Extraskeletal myxoid chondrosarcoma of the epiglottis: case report and review of the literature.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to R W Babin.
Explore the source record for details and available documents.
Two Ptolemaic period mummies underwent head and neck examination including high-resolution tomography and endoscopic rhinoscopy and cranioscopy. The anatomy demonstrated characteristic laryngeal calcification and sexual dimorphism. Pathologic findings consisted of severe dental disease and possible chronic ear disease. Postmortem changes revealed the entrance of the embalmers into the cranial cavity, but raised interesting speculation regarding the method of brain removal.
Three cases of nasal, epidermal, inverted papilloma, one of which involved synchronous carcinoma, were examined at the light and electron microscope level. Case I showed typically stratified squamous epithelial cell fine structure, including interdigitating cell borders with typical desmosome contacts and bundles of intracellular filaments. Epithelial cells of Case II did not have an identical squamous type appearance, they were smoother in outline, lacked extensive cell interdigitation and desmosomes, and were directly apposed to one another. Cells observed in Case III, involving synchronous carcinoma, also failed to reveal extensive stratified squamous epithelial characteristics, but were smooth in outline, lacked extensive interdigitations and desmosomes. On the bases of electron-density, cells in all three biopsies were characterizable as light, intermediate and dark cells. This variation reflects variations in the amount of granular endoplasmic reticulum and non-membrane bound polysomes. Cytological characteristics, including filament formation, filament concentration into bundles, and changes in nuclear structure leading to pyknosis are described. The above data are discussed in terms of their significance and relevance to previous electron microscope studies on various nasal inverted papillomas. It is concluded that fine structure characteristics, as well as light microscopic observations, should be more frequently utilized in identifying malignant as opposed to benign tumors.
Explore the source record for details and available documents.
A two-year prospective study was undertaken to compare acute treatment modalities for peritonsillar abscesses. The most widely used modality, incision and drainage, with subsequent hospitalization for intravenous antibiotics and hydration, was compared with incision and drainage, with subsequent oral antibiotics and oral hydration. The results in 27 randomized patients showed no difference in morbidity, recovery time, or recurrence rate between the two groups. The authors conclude that initial incision and drainage, and oral antibiotics, is an effective, safe and less expensive treatment modality for peritonsillar abscesses. These results suggest that with a compliant patient population, peritonsillar abscesses may be effectively treated in an outpatient setting.
Biopsy material from 50 patients with a known clinical diagnosis of ozena was examined histopathologically. Certain features were invariably seen, including mucosal atrophy, squamous metaplasia, and chronic inflammatory cell infiltrate which suggests a humoral mediated immune process. Histopathologic features allow ozena to be distinguished from chronic non-specific hypertrophic rhinitis, which may have a cell-mediated immune basis underlying its pathogenesis.
A case of junctional nevus of the true vocal cord in a 10-year-old black girl is described. It appears to be the first reported case of lesion in the larynx. The significance of melanocytes in the larynx of a child is discussed.
Explore the source record for details and available documents.
We discuss the case of a 22-year-old black woman who presented with a mass in the left hypotympanicum. Both the pre- and postoperative diagnosis of the lesion was a glomus tympanicum. Histopathologic examination revealed the "tumor" to be a nodule of extramedullary hematopoiesis. Many sickled erythrocytes were also noted within the lesion. A multilingual literature search (English, French, German, Spanish, Portuguese, Italian, and Russian) failed to reveal a documented case of extramedullary hematopoiesis in the hypotympanicum. We assume that the patient's hemoglobinopathy was the cause of her unusual focus of extramedullary hematopoiesis.
An erosive mucosal cyst of the mastoid process is reported. The endodermal lining contained both goblet and nonkeratinizing squamous metaplastic mucosa. Possible causes of cyst formation and its relationship to epidermoid and "motor oil" cysts are discussed.
We have described a family in which the father and three children appear to have an absence of nasal cilia, resulting in inadequate nasociliary clearance, stasis of nasal secretions, and secondary bacterial contamination. This condition should be considered in chronic rhinitis of obscure etiology.
Explore the source record for details and available documents.
A case of traumatic facial neuroma discovered at tympanoplasty is described. Its appearance and histologic findings are compared with those of four previously reported temporal bones with this diagnosis. The clinical significance of such rare lesions appears in their differentiation from more aggressive facial tumors.
The temporal bones from a two year old drowning victim are compared with those of a 13 month old strangulation victim. Tympanomastoid hemorrhage and submucosal edema and petechiae with moderate vascular congestion were characteristic in drowning. Marked congestion with edema but no sign of hemorrhage was found in strangulation. It is concluded that respiratory effort against a closed glottis is not solely responsible for the tympanomastoid hemorrhage known to occur frequently as a result of drowning.
Transsphenoidal encephaloceles are rare congenital anomalies that may be immediately apparent in infants that present with multiple cranial midline defects. They should also be suspected in patients presenting with cerebrospinal fluid rhinorrhea, an epipharyngeal soft tissue mass, a visual defect, or an endocrinologic disturbance, especially when associated with midfacial and optic nerve anomalies. Plain x-ray films of the skull may show absence of the sellar floor and a soft tissue mass; the diagnosis is confirmed by computed tomography scanning. Surgical therapy may be indicated for persistent cerebrospinal fluid rhinorrhea, symptomatic epipharyngeal respiratory distress, or progression of neurological deficits. Two cases of transsphenoidal encephalocele are reported.
Explore the source record for details and available documents.
Arteriovenous malformations of the mandible may present with pulsatile tinnitus, pain, a bruit, loosening of teeth, or intraoral or facial deformation or discoloration. In the absence of these classic symptoms and signs, the unwary surgeon might attempt a limited excision, leading to massive intraoperative hemorrhage. Management includes external carotid as well as selective branch arteriography and preoperative arterial embolization with polyvinyl alcohol sponges and absorbable gelatin. Vessel ligation, mandibular resection, lesion excision, mandibular autografting, and intermaxillary fixation complete surgical treatment.
Explore the source record for details and available documents.