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Biomedical subjects

R Weiske

Publications and source records attributed to R Weiske.

18 recordsLinked to original sources
PubMed1994

Measurement of mandibular bone density after iliac crest grafting.

Nonvascularized and microsurgically revascularized iliac bone grafts used for mandibular reconstruction behave differently during healing. Quantitative computer tomography (QCT) was used to investigate these differences with respect to mineralization and macrostructure of the grafts after a period of adequate functional loading. It was shown that in nonvascularized grafts, reactive sclerosis occurs, as a sign of an irregularly reparative metaplastic process and mineralization. In comparison with the intact iliac crest, the bone density of the graft was markedly increased. The microsurgically revascularized grafts, however, showed retention of structural differentiation into homogeneous cancellous bone, and a smoothly demarcated cortex with essentially unchanged bone density. Possible explanations of these differences are discussed.

Absorptiometry, Photon↗
PubMed1993

Quantitative computed tomography--a new method in the assessment of autologous augmentation of the mandible.

Following autologous alveolar ridge augmentation with microsurgically revascularized iliac crest segments, quantitative computed tomography was used for the first time to examine mandible and graft. The results are shown by the example of 2 cases. Sufficient mineralization of the graft could be demonstrated macromorphologically as well as by means of bone densitometry. Insignificant variations of the grade of mineralization in the separate segments of the graft may exist, caused by the operation. There were no distinct reactive scleroses indicating an extensive process of transformation and adaptation.

Alveolar Ridge Augmentation↗
PubMed1991

[Lung involvement in Wegener's granulomatosis: results of studies with high resolution computerized tomography].

The report covers experience of high resolution computerized tomography examinations of eight patients suffering from pulmonary manifestations of Wegner's granulomatosis. Classification of the lesions according to Murata's scheme is of no diagnostic benefit. The only findings that are diagnostic are cavitary lesions. Cavitation was found in five cases in this series.

Adolescent↗
PubMed1990

[The diagnosis of pulmonary manifestations of Wegener's granulomatosis using high-resolution computed tomography].

7 patients presenting with pulmonary manifestation of Wegener's granulomatosis are discussed. They were examined via high-resolution computerised tomography. In 5 cases pulmonary nodules with or without cavitation could be detected. 4 patients showed intrapulmonary opacities of the ground glass type; in one case, a reticular intrapulmonary infiltration was seen.

Adolescent↗
PubMed1990

[Contrast-enhanced CT of the mediastinum in lymph node diagnosis].

In mediastinal lymphoadenopathy diagnostic problems arise if lymphomas are of the same density as cardial or vascular structures. For this reason, CT based on contrast enhancement must definitely ensure a significantly greater enhancement of vascular structures than of non-vascular ones during the entire scan period. We studied 4 groups of 20 patients each employing standardised CT examinations employing 100 ml. contrast medium in different concentrations (200 and 300 mg. iodine/ml., respectively) and an injection flow rate of 0.7 and 2.0 ml/s. The results show that higher iodine concentrations produce a significantly greater enhancement in the aorta than a lower iodine concentration independent of the flow rate. Although a lower flow rate slightly delayed the enhancement increase, this was nevertheless higher than 60 HU within a period of 4 minutes. Hence, we recommend to perform contrast enhanced CT of the mediastinum using lower flow rates (0.5-1.0 ml/s.) and a higher contrast medium concentration (300 mg. iodine/ml.).

Adult↗
PubMed1988

[Destructive non-infectious spondyloarthropathy in chronic renal insufficiency].

The aetiology of destructive non-infectious spondylo-arthropathy has not been completely elucidated. Deposition of various crystals and of amyloid (beta-2-microglobulin) is a possible cause of this condition which has not been considered previously. The appearances of destructive non-infectious spondylo-arthropathy are illustrated by seven patients with renal insufficiency and on chronic haemodialysis; these were examined by conventional radiographs and by CT. It is possible to distinguish between the complete condition (five patients) and an early form (two patients). The differential diagnosis of the changes in the vertebral end-plates are discussed with reference to three further patients with chronic renal disease and on dialysis.

