Biomedical subjects

R W Short

Publications and source records attributed to R W Short.

4 recordsLinked to original sources

PubMed2006

Effects of moisturization on epidermal homeostasis and differentiation.

Moisturizers are commonly used for routine skin care. This study assessed the effects of a moisturizer on barrier function, epidermal architecture, keratinocyte proliferation, and physiological regulation of the epidermis in photoaged but otherwise normal skin. Fifteen women with moderately photoaged forearms were treated twice a day for 4 weeks with a moisturizer containing dimethicone and glycerine. Baseline and post-treatment transepidermal water loss (TEWL) and ipsilateral forearm biopsies were obtained. Epidermal thickness, melanin levels, keratinocyte proliferation, and expression of keratins were evaluated. Induction of keratins 6 and 16, commonly associated with keratinocyte proliferation and wound healing, was observed. Epidermal thickness increased by 0.019 mm (P = 0.005), barrier function improved (TEWL decreased by 13%) and melanin intensity decreased (P = 0.004). Even nonxerotic, photoaged skin may appear younger, benefiting structurally and functionally from routine use of moisturizers containing dimethicone and glycerine.

Adult↗

PubMed2003

Time-dependent electron thermal flux inhibition in direct-drive laser implosions.

We simulate direct-drive CH target implosions with square laser pulses by a one-dimensional Fokker-Planck solver combined with a hydrodynamic code, and compare the results with those simulated by the flux-limited Spitzer-Härm model. We find that the electron thermal flux inhibition is time dependent, resulting in longer density scale length, larger laser absorption, and smaller growth of Rayleigh-Taylor instability. The time of peak neutron production calculated from Fokker-Planck simulations agrees with experiments for both 1-ns and 400-ps pulses.

Journal Article↗

PubMed2003

Multibeam effects on fast-electron generation from two-plasmon-decay instability.

Experiments with multiple laser beams have been carried out in both spherical and planar geometry to study two-plasmon-decay instability, the predominant source of suprathermal electrons in direct-drive inertial confinement fusion experiments. These electrons are observed using the hard x rays generated through electron-target interactions. The experiments show for the first time that the total overlapped intensity governs the scaling of the suprathermal-electron generation regardless of the number of overlapped beams, in contrast to conventional theories that are based on the single-beam approximation.

Journal Article↗

PubMed2002

Multibeam stimulated brillouin scattering from hot, solid-target plasmas.

We report on multibeam, laser-plasma interaction experiments in plasmas relevant to future direct-drive-ignition experiments. Six interaction beams are incident on preformed plasmas containing critical density. Stimulated Brillouin scattering (SBS) shows strong evidence of electromagnetic wave seeding of side- and backscattering. The data are also consistent with shared ion waves driven by the six symmetrically arranged interaction beams. Early SBS quenching is observed and attributed to the hydrodynamics of the plasma.

Journal Article↗