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Biomedical subjects

Robert Alan Goldberg

Publications and source records attributed to Robert Alan Goldberg.

14 recordsLinked to original sources

What causes eyelid bags? Analysis of 114 consecutive patients.

BACKGROUND: The purpose of this study was to identify the anatomical basis for perception of lower eyelid bags in patients seeking aesthetic surgery and to evaluate the cumulative contribution of different anatomic characteristics before surgery. METHODS: The histories and photographs of patients whose motivation for aesthetic consultation was lower eyelid bags were analyzed. Six categories of anatomic basis for the lower eyelid bags were identified. For each patient, a score from 0 to 4 was given in each category. The cumulative contribution score for each category was calculated as total points for that category for all patients, divided by the 456 total available points. The authors also developed a "uniqueness score" to reflect the percentage contribution of the worst identified anatomic problem compared with the other problems. This was calculated for each patient as the maximum score in one category, divided by total points for that patient. RESULTS: A total of 114 consecutive cases were evaluated (67 men and 47 women; mean age, 52 +/- 11 years; age range, 23 to 76 years). The cumulative contribution score for each anatomic variable was as follows: cheek descent and hollow tear trough, 52 percent; prolapse of orbital fat, 48; skin laxity and sun damage, 35; eyelid fluid, 32; orbicularis hyperactivity, 20; and triangular cheek festoon, 13. Prolapsed orbital fat and tear trough deformity both received the higher score and were more common in men as compared with women. The average uniqueness score was 38 percent, with a range of 20 to 75 percent. No one category played a dominant role for most patients. Tear trough depression, skin laxity, and triangular malar mound were significantly more common in patients older than 50 years. Linear regression analysis showed that recommendation for surgery is based on the extent of fat prolapse, skin elasticity, and midface descent. Significant positive correlations were found in all six categories and in uniqueness scores calculated by different observers (r values ranged from 0.31 to 0.73; p < 0.001, Pearson correlation), with the highest score in agreement with the contribution of eyelids fat (r = 0.73) and skin laxity (r = 0.66); the uniqueness score correlation was r = 0.45 (p < 0.001). CONCLUSIONS: Eyelid bags do not have a single anatomic basis. For different anatomic problems, different treatments are recommended.

Adipose Tissue↗

Elegant diagnosis.

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Diagnosis, Differential↗

Treatment of prominent eyes with orbital rim onlay implants: four-year experience.

PURPOSE: Different approaches have been proposed to address the aesthetic or reconstructive challenge associated with relatively prominent eyes. Operations that address the soft tissues alone are prone to failure if the underlying orbital bony relationships are not addressed. Orbital rim advancement can serve as a supplement to orbital decompression in this setting or as an alternative for patients who may not maximally benefit from decompression surgery. METHODS: We report our 4-year experience with porous polyethylene orbital rim onlay grafts used to address relative proptosis in 24 patients. RESULTS: All patients had some degree of subjective and objective improvement. Proptosis decreased an average of 4.65 mm, with a range of 3 to 9 mm, based on single-observer Hertel exophthalmometry measurements (5.2 mm in those with concomitant decompression). Lagophthalmos was also improved in all patients with preoperative inadequacy in eyelid closure. Interpalpebral fissure size was reduced 1.3 mm on average, with a range of 0.5 to 6 mm (2 mm in those with concomitant decompression). Average follow-up was 41 months, with a range of 7 to 70 months. In 3 cases, we noted postoperative lower eyelid retraction with eyelid adhesion to the implant; possible risk factors for this complication included reoperative cases and simultaneous eyelid reconstruction with hard palate grafts. CONCLUSIONS: The porous polyethylene orbital rim onlay implant offers a relatively simple and effective surgical technique for the treatment of symptomatic relative proptosis. It can be used alone or in combination with other techniques including midface lift, lower eyelid retractor recession, and orbital decompression. To be effective, the implant should be placed so that it is flush with or overlapping the orbital rim; lateral displacement negates the effect of the implant in improving the eyelid/globe relationship. Postoperative eyelid retraction with tethering to the implant is a potential risk of the onlay implant, and although it may not be possible to avoid this in all cases, surgeries should be designed to minimize postoperative eyelid retraction.

Anthropometry↗

Potential utility of radiofrequency-induced thermal lesions in the orbit.

PURPOSE: Although rare, primary orbital neoplasms are a cause of significant morbidity. For the most part, the proximity of orbital tumors to delicate ocular neural and microvascular structures renders their surgical excision challenging. We investigated the utility of radiofrequency-induced thermal lesions in a rabbit model as potential means of less invasive therapy for benign orbital tumors. METHODS: A small radiofrequency (RF) probe was inserted through the conjunctiva at the fornix and guided along the orbital rim toward the apex of rabbit orbits. The exact location of the probe was ascertained using magnetic resonance (MR) imaging before heating. RF currents at a frequency of 500,000 Hz were conveyed through the exposed tip of a thin RF probe, causing a steady tissue temperature of 90 degrees C for 120 seconds. RESULTS: By using this technology, we induced targeted, localized, and reproducible elliptical thermocoagulative lesions in the rabbit orbit. CONCLUSIONS: We believe this technology has promise as a less invasive alternative or adjunct to open surgical debulking of difficult orbital tumors.

