Biomedical subjects

R Zawadzki

Publications and source records attributed to R Zawadzki.

14 recordsLinked to original sources

PubMed2001

Results of total deafness treatment in young pre- and postlingually deafened children.

Developing a cochlear implant program is one of the most difficult problems we need to solve concerning young children. Application of cochlear implants to this group of patients gives hope for better speech and language development than using conventional hearing aids. Children comprise approximately 40% of all implanted patients at the Institute of Physiology and Pathology of Hearing in Warsaw. They are provided with different types of cochlear implants, 16 of which are included in the international comparative study EARS (Evaluation of Auditory Responses to Speech). In this paper results are presented of auditory speech perception in pre-, peri-and postlingual children using the multichannel cochlear implant systems COMBI 40 and 40+. All the children were regularly evaluated following the EARS procedure with a number of perception tests. Monitoring of auditory perception development is fundamental and allows prognosis of speech and language development in children.

Acoustic Stimulation↗

PubMed2000

First auditory brainstem implantation in Poland: auditory perception results over 12 months.

Auditory brainstem implants (ABIs) are a modern method of treatment of total bilateral deafness in cases of extracochlear origin. In most cases therapy is applied in patients with neurofibromatosis type 2 (NF2). This paper presents the results of surgical treatment and rehabilitation in a 28-year-old woman with bilateral, multiple tumours of the central nervous system causing total deafness. Simultaneous removal of the tumours and implantation of ABI allowed treatment of the potentially lethal pathology and hearing restoration. Improving auditory skills and excellent tests results were noted in the year following implantation.

Adult↗

PubMed1994

Effects of pediatric HIV infection and prenatal drug exposure on mental and psychomotor development.

Examined the effects of HIV infection and prenatal drug exposure on infant neurodevelopmental functioning. Three groups of infants were compared: HIV-infected infants, seroreverters, and a comparison group who were prenatally exposed to drugs, but not HIV. Two thirds of the HIV-infected and seroreverter infants were prenatally drug-exposed. Infants (ages 4-30 months) were administered the Bayley Scales of Infant Development. Children who were both HIV-infected and prenatally drug exposed performed significantly lower on both the mental and psychomotor scales of the Bayley. Drug exposure and neurological dysfunction were associated with mental development, whereas neurological dysfunction, drug exposure, and HIV status were associated with psychomotor development.

Child Development↗

PubMed1992

Cognitive assessment of human immunodeficiency virus-exposed children.

OBJECTIVE: To determine (1) the level of impairment in cognitive and motor functioning in human immunodeficiency virus (HIV)-exposed and HIV-infected preschool and school-age children; (2) cognitive strengths and weaknesses that characterize HIV-infected children; and (3) potential contributions of serostatus, neurologic impairment, and prenatal drug-exposure to cognitive functioning. DESIGN: Cross-sectional, single-blind study. SETTING: Pediatric neurology clinic at a large metropolitan hospital in New York, NY. PARTICIPANTS: Forty-one HIV-infected and eight seroreverter school-age children. INTERVENTIONS: The McCarthy Scales of Children's Abilities were administered to all children, as was the Neurologic Examination for Children. MEASUREMENTS/MAIN RESULTS: The obtained mean of the sample on the McCarthy Scales' General Cognitive Index was in the Borderline range, with 44% of the subjects scoring in the Mentally Retarded range. The most severe cognitive deficits were found on the Quantitative, Verbal, and Memory scales (Borderline range). Children infected with HIV with neurologic impairment performed significantly worse than did seroverters and neurologically normal HIV-infected children. There were no significant differences in cognitive functioning due to gender, ethnicity, and prenatal drug exposure. CONCLUSIONS: Cognitive deficits were detected in HIV-infected and seroreverted children. The presence of neurologic dysfunction in HIV-infected children markedly intensified these deficits.

Acquired Immunodeficiency Syndrome↗

PubMed1979