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Biomedical subjects

R Ziegenbein

Publications and source records attributed to R Ziegenbein.

At least 19 recordsLinked to original sources
PubMed2002

Medical savings accounts: a core feature of Singapore's health care system.

In 1984 Singapore adopted a system of Medisave accounts, individually owned accounts used to pay for many of the health care expenditures that in Germany would normally be covered by the obligatory or private health insurance. The fact that people are spending their own money rather than that of a third-party insurer has helped to curtail Singapore's health care costs, which were about 2.6% of gross domestic product in 1999 (Germany: 10.5%). Even with these low expenditures, the income of Singapore physicians is about the same in relation to average wages as physician income in Germany or the United States, and patients have easy access to such technology as computerised axial tomography, organ transplants and bypass surgery.

Journal Article↗
PubMed2000

[Laparoscopic single patient use instruments: expensive outsourcing of product quality?].

The supply of medical goods is an important critical success factor in German hospitals. One major managerial area in the procurement concerns the decision between single patient use (SPU) and multiple patient use (MPU) products. Especially laparoscopic instruments which are generally expensive are a field of interest for decision makers. Due to a lack of quantifiable factors describing the two different forms of supply alternatives with their effects on effectivity and efficiency of the procurement process and the final use are often not taken into account. Since it is expected that in the future more and more laparoscopic instruments will be needed there is a necessity for finding a concept allowing the identification of the "right" product. The Center for Hospital Management (CKM) has the aim to develop a corresponding approach but needs the help of the reader.

Data Collection↗
PubMed1999

[Interpersonal communication as a factor in successful development of a decision-oriented information systems model in the hospital].

The success of a decision-oriented hospital information system is primarily depending on the way of integration of the involved professionals in the development. The technical realisation of those systems is already supported by several tools. Interpersonal interactions on the other hand which take about 40 percent of the time of development are still methodically ignored. The medVista method promotes the active integration of all persons involved and supports the realisation of a technological model simultaneously. Substantial corrections usually arising after implementation are no longer necessary and the system will be accepted by users.

Decision Making, Organizational↗
PubMed1998

[Virtual workshop for hospital management].

Due to a survey of the CKM insufficient communication among different professional groups is one of the main causes for unused quality reserves and neglected potentials of efficiency in German hospitals. An essential reason for this insufficiency lies in the traditional concepts of education which are designed for the specialties of the different professional groups. With this these concepts only impart key qualifications such as social authority, ability for communication and ability for problem-solving in a small amount. The goal of the virtual workshop is to train students and trainees in communication and interdisciplinary problem-solving early by working together on a practical case in a Virtual Workshop team. On the other hand all relevant persons to talk to are involved in order to support a qualified preparation of decisions: employees of the project hospital, partners from industry and members of universities.

Education, Medical↗
PubMed1993

Anatomical examination of leg telangiectases with duplex scanning.

BACKGROUND: Earlier studies using Doppler ultrasound suggested that thigh telangiectasia might be associated with reflux in the larger subcutaneous veins. OBJECTIVE: The aim of the study was an accurate description of the anatomy of the venous drainage from thigh telangiectases and evaluation of the extent of venous valvular incompetence using a noninvasive imaging method. METHOD: High-definition color duplex ultrasonography was used to achieve the objective. RESULTS: Thirty-seven legs with lateral and/or medial thigh telangiectasia were examined. Patients studied were those without saphenofemoral, saphenopopliteal, or deep venous abnormalities on Doppler ultrasound examination. Altogether 53 sites were tested. In 89% reticular vein incompetence was found close to telangiectases. Often reticular vein incompetence was associated with reflux in larger epifascial veins. In 15% incompetent perforating veins were detected between reticular veins and the deep venous system. CONCLUSION: An accurate, functional reconstruction of the subcutaneous venous drainage was accomplished. It was found that telangiectasia was rarely an isolated condition, but was usually associated with incompetence in other elements in the venous drainage of the subcutaneous tissue.

Humans↗
PubMed1985

[Tumor marker diagnosis in non-seminomatous testicular tumors using human chorionic gonadotropin (HCG) and alpha fetoprotein (AFP)].

In 28 patients with non-seminomatous testicle tumour the tumour markers human chorionic gonadotropin (HCG) and alpha-fetoprotein (AFP) were determined radioimmunologically and enzymeimmunologically, respectively. While tumours with chorionic carcinoma (n = 8) always were marker-positive, in the embryonic carcinoma in 2 out of 10 cases falsely negative findings appeared. On 5 patients the biochemical monitoring of the course of the testicle tumour disease is demonstrated in detail by means of HCG and AFP and estimated as very helpful method. Advantages and problems of the marker diagnostics are shown and discussed. The positive marker findings were absolutely evident for a metastasation. On the other hand, marker negativation was not always to be equated with absence of a tumour and demanded a further control of the patient by means of all other available methods of diagnostics up to the second-look-operation.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1984

[Lymphocyte depletion after irradiation of the chest region dependent on irradiation technics].

In a prospective alternating study, the mediastinum of patients with bronchial carcinomas was preoperatively irradiated with 2000 cGy in ten fractions for an isodose of 80% by Co-60 stationary field or pendulum therapy. The leucocyte and lymphocyte blood count was determined every day. It was found out that the lymphocyte depression was significantly higher after pendulum therapy than after stationary field therapy. This is explained by the fact that the lymphocyte depression is caused rather by the irradiation of lymphocytes in the blood stream than by the irradiation of bone marrow.

Bronchial Neoplasms↗
PubMed1982

Enzymatic tests in the prognosis and course controls in bronchial carcinoma patients.

In 117 bronchial carcinoma patients hospitalized to receive radiation therapy, the serum levels of aldolase, LDH, alkaline phosphatase, GOT and GPT were checked prior to, during, and following radiation therapy at intervals of 4--6 weeks. Among the enzymes tested, aldolase proved to provide the best screening test for judging prognosis, course of disease and probable occurrence of recurrence or metastases.

Adenocarcinoma↗
PubMed1980

[The CEA-concentration in plasma of patients with colorectal carcinoma and polyps has been determined by radioimmunoassay (RIA, Z-gel-method)].

82% of the cancer patients and 52% of the patients with polyps showed CEA levels above the upper normal limit of 2,5 microgram/1. CEA-values of more than 10 microgram/1 could only be detected in patients with carcinoma. Complete removal of the tumour by surgery has been followed by a marked decrease of prior increased plasma-CEA to values in the normal range, which could not be observed in the cases with tumour residues or metastases. In the patient's follow-up recurrence or metastases could be recognized several months before clinical detection by a renewed increased of the CEA-level in plasma.

Carcinoembryonic Antigen↗
PubMed1979

Biological markers of human tumors and monitoring of cancer treatment.

The development of human tumors is accompanied very often by tumor-associated phenomena such as production of tumor-derived substances, production of certian substances in response to the tumor or immunological reactions. Up to now no of these phenomena can be used as a diagnostic cancer test but biological markers are increasingly used for monitoring progression and regression of human tumors. Basing on a number of own studies the value of the determination of CEA-serum level and urinary excretion of hydroxyprolin, spermidin and putrescin for monitoring the tumor behaviour particularly during cancer chemotherapy is demonstrated.

Alkaline Phosphatase↗