease↗

[Trisomy 18 with unusual clinical and chromosome features].

The Authors describe a newborn with costal hypoplasia and vertebral malformation, tracheoesophageal fistula, congenital heart disease and closed hands with the second and third finger overlapping. Cytogenetic findings indicated trisomy 18 [47, XX, -1, +der(1), +der(18), t(1;18) (q1.2; p11.3)] inherited by mother's carried balanced translocation 1q/18.

Abnormalities, Multiple↗