Biomedical subjects

Rita Sollien

Publications and source records attributed to Rita Sollien.

5 recordsLinked to original sources

PubMed2006

Longitudinal reference ranges for estimated fetal weight.

OBJECTIVE: The aims of the present study were to establish reference ranges for the growth of estimated fetal weight (EFW) between gestational weeks 20 and 42 and to determine the effect of fetal and maternal factors. METHODS: This prospective longitudinal study was based on 634 low-risk pregnancies and a total of 1799 examinations. Gestational age was computed from last menstrual period. Head circumference, abdominal circumference, and femur length were measured using ultrasound, and EFW was calculated using the formula of Combs et al. The statistical analysis was based on regression analysis and multilevel modeling. RESULTS: Intrauterine growth expressed by EFW showed a continuous pattern until term. Males were calculated to be 5% heavier than female fetuses at 20 gestational weeks and 3% at 40 weeks. Otherwise, the fetal and maternal effects on intrauterine growth correspond to a weight shift of 1.3% for breech/nonbreech, 2.5% for each increase in maternal height tertile, and -4% for smoking/nonsmoking. Maternal age higher than 34 years had a significant increased EFW of 4.5% compared with maternal age less than 24 years. Cephalic index in the third tertile had a 1.1% lower EFW compared with the first tertile. Maternal weight, body mass index, and parity did not influence the EFW. Terms for customization to individualize the growth patterns are presented. CONCLUSIONS: The present growth chart is recommended as robust reference ranges for assessing EFW and growth. Fetal and maternal variables can be added into the models to individualize the prediction of EFW.

Adult↗

PubMed2006

Accuracy of second trimester fetal head circumference and biparietal diameter for predicting the time of spontaneous birth.

AIMS: Previous studies suggested that head circumference (HC) predicts the date of confinement better than the biparietal diameter (BPD). The present study aimed to prospectively test this assumption. METHODS: A prospective study including 4179 consecutive women attending the second trimester routine ultrasound examination at 17-20 weeks of gestation. Outer-outer BPD and HC were determined as the average of three repeated measurements. Twins were excluded. Time of delivery was noted, the differences between this and the predicted date of delivery calculated with HC and BPD (based on a pregnancy duration of 282 days), and the two methods were compared using Wilcoxon signed rank test. RESULTS: For the entire group, the median differences between actual and predicted delivery with HC and BPD were 0.9 and 1.2 days, respectively. For deliveries with a spontaneous onset of labor (n=3336) the corresponding differences were 0.9 and 1.4 days. The difference between the HC and BPD methods was significant (P<0.0001). In the group of spontaneous onset of labor, there were 05.6% post-term pregnancies (>or=296 days) according to HC and 5.7% according to BPD. CONCLUSION: Provided that the expected pregnancy duration was 282 days, both HC and BPD predicted spontaneous birth with a mean accuracy of one day, HC being significantly better than BPD.

Anthropometry↗

PubMed2005

Longitudinal reference charts for growth of the fetal head, abdomen and femur.

OBJECTIVES: The aims of the present study were to establish improved reference charts for growth of the fetal head, abdomen and femur, and to determine the effect of fetal and maternal factors. STUDY DESIGN: This prospective longitudinal study included 650 low-risk pregnancies. Outer-outer biparietal diameter (BPD), head circumference (HC), mean abdominal diameter (MAD), abdominal circumference (AC) and femur length (FL) were measured by ultrasound, and the statistical analysis was based on regression analysis and multilevel modeling. RESULTS: Reference percentiles for the growth of MAD, AC and FL showed continuous growth in gestational week 10-40, while BPD and HC showed a slightly blunted growth toward the end of pregnancy. FL was the only variable that was not influenced by gender. There was a significant negative association between breech presentation and all five biometrical variables, while maternal weight was positively associated with all five variables. Cephalic index significantly influenced BPD and HC. Maternal height had a positive effect on BPD, HC, AC and FL, and parity had a positive effect on MAD and AC, while smoking influenced negatively HC, MAD, and FL. Terms for calculating conditional reference values and customisation for individualised growth assessment are presented. CONCLUSIONS: New reference charts for the growth of fetal head, abdomen and femur are suggested for assessing fetal size and growth, and can be adjusted for maternal and fetal factors to suite individual pregnancies.

Abdomen↗

PubMed2005

Fetal age assessment based on femur length at 10-25 weeks of gestation, and reference ranges for femur length to head circumference ratios.

BACKGROUND: The aim of the present study is to establish new reference charts for gestational age assessment based on fetal femur length (FL), and new reference ranges for FL to head ratios at gestational weeks 10-25, and to determine the effect of maternal and fetal factors on these charts. METHODS: Six hundred fifty low-risk women with regular menstrual periods and singleton pregnancies were recruited to a prospective cross-sectional study after obtaining written consent. FL, outer-outer biparietal diameter (BPD), and head circumference (HC) were measured at 10-25 weeks of gestation. We used regression analysis in order to construct mean curves and to assess the effect of maternal and fetal factors on age assessment. RESULTS: The new chart for age assessment by means of FL was based on 636 measurements. The 95% CI of the mean corresponded to <1 day. The variation between the mean and the 90th percentile was 5, 6, and 7 days at 13, 18, and 23 weeks, respectively, similar to the results when using BPD or HC. Maternal age modestly influenced gestational age assessment (1.3 days/10 years, P = 0.005), whereas smoking, height, body mass index, multiparity, fetal sex, cephalic index, and breech presentation had no impact. Reference charts for FL to head ratios have been presented. Maternal age, fetal sex, and cephalic index influenced the FL/BPD ratio, whereas only fetal sex influenced FL/HC. CONCLUSIONS: Fetal age assessment based on FL is an equally robust method as using HC. FL/HC is a more robust ratio to characterize fetal proportions than is FL/BPD.

Adolescent↗

PubMed2004

Fetal age assessment based on ultrasound head biometry and the effect of maternal and fetal factors.

BACKGROUND: Maternal height and weight have increased during the past 20 years, as has birthweight. The aim of the present study was to establish new reference charts for gestational age (GA) assessment using fetal biparietal diameter (BPD) and head circumference (HC), and to determine the effect of maternal and fetal factors on age assessment. METHODS: This was a prospective, cross-sectional study of 650 healthy women with regular menstrual periods and singleton uncomplicated pregnancies, recruited after written consent. BPD (outer-outer) and HC were measured at 10-24 weeks of gestation. We used regression analysis to construct mean curves and assess the effect of maternal and fetal factors on age assessment. RESULTS: BPD and HC were successfully measured in 642 participants. Using BPD and HC before 20 weeks, the new charts gave 3-8 days higher GA assessment than the charts presently in use, and <1 day difference compared to other recently established charts. Maternal age, multiparity, fetal gender, breech position and shape of fetal head affect GA estimation by 1-2 days when using BPD (p = 0.0001-0.02). Only maternal age and fetal gender affected GA estimation when using HC (</= 1 day, p = 0.001). CONCLUSIONS: Our new charts for assessing gestational age based on fetal head biometry are notably different from charts presently in use. Maternal and especially fetal factors affect gestational age assessment when using BPD, but less so for the HC method, which is suggested as the more robust method.

Adolescent↗