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Biomedical subjects

Remy R Coeytaux

Publications and source records attributed to Remy R Coeytaux.

9 recordsLinked to original sources
PubMed2006

Four methods of estimating the minimal important difference score were compared to establish a clinically significant change in Headache Impact Test.

OBJECTIVE: To estimate the smallest decrease in Headache Impact Test (HIT) scores that reflects meaningful clinical change among patients with chronic daily headache (CDH). STUDY DESIGN AND SETTING: We applied four methods of estimating the minimum important difference (MID) to data from 71 patients with CDH who participated in a clinical trial. The HIT was administered at baseline and at the 6-week follow-up assessment. Patients were considered to have experienced meaningful improvement if they reported that their headache condition was "somewhat better" or "much better" at the 6-week follow-up. RESULTS: Mean HIT scores at baseline and 6 weeks for all patients were 64.5 (standard deviation SD = 6.0) and 62.6 (SD = 5.7), respectively. HIT scores decreased 3.7 (SD = 4.4) and 1.4 (SD = 3.6) units, respectively, among patients who reported "somewhat better" change and those who reported no change at 6 weeks. Estimates of the MID of the HIT ranged from -2.7 to -2.3. CONCLUSIONS: The method that we judge to be most valid estimated the MID of the HIT at -2.3 units (95% confidence interval = -4.3, -0.3). This suggests that a between-group difference in HIT change scores of 2.3 units over time among patients with CDH reflects improvement in patients' headache condition that may be considered clinically significant.

Activities of Daily Living↗
PubMed2006

A randomized controlled trial of acupuncture for initiation of labor in nulliparous women.

OBJECTIVE: To evaluate the utility of outpatient acupuncture for labor stimulation. METHODS: Nulliparous women at 39 4/7 weeks or greater with a singleton gestation and Bishop score of less than 7 were randomized to usual medical care (control group) versus usual care and three outpatient acupuncture treatments (acupuncture group). Each treatment consisted of eight needles applied to bilateral points LI4, SP6, UB31, and UB32. The primary outcome was time elapsed from the time of randomization to delivery. Secondary outcomes included rates of cesarean section and induction of labor. Medical records were abstracted for maternal demographic, medical, and delivery outcome data. A priori sample size calculation revealed that 56 women were required to detect a 72-hour difference in delivery time with a power of 83% and an alpha of 0.05. Student's t-test, Chi-square, and Kaplan-Meier statistics were used to compare groups. RESULTS: Fifty-six women were randomized and completed the study procedures. Race, age, gestational age, and cervical Bishop score were similar in both groups. Mean time to delivery occurred 21 hours sooner in the acupuncture group, but this difference did not reach statistical significance (p = 0.36). Compared to controls, women in the acupuncture group tended to be more likely to labor spontaneously (70% vs. 50%, p = 0.12) and less likely to deliver by cesarean section (39% vs. 17%, p = 0.07). Of women who were not induced, those in the acupuncture group were more likely to be delivered than the controls at any point after enrollment (p = 0.05). CONCLUSION: Acupuncture is well tolerated among term nulliparous women and holds promise in reducing interventions that occur in post-term pregnancies.

Acupuncture Therapy↗
PubMed2006

Exploring outcomes associated with acupuncture.

OBJECTIVE: The objective was to explore various methods of assessing clinically meaningful change associated with a course of acupuncture treatments. DESIGN: The design was a prospective cohort study. SETTING: The setting was an acupuncture clinic staffed by two physician acupuncturists in a university-affiliated family practice center. SUBJECTS: Subjects consisted of consecutive new patients to an acupuncture clinic. OUTCOME MEASURES: Outcomes were measured using the Medical Outcomes Study Short-Form 36 (SF-36) and Measure Your Own Medical Outcomes Profile (MYMOP). Outcomes measured were global clinical change and patient satisfaction. RESULTS: Out of 112 eligible patients, 110 consented to the study and contributed baseline data. Of these, 80 (71%) completed the 2-month follow-up questionnaire. Mean age of study subjects was 54.5 (standard deviation, SD 17.6) years; 85 (77%) were female, and 75 (68%) were married. Mean number of acupuncture treatments during the 2-month follow-up period was 5.8 (SD, 3.5, range, 1 to 16). Statistically significant improvement from baseline to follow-up was observed with the bodily pain subscale of the SF-36 and with the MYMOP. Among those who completed the study, 52 (67%) felt that the main symptom for which they sought acupuncture had improved over the course of the study and 72 (90%) were satisfied with their treatment in the acupuncture clinic. CONCLUSIONS: The MYMOP instrument appears to be the most useful of the four measures used to evaluate clinical outcomes associated with a course of acupuncture treatments (SF-36, MYMOP, global clinical change, and patient satisfaction). This easy-to-administer instrument appears to be sensitive to clinical change over a 2-month period among patients who sought acupuncture for a wide variety of clinical conditions.

