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Ran Ginosar

Publications and source records attributed to Ran Ginosar.

3 recordsLinked to original sources

Algorithms and architectures for low power spike detection and alignment.

We introduce algorithms and architectures for automatic spike detection and alignment that are designed for low power. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel integral transform analysis and achieve 99% of the precision of a PCA detector, while requiring only 0.05% of the computational complexity. The algorithms execute autonomously, but require off-line training and setting of computational parameters. We employ pre-recorded neuronal signals to evaluate the accuracy of the proposed algorithms and architectures: the recorded data are processed by a standard PCA spike detection and alignment software algorithm, as well as by the several hardware algorithms, and the outcomes are compared.

Action Potentials↗

Analog frontend for multichannel neuronal recording system with spike and LFP separation.

A 0.35microm CMOS integrated circuit for multi-channel neuronal recording with twelve true-differential channels, band separation and digital offset calibration is presented. The measured signal is separated into a low-frequency local field potential and high-frequency spike data. Digitally programmable gains of up to 60 and 80 dB for the local field potential and spike bands are provided. DC offsets are compensated on both bands by means of digitally programmable DACs. Spike band is limited by a second order low-pass filter with digitally programmable cutoff frequency. The IC has been fabricated and tested. 3microV input referred noise on the spike data band was measured.

Action Potentials↗

Adaptive cardiac resynchronization therapy device: a simulation report.

We report the results of a simulation of an adaptive cardiac resynchronization therapy (CRT) device performing biventricular pacing in which the atrioventricular (AV) delay and interventricular (VV) interval parameters are changed dynamically in response to data provided by the simulated IEGMs and simulated hemodynamic sensors. A learning module, an artificial neural network, performs the adaptive part of the algorithm supervised by an algorithmic deterministic module, internally or externally from the implanted CRT or CRT-D. The simulated cardiac output obtained with the adaptive CRT device is considerably higher (30%) especially with higher heart rates than in the nonadaptive CRT mode and is likely to be translated into improvement in quality of life of patients with congestive heart failure.

Arrhythmias, Cardiac↗