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R W Dhurandhar

Publications and source records attributed to R W Dhurandhar.

6 recordsLinked to original sources

Pseudohysteresis in a universal AV sequential pacemaker.

We describe pacemaker pauses and pseudohysteresis resulting from sensing of retrograde P waves in a patient with an implanted AV sequential universal pacemaker. Although retrograde P waves are usually followed by a ventricular spike and therefore create the possibility for "endless loop tachycardia," in our patient some retrograde P waves which followed premature ventricular contractions or junctional beats produced pacemaker pauses. The reason for the occurrence of this phenomenon is that the sum of the VA conduction time and the AV delay is shorter than the pacemaker's hardware rate limit. Therefore, the ventricular spike that should follow the retrograde P wave is inhibited. In the pacemaker used by us, the atrial refractory period is only initiated by an atrial event, allowing the pacemaker to sense retrograde P waves occurring after premature junctional or ventricular depolarizations. Although no therapy is needed for the phenomenon described, it is important to understand its true significance and to avoid unnecessary surgical procedures.

Aged

Pseudo second degree atrioventricular block with bradycardia. Successful treatment with quinidine.

Pseudo second degree atrioventricular block resulting from blocked His premature beats was successfully treated with quinidine. The diagnosis was proved by His bundle electrogam which showed both blocked and conducted His premature beats. The blocked His prematures produced second degree atrioventricular block by making the atrioventricular junction refractory. Quinidine abolished both conducted and blocked His extrasystoles. There has been no recurrence of arrhythmia during a one-year follow-up.

Bradycardia

Ventricular tachycardia-flutter associated with disopyramide therapy: a report of three cases.

Three patients developed episodes of ventricular tachycardia and/or flutter-fibrillation while receiving disopyramide (Norpace). Syncope was the presenting complaint in all of them. The arrhythmias did not recur after disopyramide was discontinued. The Q-T interval was markedly prolonged in all three patients. One patient developed syncope associated with both quinidine and Norpace therapy. It is postulated that disopyramide, like quinidine, may provoke ventricular flutter-fibrillation in sensitive patients by similar mechanisms.

Aged