Biomedical subjects
Publications and source records attributed to R W Butner.
A 21-year-old white man with retinitis pigmentosa was found to have an isolated patch of retinal neovascularization. Ocular and systemic evaluation failed to reveal a recognized cause for the neovascularization. This case is felt to represent the unusual association of retinitis pigmentosa and retinal neovascularization.
Adverse reactions were noted in 241 (4.82%) of 5,000 consecutive intravenous fluorescein angiographies of the retina. The most frequent adverse reactions were nausea (2.24%), vomiting (1.78%), and urticaria/pruritus (0.34%). No life-threatening reactions were noted. No significant difference in the rate of adverse reactions was found when angiography using 10% fluorescein was compared with angiography using 25% fluorescein.
The causes of 653 cases of spontaneous vitreous hemorrhage were evaluated. The four most common causes, accounting for over 84% of the cases, were diabetic retinopathy (34.1%), retinal break without retinal detachment (22.4%), rhegmatogenous retinal detachment (14.9%), and retinal vein occlusion (13.0%). Other diagnoses accounting for a significant number of cases of spontaneous vitreous hemorrhage included posterior vitreous detachment, retinal vasculitis, senescent macular degeneration, intraocular tumor, and retinopathy of prematurity. The remaining, uncommon, diagnoses accounted for less than 5% of the cases.
The records for a group of 2,054 patients who had undergone surgery fur rhegmatogenous retinal detachment with macular involvement were analyzed to ascertain the relative influence of the following five specific factors on postoperative visual acuity: (1) patient age, (2) degree of preoperative macular elevation, (3) duration of preoperative macular detachment, (4) extent of retinal detachment, and (5) drainage of subretinal fluid. Increasing patient age, increasing preoperative macular elevation, increasing duration of macular detachment, and increasing extent of retinal detachment were all found to be associated in general with decreasing postoperative visual acuity. Drainage, or nondrainage, or subretinal fluid appeared to be unassociated with postoperative visual acuity.