Biomedical subjects

R Wojczys

Publications and source records attributed to R Wojczys.

9 recordsLinked to original sources

PubMed1997

Effect of inferior mesenteric artery ligation on the healing of colonic anastomoses in rats.

OBJECTIVE: To evaluate the healing of single-layer end-to-end colonic anastomoses in rats in which the inferior mesenteric artery had been ligated. DESIGN: Controlled experiment. SETTING: Medical school, Poland. ANIMALS: 20, 2-month-old inbred Buffalo rats (n = 10 in each group). INTERVENTIONS: Laparotomy with ligation of the inferior mesenteric artery (laparotomy alone in the control group), followed by segmental colonic resection and primary anastomosis 24 hours later, and resection of the anastomosis 4 days later. MAIN OUTCOME MEASURES: Degree of contamination and inflammation of peritoneal cavity and histological evaluation of the anastomosis. RESULTS: No animal died and no anastomosis leaked. There were no histological differences in the extent of early healing between the groups. In 2 animals in the experimental group pathogens were grown from the peritoneal culture (Escherichia coli and Bacteroides fragilis in each case). CONCLUSION: High ligation of the inferior mesenteric artery had no deleterious effect on the healing of colonic anastomoses in rats.

Anastomosis, Surgical↗

PubMed1997

[Pancreatoduodenectomy by Whipple's method--a method of dealing with the pancreatic stump].

Different methods of pancreatic stump management are possible to perform after pancreaticoduodenectomy. The group of 24 patients after pancreaticoduodenectomy with pancreaticojejunostomy, pancreaticogastrostomy and occlusion of the pancreatic duct by Neopren or Ethiblock were analysed. According to the literature and own results pancreatogastrostomy or occlusion of the pancreatic duct seems to be the safer procedure, but sometimes the choice is made intraoperatively.

Anastomosis, Surgical↗

PubMed1997

[Bile duct injuries and surgical reconstruction of their sequelae in patients surgically treated for cholelithiasis].

27 patients operated for bile duct injuries as a complication of cholecystectomy were analyzed. The methods of surgical management in "fresh" bile duct injuries and delayed complications such as stenosis of bile ducts or anastomosis and recurrent cholangitis were discussed. Mucosa to mucosa, Roux-en-Y anastomosis, without splinting drains seems to be the best way to restore bile flow to digestive tract.

Adult↗

PubMed1997

[Restorative proctocolectomy in treatment of ulcerative colitis and familial polyposis].

The results of surgical management (restorative proctocolectomy) in 15 patients operated on for familial polyposis and ulcerative colitis were presented. The comparison of ileo-anal, hand-sewn anastomosis with endorectal mucosectomy and double-stapled ileo-rectal anastomosis indicates both methods equally useful in surgical practice. In all patients J-pouch was created. The choice of anastomosis should be carefully considered before operation in every patient, but sometimes changed intraoperatively.

Adenomatous Polyposis Coli↗

PubMed1992

[Knee joint cyst].

Ninety cases of knee joint cysts were treated surgically. This included 50 patients with rheumatoid arthritis, 22 patients with degenerative-deforming changes, ten children with true cysts, and eight ones with post-traumatic cysts. Double-contrast X-ray examination with Lipiodol Ultra-fluid and air is of the best diagnostic value. All cases of knee joint cysts were treated surgically with a careful plastic closure of cyst gate. For this purpose the authors used the arcus tendon of the semi-membranous muscle. In cases of rheumatoid arthritis and degenerative changes cyst removal was preceded by synovectomy of the knee joint. Early and remote were good, no recurrence was observed.

Adolescent↗

PubMedDate not supplied

[Cholesterol and its lipoprotein fraction in serum and bile of patients with cholelithiasis].

Total cholesterol, HDL, LDL and triglycerides were assayed in the blood serum and bile from the liver and gallbladder of both normal individuals and patients with cholelithiasis. It was found that all assayed parameters are significantly higher in patients with cholelithiasis. An increase in total cholesterol and HDL was seen in the bile from the liver whereas an increase in the level of unstable LDL by about four fold with simultaneous decrease in HDL level were found in the bile from the gallbladder. These differences in lipoprotein fractions level in patients with cholelithiasis indicate systemic disorders in cholesterol metabolism.

Adult↗

PubMedDate not supplied

Helicobacter pylori in experimental acute and chronic gastric and duodenal ulcer in Buffalo [correction of Bufallo] rats.

The experiment was performed using inbred Buffalo rats to confirm the coincidence between peptic, gastric and duodenal ulcer and Helicobacter pylori infection. The results suggest an unquestionable meaning of Helicobacter pylori appeared to be as strong ulcerogenic factor in rats as ligation of pylorus and diffusely administrated histamine.

Acute Disease↗

PubMedDate not supplied

Pancreatic islet cell hyperplasia associated with experimental ulcerative colitis in rats.

Ulcerative colitis in Buffalo rats was induced by acetic acid introduced into sigmoid colon. In specimens of the colon and head of the pancreas obtained via laparotomy after seven-day colitis ulcerosa and simultaneously the pancreatic islet cell hyperplasia were histologically observed. Further investigations, especially immunological studies, of these amazing findings are necessary to elucidate the mechanism of the abore relationship.

Animals↗

PubMedDate not supplied

Liver involvement and its course in experimental colitis in rats.

BACKGROUND/AIM: The aim of the study was to evaluate histological liver lesions and to compare these with the results of biochemical parametres. METHODOLOGY: An experimental model of chronic ulcerative colitis in rats was utilized. RESULTS: Histological studies of the biliary tree showed progressive fibrotic inflammation which fulfilled the criteria of early sclerosing cholangitis. The biochemical tests of liver function were, however normal in all animals. CONCLUSIONS: Sclerosing cholangitis in experimental ulcerative colitis is a progressive disease, and normal liver biochemistry does not exclude changes in liver histology.

Animals↗