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Biomedical subjects

R W Meyer

Publications and source records attributed to R W Meyer.

9 recordsLinked to original sources
PubMed2000

Mechanical comparison of a distal femoral side plate and a retrograde intramedullary nail.

OBJECTIVE: To compare quantitatively the axial and torsional stiffness of a retrograde intramedullary nail and a fixed angle screw side plate in treating a supracondylar femur fracture in osteopenic femora. To determine the modes of failure of an intramedullary nail and a side plate under axial loading. DESIGN: Matched pair cadaveric study. SETTING: Orthopaedic biomechanics laboratory. PATIENTS AND OTHER PARTICIPANTS: Eleven matched pairs of preserved human femora were selected. The cadaveric specimens were harvested from relatively elderly donors with an average age of 75.6 years, which represents the principal population at risk for poor fracture fixation. INTERVENTION: The eleven matched pairs were osteotomized to simulate segmental structural defects in the supracondylar region. One femur of each matched pair was fixed with an intramedullary nail, and the contralateral femur was fixed with a side plate. MAIN OUTCOME MEASURES: Axial and torsional stiffness values. Axial modes of failure. RESULTS: The intramedullary nail axial stiffness was 14 percent (p = 0.04) less and torsional stiffness was 17 percent (p = 0.05) less than that provided by the side plate. The axial failure of the intramedullary nail occurred distally, allowing the hardware to protrude into the articular space. The side plate also failed distally by displacing the condylar screw into a varus angulation. CONCLUSION: The mechanical advantages favor the use of the side plate if fixation stiffness is essential. The axial mode of failure occurs distally for both fixation devices.

Aged↗
PubMed1985

Mechanical ventilation for acute postoperative respiratory failure after surgery for bronchial carcinoma.

From 1978 to 1982 365 patients were treated surgically for bronchial carcinoma. Lobectomy was performed in 250 and pneumonectomy in 115. Sixteen (4.4%) needed mechanical ventilation for acute respiratory failure. Six out of eight with a lobectomy, but only two out of eight with a pneumonectomy, survived initially. Of these eight survivors, five died from recurrent malignancy within a year but three were alive and well at two years. The complications leading to acute respiratory failure were unpredictable in most patients. Improving techniques of mechanical ventilation and intensive care may lead to better results in the future.

Aged↗
PubMedDate not supplied

A differential staining method to identify lignified and unlignified tissues.

We investigated the use of safranin O and astra blue dissolved in ethyl alcohol as differential stains to distinguish between lignified and unlignified tissues in microtome sections of tension and normal wood of sugar and red maple. Normal wood was used as a control for the histochemical analysis. Lignified and unlignified tissues were found in the same section for both tension and normal wood of each species. These results were confirmed in unstained samples using ultraviolet light. Unlignified libriform fibers were detected using both techniques. Libriform fibers did not fluoresce in UV light, although fluorescence was observed in some of the cell corners. The astra blue in ethyl alcohol and the UV wavelength we used differentiated syringyl from guaiacyl lignins. Ethyl alcohol solutions of these dyes provide an effective and reliable method to distinguish lignified and unlignified tissues.

Acer↗
PubMedDate not supplied

Comparison of various icing times in decreasing bone metabolism and blood flow in the knee.

In a previous study we used technetium-99m bone scans to show that cooling a knee for 20 minutes with a standard ice wrap will decrease soft tissue blood flow by a mean of 26%, and skeletal blood flow and metabolism by 19%. The present study examined the effects of shorter and longer icing periods to determine minimum cooling time for a measurable and consistent decrease, and time to produce maximal decrease within a safe period of icing (< 30 minutes). Thirty-eight subjects were studied. An ice wrap was applied to one knee for an assigned time (5, 10, 15, 20, or 25 minutes). Triple-phase bone scans of knees were obtained; mean percentages of decrease in the iced knee for each of the five time groups at each of the three phases of the bone scan were calculated and compared. Mean decreases of 11.1% in soft tissue blood flow, and 5.1% in skeletal metabolism and blood flow were measured at 5 minutes; maximums of 29.5% and 20.9%, respectively, were obtained at 25 minutes. A small but consistent decrease in soft tissue blood flow and skeletal blood flow and metabolism in a knee appear to be obtained with as little as 5 minutes of ice application. This effect is time-dependent and can be enhanced three- to four-fold by increasing the ice application time to 25 minutes.

Adult↗