Acupuncture Therapy↗
PubMed2006

Variability in the diagnosis and point selection for persons with frequent headache by traditional Chinese medicine acupuncturists.

OBJECTIVES: The aim of this study was to compare Traditional Chinese Medicine (TCM) pattern diagnosis and acupuncture point selection for persons with frequent headache, as ascribed by three highly trained, licensed acupuncturists. METHODS: Thirty-seven (37) study participants with frequent headaches were independently evaluated by three licensed acupuncturists trained in TCM. The acupuncturists identified the meridians and type of dysfunction they believed were contributing to study participants' symptoms. Study acupuncturists also ascribed one or more TCM diagnoses to each participant and selected eight acupuncture points for needling. RESULTS: Some variation in TCM pattern diagnosis and point selection was observed for all subjects. Liver Yang and Qi dysfunction were diagnosed in more than two thirds of subjects. Acupuncture points Liver 3, Large Intestine 4, and Governing Vessel (DU) 20 were the most commonly selected points for treatment. CONCLUSIONS: Headache is a heterogeneous condition represented by a wide variety of TCM diagnoses. There is variability among acupuncturists in the diagnosis of TCM patterns and the selection of acupuncture points for needling. These data suggest, however, that most persons with frequent headache appear to have liver Yang and Qi disharmonies for which needling of Liver 3, Large Intestine 4, and/or Governing Vessel 20 may be appropriate. Further research is needed to determine the extent to which variability in the diagnosis or acupuncture point selection among acupuncturists affects clinical outcomes.

Acupuncture Points↗
PubMed2005

A randomized, controlled trial of acupuncture for chronic daily headache.

BACKGROUND: Approximately 4% of adults experience headaches nearly every day. Nonpharmacologic interventions for frequent headaches may be appropriate because medical management alone is often ineffective. OBJECTIVE: To assess the efficacy of acupuncture as an adjunct to medical management for chronic daily headache (CDH). METHODS: We conducted a randomized, controlled trial of 74 patients with CDH that compared medical management provided by neurologists to medical management plus 10 acupuncture treatments. Primary outcome measures were daily pain severity and headache-related quality of life (QoL). RESULTS: Patients who received only medical management did not demonstrate improvement in any of the standardized measures. Daily pain severity scores trended downward but did not differ between treatment groups (P= .60). Relative to medical management only, medical management plus acupuncture was associated with an improvement of 3.0 points (95% CI, 1.0 to 4.9) on the Headache Impact Test and an increase of 8 or more points on the role limitations due to physical problems, social functioning, and general mental health domains of the Short Form 36 Health Survey. Patients who received acupuncture were 3.7 times more likely (CI, 1.7 to 8.1) to report less suffering from headaches at 6 weeks (absolute risk reduction 46%; number needed to treat 2). CONCLUSION: Headache-specialty medical management alone was not associated with improved clinical outcomes among our study population. Supplementing medical management with acupuncture, however, resulted in improvements in health-related QoL and the perception by patients that they suffered less from headaches.

Acupuncture Therapy↗
PubMed2005

Psychometric properties of the HIT-6 among patients in a headache-specialty practice.

