PubMed Health⌕ Search

Biomedical subjects

R Yalin

Publications and source records attributed to R Yalin.

At least 37 records · Page 2Linked to original sources
PubMed1993

A case of inappropriate non-neoplastic secretion of TSH treated with bromocriptine.

A 67 year old patient with overt signs of hyperthyroidism had high serum TSH values in addition to high T3 and T4 values. Initial treatment with propyltiouracil (PTU) reduced the high serum thyroid hormone levels but TSH levels were further increased. With an augmented TSH response to TRH and negative sella tomography, diagnosis of inappropriate secretion of TSH was made. PTU was stopped and bromocriptine 10 mg daily given with perfect result in 18 weeks. The patient is euthyroid on bromocriptine therapy.

Aged↗
PubMed1993

Importance of testing stapled rectal anastomoses with air.

OBJECTIVE: To compare the air test (insufflation of air through the anus after the peritoneal cavity has been filled with saline) and the completeness of doughnuts as indicators of the integrity of stapled rectal anastomoses. DESIGN: Prospective open study. SETTING: Marmara University Hospital, Istanbul, Turkey. SUBJECTS: 23 patients with sigmoid and rectal carcinoma. MAIN OUTCOME MEASURES: Correlation between positive air test, completeness of doughnuts, and clinical anastomotic breakdown. RESULTS: Two patients were withdrawn (one had a handsewn anastomosis and in one the air test was omitted). Five patients had positive air tests, and in four of these the doughnuts were complete. The leaks were repaired with additional sutures in three patients, and two were given covering colostomies. There was only one clinical anastomotic breakdown. CONCLUSION: The air test enabled the surgeon to repair or protect five anastomoses (24%). The completeness of the doughnuts was an reliable test of anastomotic integrity.

Adult↗
PubMed1992

Significance of intracystic pressure in abdominal hydatid disease.

A prospective study was performed in 32 patients (24 female, eight male) with 50 abdominal hydatid cysts, to assess whether intracystic pressure (ICP) could predict viability. The median ICP, measured during operation, was 35 cmH2O for 31 viable cysts and zero for nine non-viable cysts located in the liver (P < 0.05). The median ICP was significantly higher in cysts located in the left lobe of the liver than in those in the right (P < 0.05). The ICP was not significantly different in unilocular or multilocular cysts. ICP increased as the diameter of the cysts increased. The sensitivity of the indirect haemagglutination test was 86 per cent and the specificity 75 per cent. It is concluded that measurement of ICP is a simple and reliable method for assessment of the viability of abdominal hydatid cysts.

Adolescent↗
PubMed1992

The effect of iloprost and NDGA in ischemia reperfusion injury in rat liver.

In this study, the effects of iloprost (ZK 36374) and NDGA on warm ischemia and reperfusion injury in rat liver were investigated. Rats were given isotonic saline (control group), iloprost 25 micrograms/kg i.v. (group II) just before warm ischemia or NDGA 10 micrograms/kg i.v. (group III) 5 min before reperfusion or the same drugs were given together (group IV). Serum SGOT, SGPT, and LDH values and tissue malondialdehyde (MDA), glutathione (GSH), prostaglandin (PG)E2, and leukotriene (LT)C4 levels were determined after ischemia-reperfusion injury. Histopathologic examination of the liver was carried out under the light microscope. The serum SGOT, SGPT and LDH levels improved significantly in groups II, III, and IV when compared with the control group (p < 0.05). There was a significant decrease (p < 0.05) in tissue MDA levels and significant increase (p < 0.05) in tissue GSH levels in group I, when compared with group IV and the control groups. The values did not differ significantly in group IV when compared to controls. The LTC4/PGE2 ratio was low and histologic findings were worse in group III. In conclusion, iloprost was found to be beneficial in preventing the ischemia-reperfusion injury in the rat livers. NDGA, either by direct toxic effect or by shifting the arachidonic acid metabolism to the cyclooxygenase route, was not found to be as effective. Iloprost and NDGA did not exert a synergist effect.

Alanine Transaminase↗
PubMed1990

Preoperative prediction of postoperative complications.

The value of history taking, physical examination and routine laboratory tests as predictors of postoperative complications was investigated in 100 patients undergoing major surgery. Major and minor risk markers were identified and compared with major and minor postoperative complications. The results proved this approach to be a simple, inexpensive and reliable method for the prediction of postoperative complications.

Adolescent↗
PubMed1989

Median neuralgia caused by brachial pseudoaneurysm.

A rare neurovascular complication of a antebrachial arteriovenous fistula in a chronic hemodialysis patient is reported. A large brachial venous pseudoaneurysm caused median neuralgia by direct compression of the nerve. Surgical resection of the pseudoaneurysm resulted in complete relief of neuralgia.

