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R W AINSWORTH

Publications and source records attributed to R W AINSWORTH.

6 recordsLinked to original sources
PubMed1963

FOUR CASES OF WALDENSTROEM'S MACROGLOBULINAEMIA.

The clinical course and pathological features of four cases of Waldenström's macroglobulinaemia are described. One was associated with a localized carcinoma of the bronchus and one with a chromophobe adenoma of the pituitary. Trypsin digest preparations of the retina were examined in two cases, one with severe retinopathy and the other with no clinical evidence of ocular disease, and the findings are briefly described. The aetiology of the anaemia is discussed. Haemolysis due to circulating autoantibodies was not demonstrated in any of the cases. Erythrophagocytosis was a prominent feature in case 4, of moderate degree in cases 1 and 2, and inconspicuous in case 3. It was not proportionate to the serum macroglobulin levels. The cytological and histological features in all four cases are distinctive, and their value in differential diagnosis is stressed.

Geriatrics↗
PubMed1961

Pathological changes in temporal arteries removed from unselected cadavers.

Progressive degenerative changes in ageing temporal arteries are described. These changes are usually severe in elderly patients, hence their presence in diagnostic biopsies provides no evidence of temporal arteritis past or present. In two patients in the series of random necropsies examined there were changes in the temporal arteries identical with those seen in patients known to have suffered from temporal arteritis in the past; in both these cases there was, in addition a giant cell aortitis. The distinction between healed arteritis and degenerative changes due to age in a single biopsy specimen may be difficult. Furthermore, it is possible that steroid treatment may arrest the progress of the disease so that gross intimal thickening and vascularization of the artery wall do not occur. Giant cell arteritis is not a rare disease. Two examples were discovered in 39 random necropsies on patients over 60 years of age.

Aged↗