Depressive disorders.
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Antidepressive Agents↗
Biomedical subjects
Rob Butler
Publications and source records attributed to Rob Butler.
Meralgia paresthetica: an unusual complication of cardiac catheterization via the femoral artery.
Nerve complications following cardiac catheterization via the femoral route are rare. We report a case of meralgia paresthetica, a mononeuropathy affecting the lateral cutaneous nerve of the thigh following uncomplicated cardiac catheterization and percutaneous intervention via this route.
Angina, Unstable↗
Stent deployment with distal vascular protection for the culprit vein graft stenosis in a patient with an acute infarct and cardiogenic shock.
A case of emergency stent deployment to a critical vein graft lesion in a patient with an acute myocardial infarction and cardiogenic shock is described. An Angioguard vascular protection device was used, retrieving a large amount of atheromatous debris. Use of filter-type protection devices to prevent distal atheroembolism may be lifesaving in such patients.
Aged↗
What are older peoples' experiences of taking antidepressants?
BACKGROUND: Antidepressants are prescribed widely to older people but little is known about older peoples' own reported experiences of taking them in routine practice. METHODS: A doctor interviewed 92 people, aged over 65, with a hospital diagnosis of depression, who had been prescribed an antidepressant in the past year. RESULTS: Most of the subjects were prescribed a selective serotonin reuptake inhibitor (SSRI), at a standard dose, for at least 8 weeks. Most people felt the antidepressants were helpful, although a third felt they made no difference. Two thirds of older people reported having adverse effects of which most were moderate or severe. The most common adverse effects were headache and dry mouth. Only a third said that they always took their tablets. LIMITATIONS: The sample was restricted to older people seen by hospital services. Interviews were carried out by a doctor and patients may not have been entirely truthful. CONCLUSIONS: Older people have important views about their treatment that they are prepared to tell a doctor. A lot of older people do not think their antidepressants are helpful, and the majority experience adverse effects. Many do not always take their medication. Doctors should routinely ask older people about their experiences of taking antidepressants.
Age Factors↗
The T allele of the C(677)T 5,10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism may protect endothelial function in young, normal subjects.
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5,10-Methylenetetrahydrofolate Reductase (FADH2)↗