Adolescent↗
PubMed1988

Treatment of experimental peritonitis with intraperitoneal povidone-iodine solution.

Intraperitoneal lavage with povidone-iodine solution has been reported by some to be beneficial in the treatment of peritonitis and by others to cause local and toxic side effects. In this study, 200 white mice, divided into four groups of 50, were subjected to bacterial peritonitis. The first group had no treatment; peritoneal lavage was carried out using povidone-iodine solution in the second group and a 0.9% sodium chloride solution in the third. In the fourth group, antibiotics (clindamycin and gentamicin) were instilled intraperitoneally without peritoneal lavage. The povidone-iodine solution had no beneficial effect, the death rate after 1 week (76%) being similar to that in the control group (78%) and much higher than that in mice treated with sodium chloride lavage (38%) and antibiotics without lavage (16%). A second series of experiments was, therefore, carried out to investigate the toxic effect of povidone-iodine solution intraperitoneally on mice without peritonitis; the solution was found to be toxic.

Animals↗
PubMed1980

Surgical treatment of hydatid disease of the liver.

The records of 100 consecutive cases of hydatid disease of the liver that were treated surgically were reviewed to determine the complications and the results of different surgical procedures applied. Of those, 74% had single cyst and in 70% the disease was confined to the right lobe of the liver. Marsupialization and omentoplasty were the most commonly used techniques, followed by cystectomy, tube drainage, and cystojejunostomy. Infection in the remaining cavity was the most common postoperative complication. The complication rates were higher in marsupialization and tube drainage when compared with omentoplasty and cystectomy. Omentoplasty and cystectomy led to a shorter hospitalization period. All of the patients who underwent omentoplasty or cystectomy had good results whereas only 28.1% of those on whom marsupialization was done and 27.3% of the patients who underwent tube drainage had good results. The overall mortality was 3%.

Adolescent↗
PubMed1979

Renal transplantation with multiple arteries.

Out of a total of 184 transplant operations there were 27 kidneys with 2 or more renal arteries. Five of these were in 23 related transplants. Ischaemic times were increased compared with those of kidneys with single arteries, but the incidence and duration of acute tubular necrosis and also the length of time spent in hospital were similar in both groups. Excessive bleeding and other complications were no more common than following single arterial anastomosis. Kidneys with multiple arteries can be used safely if careful interrupted suturing is performed, the kidneys are perfused before and kept cool during the procedure and polar arteries are not tied.

Humans↗
PubMedDate not supplied

Role of endothelins in trinitrobenzene sulfonic acid-induced colitis in rats.

To determine the role of endothelins (ET) on experimental colitis, following intracolonic trinitrobenzene sulfonic acid administration, rats were given orally either bosentan (BS), a nonselective ET receptor antagonist (100 mg/kg in 5% arabic gum), or arabic gum by gavage for 2 or 14 days. Macroscopic damage scores obtained in the vehicle (1.4+/-0.4), acute (4.8+/-0.6) and chronic (3.8+/-0.3) colitis groups were significantly higher than in the control group (0). BS treatment reduced the scores in both acute (3+/- 0.5) and chronic (2.3+/-0.5) colitis groups. Myeloperoxidase (MPO) activities of colonic tissues were elevated in acute and chronic colitis groups (325.1+/-44.9 and 431.8+/-54.6 U/g wet weight) as compared with the control group (73.6+/-11 U/g wet weight). Plasma protein oxidation levels were found to be significantly increased in the chronic colitis group (1,158.1+/-63.4 nmol/ml) compared with the control, ethanol and acute colitis groups (274.3+/-23.1, 490+/-52.2 and 422.2+/-50.5 nmol/ml). BS treatment significantly reduced both the protein oxidation level (375.5+/-46.9 nmol/ml) and MPO activity (167.5+/-35.8 U/g wet weight). The results of the present study suggest the involvement of ETs in the pathogenesis of colonic injury in this animal model of colitis.

Analysis of Variance↗
PubMedDate not supplied

The influence of hemodialysis on plasma fluoride.

Since storage of fluoride in the skeleton has been blamed as an etiologic factor in the development of renal osteodystrophy, we studied the influence of hemodialysis on plasma fluoride levels in 17 patients with chronic renal failure on regular hemodialysis. The fluoride level in dialysate was found to be 19 micrograms/L, and 7.2 +/- 1.2 micrograms/L in healthy persons. Before hemodialysis, the mean fluoride level was 117.3 +/- 8.4 micrograms/L. It decreased to 113.3 +/- 8.5 micrograms/L at the first hour of dialysis and to 105.7 +/- 8.6 micrograms/L at the end of the dialysis, with no significance. We suggest that it would be appropriate to use "very low-fluoride" dialysate in order to reduce the plasma fluoride levels in patients with chronic renal failure.

Adolescent↗