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Richard F Spaide

Publications and source records attributed to Richard F Spaide.

77 records · Page 5Linked to original sources
PubMedDate not supplied

Neovascular age-related macular degeneration: roundtable.

Several recent developments may provide an opportunity to improve outcome in individuals who develop neovascular age-related maculopathy (age-related macular degeneration [ARMD]). Concurrent with progress in isolating clinically relevant subtypes of neovascular ARMD, several therapies have been introduced that show promise for halting progression of this disorder. However, data from controlled clinical trials to test the relative efficacy of different management strategies across these subtypes of disease presentation remain limited. In addition, strategies to control ARMD may evolve quickly as more is learned about how specific molecular events, such as cell-mediated inflammation and angiogenesis, contribute to disease expression. A roundtable of investigators was convened to discuss and summarize recent progress in the treatment of ARMD. Case studies were then presented to provide an opportunity for experts to reveal their specific thought processes in the approach to neovascular ARMD based on their own interpretation of current clinical data and empirical experience.

Adult↗
PubMedDate not supplied

Syphilitic retinitis with focal inflammatory accumulations.

A 42-year-old man with a history of human immunodeficiency virus and previous immune reconstitution after initiating a highly active antiretroviral therapy regimen was referred to rule out cytomegalo-virus retinitis. He had an unusual juxtapapillary collection of white superficial material and multiple preretinal collections resting on a peripheral ground glass opacification of the retina. These lesions quickly resolved after initiating treatment for syphilitic retinitis. The patient appeared to have developed an exaggerated response to the ocular syphilitic infection that may be related to the augmentation of his impaired immune system by highly active antiretroviral therapy.

Adult↗