Biomedical subjects
Publications and source records attributed to Randy A Bartels.
We demonstrate propagation of ultrafast laser pulses through a molecular gas acting as a transient wave plate under conditions of strong phase modulation. The resulting decomposition of a linearly polarized laser pulse into two nearly distinct, orthogonally polarized laser pulses is demonstrated with transiently aligned, linear molecules.
Two angiotensin II (Ang II)-specific receptors, AGTR1 and AGTR2, are expressed in the mammalian brain. Ang II actions on blood pressure regulation, water electrolyte balance, and hormone secretion are primarily mediated by AGTR1. The function of AGTR2 remains unclear. Here, we show that expression of the AGTR2 gene was absent in a female patient with mental retardation (MR) who had a balanced X;7 chromosomal translocation. Additionally, 8 of 590 unrelated male patients with MR were found to have sequence changes in the AGTR2 gene, including one frameshift and three missense mutations. These findings indicate a role for AGTR2 in brain development and cognitive function.