Use of voriconazole in Scedosporium apiospermum keratitis.
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Aged↗
Biomedical subjects
Raman Malhotra
Publications and source records attributed to Raman Malhotra.
Bilateral dynamic proptosis due to frontoethmoidal sinus mucocele.
A 34-year-old man presented with bilateral inferior and lateral globe displacement and spontaneous, dynamic proptosis in both eyes, pulsatile in nature. Computed tomography and magnetic resonance imaging scans confirmed bilateral frontoethmoidal mucoceles with erosion of the orbital roof, and intracranial extension. Following a transcutaneous mini-trephine of the left orbital mucocele, the dynamic proptosis disappeared, and both proptosis and restriction of eye movements in the left eye improved. This is the first reported case of frontoethmoidal sinus mucocele causing bilateral spontaneous dynamic proptosis.
Adult↗
Thyroid orbitopathy.
BACKGROUND: Thyroid orbitopathy (thyroid eye disease, thyroid ophthalmopathy) is an organ specific, autoimmune disorder with the potential to cause severe functional and psychosocial effects. OBJECTIVE: This article reviews the clinical features with particular emphasis on current management. DISCUSSION: Thyroid orbitopathy is most prevalent in women aged 40-50 years and is usually associated with thyroid dysfunction. Clinical manifestations include soft tissue signs, lid retraction, lid lag, proptosis, restrictive myopathy, corneal exposure and optic neuropathy. Thyroid function tests are essential, while thyroid antibodies and imaging to demonstrate extraocular muscle enlargement may also aid diagnosis. Correction of thyroid dysfunction and supportive measures are necessary in all cases. Immunosuppression is reserved for moderate to severe active orbitopathy and rehabilitative surgery is generally used once the disease is quiescent. A good visual and cosmetic outcome requires close cooperation between the general practitioner, endocrinologist and ophthalmologist.
Female↗