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R W BARNES

Publications and source records attributed to R W BARNES.

At least 19 recordsLinked to original sources

PROSTATITIS; AN EVALUATION OF LABORATORY PROCEDURES AND OF THE EFFECTIVENESS OF NITROFURANTOIN.

An estimate of the pus content of prostatic fluid is as good as a count in a counting chamber. There is no correlation between the pus content and the severity of symptoms. Of all of the criteria for making a diagnosis of prostatitis, the pus content of the fluid is the least important. Culture of prostatic fluid is of very little, if any, value for making a diagnosis or guiding treatment. The results of treatment of chronic prostatitis by prostatic massage only, are as good as those obtained by massage plus nitrofurantoin. Acute and subacute prostatitis responded well to nitrofurantoin, and there seemed less likelihood of recurrence when the drug was continued in small doses for four weeks.

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Management of early prostatic carcinoma.

It is important to make a diagnosis of prostatic carcinoma as early as possible, because early treatment gives the best results whether radical prostatectomy is done or endocrine therapy used. Open perineal biopsy is the most accurate method of making a diagnosis. Perineal needle biopsy or the newer approach of transrectal needle biopsy is probably about 75 per cent accurate in making a diagnosis.Ten-year survival with conservative therapy, as determined in a review of a series of cases, was 50 per cent-about the same as that following radical prostatectomy; but the patients with prostatectomy are clinically free of malignant disease whereas the former are not. Radical prostatectomy is indicated in a few selected cases. The results from endocrine therapy begun immediately after diagnosis are significantly better than those from delayed treatment. Orchiectomy and estrogens promise a little longer survival than estrogens alone.

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