OBJECTIVE: To evaluate the performance and score interpretability of the Headache Impact Test (HIT-6) questionnaire in a headache patient population. BACKGROUND: The HIT-6 is a standardized questionnaire designed to assess headache-related disability. Norms have been established using randomly sampled respondents from the general population. This study evaluated the psychometric properties of the HIT-6 scale among new adult patients who presented for treatment at a university headache-specialty practice. METHODS: Participants were 309 new patients who presented for treatment at a headache-specialty clinic in an academic medical center. RESULTS: Respondents ranged in age from 18 to 91 years, with an average age of 41 years (SD = 13 years) and were predominantly female (77%). Over half (57%) experienced chronic daily headache. Scores ranged from 38 to 78, with an average of 65.6 (SD = 7.0) and the majority (87%) had "severe impact" (60 or higher). The scale showed high reliability (alpha= 0.87) and an exploratory factor analysis showed large loadings from |0.57| to |0.86| and suggested a single disability factor. Scores were moderately negatively correlated with Short Form Health Survey (SF-36) subscales, ranging from -0.22 for mental health to -0.57 for social functioning. Item response theory analyses showed that half of the items functioned well across the disability continuum, while the remaining items discriminated between low and high levels of headache impact. CONCLUSIONS: These findings suggest that the HIT-6 is useful for assessing headache-related disability among patients who seek headache-specialty care.

Adolescent↗
PubMed2002

Standard scales for measurement of functional outcome for cervical pain or dysfunction: a systematic review.

STUDY DESIGN: A systematic review was conducted. OBJECTIVE: To identify, evaluate, and compare standard scales for assessing neck pain or dysfunction. SUMMARY OF BACKGROUND DATA: The degree of a patient's neck pain or dysfunction can be evaluated using standardized scales at the time of a clinical encounter or during the performance of clinical research protocols. The choice of a scale with the most appropriate characteristics, however, is always a challenge to clinicians and researchers. METHODS: Articles concerning scales for functional evaluation of neck pain or dysfunction were identified by computer searching of MEDLINE (January 1966 to June 1999) and CINAHL (1985 to 2000), citation tracking using the Citation Index, hand searching of relevant journals, and correspondence with experts. RESULTS: Five standard scales were found. Three scales were remarkably similar in terms of structure and psychometric properties: the Neck Disability Index, the Copenhagen Neck Functional Disability Scale, and the Northwick Park Scale. However, only the first instrument has been revalidated in different study populations. The Neck Pain and Disability Scale provides a visual template for collection of information, but its usefulness is limited if the questionnaire must be read to the patient. The Patient-Specific Functional Scale is very sensitive to functional changes in individual patients, but comparisons between patients are virtually impossible. CONCLUSIONS: The five scales identified in this study have similar characteristics. The Neck Disability Index, however, has been revalidated more times for evaluation of patient groups. For individual patient follow-up evaluation, the Patient-Specific Functional Scale has high sensitivity to change, and thus represents a good choice for clinical use. The final choice should be tailored according to the target population and the purpose of the evaluation.

Disability Evaluation↗
PubMedDate not supplied

Racial disparities in health between white and African American family practice patients: clinical implications.

OBJECTIVE: To identify differences in self-reported health status and prevalence of chronic disease between African American and white patients. STUDY DESIGN: A representative sample of African American and white adult patients from a stratified sample of family practices in North Carolina completed a questionnaire that included self-reported racial status, certain sociodemographic data, health risk factors, chronic conditions, and health status measures. DATA SOURCE: The North Carolina Health Project, a practice-based cohort of adult patients from a representative sample of family practice offices in North Carolina. PRINCIPAL FINDINGS: African Americans report poorer general health status than whites. Obesity insufficient exercise, high blood pressure, and diabetes are more prevalent among African American than white family practice patients, even after adjusting for age, gender, and educational attainment. CONCLUSIONS: This study complements previous evidence of disparities in chronic disease and health risk factors between African Americans and whites, and it highlights specific factors that may be important in the primary care setting. RELEVANCE: By focusing clinical attention on the prevention or treatment of specific factors that are known to be more prevalent among certain racial groups, primary care providers may help to reduce racial differences in healthcare.

Black or African American↗