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Biomedical subjects

R Wickenhöfer

Publications and source records attributed to R Wickenhöfer.

6 recordsLinked to original sources
PubMed1992

[The palliative treatment of primary hepatocellular carcinoma by chemoembolization].

16 patients (12 men, 4 women; mean age 62.8 +/- 9.8 years) with inoperable advanced hepatocellular carcinoma were treated palliatively by chemoembolization. 50 mg/m2 epirubicin, 30 mg/m2 cisplatin, 8 ml fatty acid ethyl ester of iodinated papaver oil and 10 ml nonionic contrast medium were injected under fluoroscopy into the proper hepatic artery. Partial remission was achieved in 10 patients after a median of 4 months. In 4 patients there was no change in the morphological and biochemical findings, in two others the tumour progressed, i.e. an overall response rate of 62.5%. The median survival time was 9 months. There were no serious complications ascribable to the treatment. Chemoembolization is a palliative treatment with few side effects which can also be effective in prolonging survival time in advanced hepatocellular carcinoma.

Aged↗
PubMed1992

[The results of the chemoembolization of advanced hepatocellular carcinomas. The effect on the survival times, morphological findings and tumor markers].

Chemoembolization is a well-recognized therapeutic procedure in the treatment of stage I and stage II hepatocellular carcinoma (HCC). Until now it is rarely used in the treatment of stage III HCC. In a prospective study we analysed the efficacy and the side effects of chemoembolization in 16 patients with stage III HCC. Chemoembolization was performed with an emulsion of lipiodol, 4-epirubicin and cisplatinum. All patients tolerated the treatment without remarkable complications. With 9 months the median survival rate was considerable higher than the survival rate of untreated patients and of patients treated with systemic chemotherapy or with local perfusion.

Aged↗
PubMed1990

[Long-term experience with a PACS subsystem].

Our experiences with a PACS-Subsystem have shown, that it would be more usefull and less expensive, first to install digital archiving systems in single areas. After a certain time of errorfree working the subsstems should be integrated into a superior information system. Fast data networks and userfriendly viewing stations are a basic requirement. Common standards of archiving, independent of the manufacturer, should be considered.

Angiography, Digital Subtraction↗
PubMed1983

[Renin-angiotensin system under extracorporeal circulation during heart valve surgery].

Angiotensin I (A I), angiotensin II (A II) and the activity of angiotensin-converting enzyme (ACE) were measured in 15 patients undergoing cardiopulmonary bypass for mitral or aortic valve replacement. During cardiopulmonary bypass A I, A II, A I/II ratio and arteriovenous A II--difference decreased markedly, whereas the activity of ACE fell only during a small 15 min period after start of extracorporeal circulation. Possible reasons for these effects are discussed.

Angiotensin I↗