Animals↗

The horizontal dynamic of the medial and lateral canthus.

PURPOSE: To identify and quantify the horizontal dynamic movement of the medial and lateral canthus in subjects without previous eyelid surgery. METHODS: Prospective, experimental study. RESULTS: Seventy-two eyes in 36 normal subjects were studied. Frontal view lateral canthal movement with abduction of the globe averaged -0.4 mm (negative numbers mean the canthus moves in the opposite direction of the globe), with a range of -3.8 to 2.1. Profile view lateral canthal movement with abduction of the globe averaged 1.6 mm, with a range of -2.2 to 4.7 mm. Frontal view lateral canthal movement with adduction of the globe averaged -0.3 mm, with a range of -3.7 to 3.9 mm. Profile view lateral canthal movement with adduction of the globe averaged 0.5 mm, with a range of -2.4 to 3.9 mm. Frontal view medial canthal movement with abduction of the globe averaged -0.4 mm, with a range of -3.9 to 1.5 mm. Frontal view medial canthal movement with adduction of the globe averaged 0.1 mm, with a range of -5.2 to 4.6 mm. Intrasubject variation was observed for all measurements. CONCLUSIONS: The medial canthus and the lateral canthus are dynamic structures that move with horizontal eye movements in patients who have not undergone canthoplasty. The measured movement of the lateral canthus differed, based on the position from which the measurements were made, and was not always in the direction of the globe. The movement of the lateral canthus and the medial canthus differed on the right and left sides of the same subject.

Adolescent↗

Bovine hydroxyapatite orbital implant: a preliminary report.

PURPOSE: To determine the safety and efficacy of bovine hydroxyapatite as an orbital implant material. METHODS: Prospective, consecutive case series of patients undergoing enucleation, evisceration, or secondary orbital implantation. A motility peg was placed in all consenting candidates. Patients were followed 1 week, 1 month, and several months after surgery for signs of inflammation, infection, extrusion, or other complication. RESULTS: Twenty-seven patients received a bovine hydroxyapatite orbital implant. Magnetic resonance imaging was obtained in 3 patients (3 orbits) approximately 4 weeks after surgery and showed signs of peripheral fibrovascular ingrowth in all three cases. Magnetic resonance imaging was obtained in 9 patients (9 orbits) 4 to 12 months after surgery and showed signs of incomplete fibrovascular ingrowth in 1 of 9 (11%) cases, subtotal fibrovascular ingrowth in 2 of 9 (22%) cases, and complete fibrovascular ingrowth in 6 of 9 (67%) of cases. Complications included postoperative chemosis in 3 cases (11%) and exposure requiring reoperation in 2 cases (7%). Motility peg placement was performed successfully in 5 patients (5 orbits). CONCLUSIONS: Bovine hydroxyapatite appears to be a safe and effective orbital implant material. The material appears to be biocompatible and nonallergenic. Bovine hydroxyapatite allows for fibrovascular integration and motility peg placement.

Adolescent↗

Orbital volume augmentation for late enophthalmos using the deep lateral wall.

Orbital volume augmentation to address enophthalmos and hollowing of the superior sulcus has been described with a variety of materials and from a variety of approaches.(1-4) A common location for volume augmentation is the inferomedial orbital wall; this surface is often the one that was expanded related to orbital trauma, and it is easily accessed through hidden conjunctival or caruncular incisions.

Adult↗

Filling the periorbital hollows with hyaluronic acid gel: initial experience with 244 injections.

PURPOSE: To review our initial experience using hyaluronic acid gel (Restylane) as a filler to treat the periorbital hollows. METHODS: This is a retrospective, anecdotal case review of 244 cosmetic hyaluronic acid gel injections in 155 patients. An average volume of 0.9 ml per injection session was used in an individualized pattern that variably included the orbital rim hollow, zygomatic hollow, septal confluence hollow, and eyebrow and cheek fat pad. To achieve smooth contours, a layered, feathered threading technique was used, placing the filler deep to the orbicularis. Hyaluronidase injections were used in 11% of patients at follow-up visits to "dissolve" some of the filler to reduce contour irregularities. RESULTS: One hundred eight of 121 (89%) patients with follow-up visits were satisfied with the cosmetic improvement after hyaluronic acid gel injections. For maintenance, the interval to second injection averaged 6.5 months. Side effects included lumps or contour irregularities (11%), bruising (10%), color change (7%), and fluid (15%). Twelve patients were unsatisfied and were not interested in additional injections: 5 with malar fluid, 3 with lumpy irregularity, and 3 with color change. CONCLUSIONS: Complex 3-dimensional contours and thin skin over bone render periorbital filling difficult. However, with individualized planning and with care taken to create smooth, feathered contours, it is possible to achieve acceptable improvement. We found that most patients considered themselves improved cosmetically, despite occasional side effects including contour irregularity or lumps, bruising, color change, and fluid accumulation. Patients with very thin skin, preexisting color problems, or preexisting eyelid fluid may not be good candidates for periorbital filling with hyaluronic acid gel. The effect of the filler is temporary, of course, and we counsel patients to anticipate maintenance injections at 6- to 12-month intervals.

Adult↗