Biomedical subjects
R W Wahl
Publications and source records attributed to R W Wahl.
Fine-needle aspiration of metastatic sacrococcygeal myxopapillary ependymoma.
A 45-yr-old white woman with a 24-yr history of sacrococcygeal myxopapillary ependymoma developed a large metastasis of scalp and skull diagnosed as metastatic ependymoma on fine-needle aspiration, based on cytologic features, histologic pattern in cell block fragments, and a positive reaction with the glial fibrillary acidic protein immunoperoxidase study. The fine-needle study obviated the need for biopsy in this case, for which a surgical approach was considered to be inappropriate due to the extent of the process demonstrated by various imaging techniques.
Mycosis fungoides of thyroid diagnosed by fine needle aspiration.
Fine needle aspiration of a poorly defined thyroid nodule in a patient with mycosis fungoides revealed convoluted mononuclear cells consistent with involvement by mycosis fungoides. I have briefly reviewed the literature on extracutaneous involvement, and discussed the potential usefulness of fine needle aspiration studies in diagnosing visceral or lymphatic mycosis fungoides.
Malignant melanoma presenting as peritoneal effusion.
Explore the source record for details and available documents.
Multiple ganglioneuromas of the central nervous system.
Explore the source record for details and available documents.
Curschmann's spirals in pleural and peritoneal fluids. Report of 12 cases.
A limited prospective study of 334 peritoneal and pleural fluids demonstrated Curschmann's spirals in 12 specimens, a prevalence of 1 in 28 cases. Nine of these 12 specimens were peritoneal washings, 2 specimens were pleural fluids, and 1 specimen was a peritoneal dialysis fluid. The fluids came from nine women and three men. Both pleural fluids were from men (one with a history of lung adenocarcinoma and one with probable collagen vascular disease). The peritoneal dialysis fluid was from a man with renal failure. Seven of the nine women with peritoneal washing specimens had gynecologic cancer; only one had evidence of serosal involvement by neoplasm at the time of the peritoneal washing. Tissue, including serosal surfaces, was available for examination in 10 of the 12 cases. The study indicates that Curschmann's spirals are a relatively common finding in peritoneal and pleural fluids, particularly in peritoneal washings. Mucin-producing epithelium or involvement of serosa by malignant neoplasm is not necessary for the phenomenon to take place. The feature common to all the cases in which tissue was available for review was the presence of myxoid degenerative changes of the serosal and subserosal fibrous connective tissue.
Fine needle aspiration study of metastatic mixed adenosquamous carcinoma of the renal pelvis. A case report.
The findings in a fine needle aspirate of a psoas area metastasis from a mixed adenosquamous carcinoma of the renal pelvis are presented. The primary renal tumor is apparently the fourth such case reported in the literature; the pathogenesis of such tumors is briefly reviewed. The value of fine needle aspiration in excluding a clinically suspected abscess and in allowing a specific diagnosis of malignancy is emphasized.
Chlamydia, repair and intraepithelial neoplasia.
Explore the source record for details and available documents.
Malacoplakia of the uterine cervix: report of two cases.
Two cases of malacoplakia involving the uterine cervix are reported. Lesions of the genital tract caused by this uncommon granulomatous reaction may suggest malignancy clinically and may present with vaginal bleeding. Cytologic findings in cervical smears from both patients included inflammation and abundant histiocytes. The characteristic finding is the Michaelis-Gutmann body, which can be identified in cervical smears, especially with the use of PAS or von Kossa stain. Gram-negative bacilli may be cultured from the tissue or identified on Gram's stain. Antibiotics are probably effective in eradication, as is surgical excision.