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Biomedical subjects

R W Hertle

Publications and source records attributed to R W Hertle.

52 records · Page 3Linked to original sources
PubMed1988

Effects of retinal image stabilization in acquired nystagmus due to neurologic disease.

We studied the effects of variable amounts of artificial retinal image stabilization (RIS) upon oscillopsia and visual acuity in eight patients with acquired nystagmus due to neurologic disease. We measured horizontal and vertical eye movements with the magnetic search coil technique and used these electronic signals to control the position of a visual stimulus on a screen in front of the patient. We also used an optical device to stabilize images of the real world upon the retina. During electronic stabilization, RIS was progressively increased until oscillopsia was abolished; this was achieved in all eight patients and corresponded to retinal image drift of 5 degrees/sec or less. In five patients with downbeat nystagmus, further increases in RIS caused the oscillopsia to reappear, but in the opposite direction. Electronic stabilization also improved visual acuity in four of five patients; the limitation of improvement could be related to coexistent visual system defects. Using electronic feedback, we could measure the range of RIS that any individual required to abolish oscillopsia; from this measurement, the components of the optical device that were best suited to provide a stable field of vision could be calculated.

Eyeglasses↗
PubMed1981

Visual acuities in infants with congenital cataracts operated on prior to 6 months of age.

Seven infants with complete bilateral cataracts were operated on and fitted with extended-wear silicone contact lenses. The infants were matched to 16 normal control subjects. A modified preferential looking technique was used to assess visual acuity; the Bayley Scale of infant Development was administered to measure psychological development. Of the seven infants with cataracts, those operated on prior to 8 weeks of age seemed to have normally developing vision. All others showed a substantial visual lag when compared with the control group. Bayley scores for infants operated on early (before 8 weeks) fell within the range of normal variability. The infants operated on later demonstrated a statistically significant lag in development. Also, a pendular nystagmus was noted in those infants with cataracts who were operated on later.

Age Factors↗
PubMedDate not supplied

Examination and refractive management of patients with nystagmus.

Patients with nystagmus present unique challenges to the ophthalmologist. These patients can be difficult to examine and refract. Treatment options to improve vision or reduce disturbing visual symptoms are limited, which is disappointing to the patient and frustrating to the clinician. This paper will provide the clinician with one method of clinically organizing nystagmus, describe the patients who may benefit from optical treatments, and discuss the methodology used in their implementation. Techniques that will be discussed include patient examination and objective and subjective refraction. Optical treatments discussed include spectacles, prisms, contact lenses, and retinal image stabilization.

Contact Lenses↗
PubMedDate not supplied

Visual loss in patients with craniofacial synostosis.

We reviewed the ocular findings in patients with cranial stenosis, who were seen in the Craniofacial Clinic at The Children's Hospital of Philadelphia, to determine the prevalence, pattern, and etiology of visual loss. There were 15 patients with Apert syndrome, 25 patients with Crouzon syndrome, and 18 patients with other forms of craniofacial synostoses. Visual loss occurred in 17 eyes of 11 patients with Apert syndrome, 14 eyes of 11 patients with Crouzon syndrome, and 12 eyes of 8 patients with other craniofacial synostosis syndromes. Refractive errors and strabismus were present in the majority of these patients. Amblyopia due to strabismus, ametropia, or ptosis was the major reason for visual loss in all three groups of patients. Structural abnormalities contributed to loss of vision in six eyes.

Craniofacial Dysostosis↗
PubMedDate not supplied

Epibulbar squamous cell carcinomas in brothers with Xeroderma pigmentosa.

We report two brothers aged 6.6 and 5 years old with the De Sanctis-Cacchione variant of Xeroderma Pigmentosa. They had typically severe skin, and ocular and neurologic involvement. Both had epibulbar squamous cell carcinomas. The oldest presented with a large, invasive, epibulbar mass of the left eye which required enucleation. He also had an invasive squamous cell carcinoma of the right lower lid. The younger brother presented with a smaller papillomatous lesion at the medial limbus of the right eye. After removal, this was found to be squamous cell carcinoma in-situ. Flow cytometry done on the tumors revealed diploidy. The case descriptions, histopathology, and discussion of ocular manifestations are presented.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Insertion site dynamics and histology in a rabbit model after conventional or suspension rectus recession combined with ipsilateral antagonist resection.

