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Biomedical subjects

Ralf Th Krampe

Publications and source records attributed to Ralf Th Krampe.

5 recordsLinked to original sources

Adaptive task prioritization in aging: selective resource allocation to postural control is preserved in Alzheimer disease.

OBJECTIVE: With age, the performance of multiple tasks decreases, a pattern exaggerated in Alzheimer disease (AD). At the same time, recent research, based on adaptive theories of healthy aging, indicates a preference of older adults to allocate resources toward tasks of higher immediate value (e.g., postural control). This study investigated whether such models also hold for pathologic cognitive aging. METHOD: Using a dual-task paradigm, the authors combined a working memory with a postural control task under easy and difficult conditions in patients with AD, older adults, older adults low on performance on a cognitive marker test, and young adults (N = 40). Participants repeatedly performed a cognitive and a postural control task both simultaneously and in isolation over the course of eight sessions. RESULTS: Consistent with earlier studies on divided attention in age and AD, the authors found large dual-task performance decrements with age and more so in AD. When not challenged, patients with AD showed large performance decrements under dual-task conditions in both postural control and working memory. With increasing difficulty in the postural control task, however, older adults, and more so patients with AD, maintained a high level of functioning in postural control, as compared with working memory. CONCLUSION: The findings indicate that the theory of selective optimization with compensation extends to pathologic aging and have broad implications for models of dual-task performance and executive control in aging and AD.

Adult↗

Timing, sequencing, and executive control in repetitive movement production.

The authors demonstrate that the timing and sequencing of target durations require low-level timing and executive control. Sixteen young (M-sub(age) = 19 years) and 16 older (M-sub(age) = 70 years) adults participated in 2 experiments. In Experiment 1, individual mean-variance functions for low-level timing (isochronous tapping) and the sequencing of multiple targets (rhythm production) revealed (a) a dissociation of low-level timing and sequencing in both age groups, (b) negligible age differences for low-level timing, and (c) large age differences for sequencing. Experiment 2 supported the distinction between low-level timing and executive functions: Selection against a dominant rhythm and switching between rhythms impaired performances in both age groups and induced pronounced perseveration of the dominant pattern in older adults.

Adolescent↗

Synchronizing movements with the metronome: nonlinear error correction and unstable periodic orbits.

The control of human hand movements is investigated in a simple synchronization task. We propose and analyze a stochastic model based on nonlinear error correction; a mechanism which implies the existence of unstable periodic orbits. This prediction is tested in an experiment with human subjects. We find that our experimental data are in good agreement with numerical simulations of our theoretical model. These results suggest that feedback control of the human motor systems shows nonlinear behavior.

Hand↗

Aging, expertise and fine motor movement.

Age-graded decrements in accuracies and maximum speed of fine motor movements observed in numerous experimental studies have nurtured general factor explanations like the assumption of general age-related slowing of central cognitive processes. This review focuses on two domains of investigation that yielded challenges to general factor models. First, experimental approaches aiming at the decomposition of fine motor skills provide evidence for the dissociability of timing, sequencing, and executive control components that show differential rather than general age-related changes. Second, studies on cognitive-motor expertise demonstrate that age-related changes in critical skill components depend on individuals' time investments into specific practice activities. It is argued that the process dissociations observed at the behavioral level in developmental (i.e. age and expertise) studies reflect individuals' long-term adaptations to internal and external performance constraints. The outcomes of these adaptation processes are stable interindividual differences in component processes.

Adaptation, Physiological↗