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Biomedical subjects

Robert J Cabay

Publications and source records attributed to Robert J Cabay.

6 recordsLinked to original sources

Fine-needle aspiration biopsy of a case of breast carcinoma with choriocarcinomatous features.

Breast disease is of great concern to patients and health care providers alike. Malignancies of the breast and their various presentations can pose tremendous challenges with respect to early diagnosis and effective treatment. Carcinoma of the breast may appear in several forms and produce one or more ectopic substances. Breast carcinomas that display choriocarcinomatous differentiation and produce human chorionic gonadotropin are very rare. Less than a dozen such cases have been described in the medical literature to date. We report a case of breast carcinoma with choriocarcinomatous features, which is the first to show immunohistochemical evidence of the expression of both estrogen receptor and progesterone receptor. We also discuss the cytopathologic aspects observed and conduct a literature review.

Biopsy, Fine-Needle↗

Paratesticular papillary mesothelioma: a case with borderline features.

Most often, mesotheliomas involve the serosal (serous) membranes of the pleura and peritoneum. Sometimes, mesothelial proliferations are identified in other locations. On very rare occasions, a mesothelioma is found within the tunica vaginalis of the paratesticular region. We report a case of papillary mesothelioma of the tunica vaginalis in a 52-year-old man. Although this lesion had papillary structures lined by a single layer of mesothelial cells with predominantly bland nuclear and cytologic features, there was evidence of a minimal presence of mesothelial cells in the underlying stroma. This combination of benign and semimalignant characteristics can make the diagnosis of such a lesion problematic. We think that a diagnosis of "borderline papillary mesothelioma" can be considered for similar mesothelial proliferations to allow for a possible increase in diagnostic accuracy and provide an enhanced informational platform from which patients and clinicians can benefit.

Biomarkers, Tumor↗

Oral malignancies in HIV disease: changes in disease presentation, increasing understanding of molecular pathogenesis, and current management.

Infection with human immunodeficiency virus (HIV) and progression to acquired immune deficiency syndrome (AIDS) are associated with a vide variety of morbidities. Local and systemic diseases can develop in association with HIV infection and may manifest themselves as malignancies of the oropharynx. Advances in HIV management, fueled by increasing understanding of molecular pathogenesis, have resulted in marked changes in the prevalence of oral malignant disease. This paper discusses recent trends in the presentation and treatment of malignancies related to HIV and AIDS with an emphasis on malignancies seen in the oral cavity.

Animals↗

Diabetes mellitus: an updated overview of medical management and dental implications.

Diabetes mellitus (DM) is a major worldwide public health concern. In the United States, 18.2 million people (approximately 6.3% of the population) currently suffer from DM; of those, nearly one-third are undiagnosed. The incidence of DM in the U.S. is expected to double by the year 2010 due to general aging among the population and the epidemic of obesity in the western world. Dental providers must be aware of the rapid changes concerning management of individuals with DM and must understand the significant impact DM has on dental treatment.

Blood Glucose↗