We have used a rabbit model to study insertion movement, rotational forces, disinsertion forces, and histology of the surgically created insertion site after recession of the inferior rectus (IR) using a conventional (CONV) or suspension (SUS) technique combined with an ipsilateral superior rectus (SR) resection. During the 5-week observation period, the CONV and SUS recessed IR showed an initial posterior movement followed by an anterior movement while all resected SR had an initial posterior movement which remained stable. SR rotational forces increased and IR remained constant throughout the 5-week observation period. There were no rotation force differences between the SUS and CONV recession techniques. Disinsertion forces showed an initial large decrease in force followed by a gradual increase to preoperative levels by 3 postoperative weeks. Disinsertion force differences between the CONV and SUS recessions were observed for 5 weeks after surgery. Histologic analysis showed a delayed inflammatory response on the SUS recession compared to the CONV recession and at the middle of the insertion compared to the poles which was minimized by 3 weeks after surgery.

Animals↗
PubMedDate not supplied

The intraoperative oculocardiac reflex as a predictor of postoperative vaso-vagal responses during adjustable suture surgery.

Adjustable suture surgery has become a popular method of strabismus correction in those cases in which results are less predictable, such as reoperations, thyroid ophthalmopathy, and blind eyes. Complications related to adjustable strabismus surgery are, in general, no different than those related to standard surgical techniques. We noticed a subgroup of patients who experienced significant vaso-vagal responses (V-VR) during postoperative adjustment and sought to discover a method of identifying these patients prior to adjustment. Sixty patients were studied prospectively from July 1991 to July 1992. All patients had surgery under general anesthesia and were adjusted 24 hours later. A positive oculocardiac reflex (OCR) occurred when a 10% or greater intraoperative change in heart rate was associated with traction on an extraocular muscle. A positive V-VR postoperatively consisted of one or more subjective findings (dizziness, light-headedness, nausea, or body temperature changes), and two or more objective findings (10% or greater change in heart rate, hypotension, pallor, diaphoresis, vomiting, disorientation, or loss of consciousness). Variables studied for predictive value included OCR, age, sex, strabismus type, previous surgery, muscle adjusted, and systemic disease. Twenty-five patients (41.6%) had a positive V-VR during adjustment. Twenty-seven patients (45%) had a positive OCR. Eighty-five percent of patients with a positive OCR and 9% of patients with a negative OCR had a positive V-VR. Younger patients were also more likely to have a positive V-VR. A positive intraoperative OCR under general anesthesia during strabismus surgery is highly predictive of a postoperative V-VR during planned adjustment.

Adolescent↗
PubMedDate not supplied

The use of hyaluronic acid during adjustable suture surgery.

We prospectively studied the force required to move an extraocular muscle after adjustable suture surgery with and without the perioperative use of hyaluronic acid (Healon). The 15 muscles that received hyaluronic acid averaged 15.0 g of force to move the muscle 2.0 mm which was significantly different than the average force of 36.15 g required for the 13 control muscles. The decreased force required to adjust the muscle along with potential antiinflammatory properties of hyaluronic acid make this a useful adjunct during adjustable suture surgery.

Humans↗
PubMedDate not supplied

Clinical characteristics of surgically treated adult strabismus.

BACKGROUND: Strabismus is present in approximately 4% of the population with most forms becoming clinically evident in infancy and childhood. Adult strabismus, including that resulting from recurrent childhood deviations, varies in etiology, presentation, symptomatology, and response to treatment. This report is intended to prospectively characterize adults who required surgical correction of their strabismic deviation. METHODS: Beginning in 1991, a prospective computerized database was collected that contained all clinical, laboratory, and surgical information on the adult ocular motility service at the Scheie Eye Institute and The Children's Hospital of Philadelphia (Philadelphia, Pa). Analysis of those patients who underwent surgical correction of their strabismus is included in this report. Demography, clinical characteristics, and surgical procedures including results were analyzed separately in adults with their strabismus beginning before visual maturation (BVM) (9 years of age) and after visual maturation (AVM). RESULTS: A minimum of 6 months and average of 1.8 years follow up is reported on 262 procedures in 255 patients with an average age of 37 between January 1991 and January 1996. Sixty-two percent of patients had their strabismus onset BVM. Fifty-one percent of BVM patients and 80% of AVM patients had incomitant deviations. Adjustable suture surgery was performed on 97% of all patients, with 28% of BVM and 57% of AVM patients having multiplanar surgery. Successful motor alignment was achieved in 85% of all patients after one surgical procedure. Sensory success was achieved in 81% of all AVM patients and 25% of all BVM patients. Subjective success was 94% in both groups of patients. CONCLUSIONS: Numerous differences exist between childhood and adult strabismus characteristics and response to surgery. Although strabismus surgery is effective, differences in results reflect the varied physiology regarding etiology, pathophysiology, and symptomology. Classification into AVM and BVM groups will provide continued clarity for future studies.

Adolescent↗
PubMedDate not supplied

Infantile esotropia.

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Decision Making↗