Adult↗
PubMed1987

[Hyperostotic bone changes of the spine in diabetes mellitus].

The diffuse idiopathic skeletal hyperostosis, especially with manifestation at the vertebral column, is often associated with metabolic disorders, such as diabetes mellitus or hyperuricaemia. Clinical, pathogenetic and radiological aspects are discussed. Routine thoracic x-ray give important informations on the diagnosis of this osteoplastic diathesis.

Diabetes Mellitus↗
PubMed1986

[Diagnostic problems of alveolar cell carcinoma].

The clinical and radiological symptoms and differential diagnosis of four out of seven cases of alveolar cell carcinomas of the lung, which were observed during the last years, have been compared. Some characteristics are shown, which make the differentiation possible between tuberculosis, sarcoidosis, chronic carcinogenic pneumonia and interstitial lung diseases. Early diagnosis by histological investigation of cells from sputum or from bronchial secretion and by needle biopsy seems possible. During the earliest stage alveolar cell carcinoma can be cured by surgery.

Adenocarcinoma, Bronchiolo-Alveolar↗
PubMed1986

[Lung complications in AIDS].

A short description of epidemiologic and clinical facts correlated with the acquired immunodeficiency syndrome (AIDS) is followed by a report on the manifestation of pulmonary infections mostly effected by Pneumocystis carinii. Two examples out of four cases will demonstrate the radiographic appearance of the Pneumocystis carinii pneumonia and clinical data. Only in rare cases does it seem possible to reduce the fatal outcome by early diagnosis.

Acquired Immunodeficiency Syndrome↗
PubMed1986

[Differential diagnosis of posttraumatic pulmonary infiltrates].

The differential diagnostic value of radio-morphological criteria as well as the prognostic fate of pulmonary infiltrates was studied in 377 patients presenting with major traumatic infiltrates in the thorax. We found that neither the character of the infiltrates (alveolar/interstitial) nor their morphology (homogeneous/inhomogeneous, dense/dispersed) were suitable for differentiation owing to extensive overlapping. The localization of infiltration, otherwise a good diagnostic indicator, provided little reliable information either. Conversely, the time course of the infiltrates, especially the time of their first visualization, turned out to be the only criterion usable for differentiation. Patients studied immediately after or within hours of an accident exhibited contusion and aspiration infiltrates, with a delay of 1-2 days the infiltrates were mostly caused by fat embolism and ARDS, while pneumonic infiltrates appeared after at least 2 days. The course of the infiltrates further permits certain diagnostic conclusions, but it is of little help in establishing the primary diagnosis and may be usable for corrections at best. The relatively high specificity of the criterion "first appearance of infiltrates" may be reduced by the coincidence of several lesions or ensuing complications. In retrospect, it seems that a reliable radiological differential diagnosis of posttraumatic infiltrates is not possible, but satisfactory results can be achieved if specific X-ray criteria are viewed against an extensive clinical back-ground.

Adult↗
PubMed1985

[Information value of x-ray computed tomography for the detection and control of spondylitis].

The information content of early bone changes in computed tomography (CT) of pyogenic non-tuberculous spondylitis and spinal tuberculosis is analysed. The CT findings are compared with conventional x-ray images including tomography. In 3 of 16 patients no indications of osteomyelitis were found by conventional x-ray images, whereas CT revealed paravertebral soft tissue swelling or abscesses and osteolysis and thus established the diagnosis of spondylitis. In one patient the process caused neurologic symptoms by extending into the epidural space. The contributions of CT to the diagnosis of spondylitis are to delineate the extent of soft tissue swelling, to detect small defects in the vertebral bodies, to exclude disc involvement, and to differentiate inflammations and other destructive changes. CT can be used for fine needle localization and aspiration of tissue or pus for histological or bacteriological investigations to establish the pathological diagnosis.

Adult↗