Unexpected gift keeps on giving.
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Biomedical subjects
Publications and source records attributed to Robert J Goldman.
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OBJECTIVE: To retrospectively evaluate the ability of high voltage pulsed current (HVPC) to increase microcirculation in critically ischemic wounds (transcutaneous oxygen [TcPO(2)] less than 10 mm Hg) and, as a result, to improve wound healing. DESIGN AND METHODS: Clinical case series with successive adult diabetic subjects (3 men and 3 women) with nonsurgical ischemic malleolar or inframalleolar skin lesions, each subject serving as his or her own control. Wound area and TcPO(2) were measured periodically. Presence of distal arteriosclerosis was assessed on 5 patients by 2-dimensional, time-of-flight magnetic resonance angiography. End point was either complete wound closure or leg amputation. RESULTS: Maximum mean TcPO(2) was 2 +/- 2 mm Hg at the wound edge before the start of electrotherapy. After electrotherapy began, maximum TcPO(2) was 33 +/- 18 mm Hg (N=6; P<.05, Wilcoxon signed rank test). After treatment with HVPC, 4 patients' wounds healed and 2 patients underwent amputation. As expected, healed patients initially deteriorated after the start of treatment, but their wounds began healing when the perilesion TcPO(2) measurement exceeded 20 mm Hg. Thereafter, the wounds closed at a predictable rate. Complete closure occurred for patients who had a relatively low atherosclerotic burden. CONCLUSION: The results of this clinical case series suggest that electrotherapy can improve periwound microcirculation of ischemic inframalleolar skin lesions.
PURPOSE: To improve clinical practice and the quality of patient care by providing a learning opportunity that enhances the participant's understanding of the tools and techniques available for wound measurement. TARGET AUDIENCE: This CME/CE activity is intended for physicians and nurses with an interest in learning about tools and techniques available for wound measurement. OBJECTIVES: After reading the article and taking the test, the participant will be able to: Identify advantages and disadvantages of various dimensional methods used to measure wounds. Identify advantages and disadvantages of visual and photographic assessment methods. Identify advantages and disadvantages of vascular and pressure assessment methods.
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This case study describes a pivotal intervention associated with improved wound appearance and healing rate in a young, active woman with extensive venous stasis ulcers. These extensive ulcerations were heavily exudative and covered by a layer of yellow eschar. Yellow eschar and drainage were successfully managed with a capillary dressing (Vacutex), which promoted therapeutic compression as applied by standard dressings. This case provides data in favour of wound care protocols featuring Vacutex, specifically designed to address the consequences that wound drainage and eschar have in dramatically large venous stasis ulcers.
Our long-term goal is to improve adherence to a home-based isometric program for rehabilitation of knee osteoarthritis (OA) using a force-biofeedback device (Isopad). Our goal for Phase I was to design and evaluate an Isopad-based program in a supervised clinical setting. Our subjects were five patients with knee OA of Kellgren stage II or greater. A capacitive force sensor was tested for accuracy, repeatability, and durability. An Arthritis Foundation home-based isometric program inspired the Isopad design. The Isopad provided visual and auditory feedback instantaneously and continuously about force generated between the ankles. The five subjects completed a supervised 8-week progressive isometric program using the Isopad. Absolute isolated quadriceps and hamstring torques were quantified with a dynamometer, and patients completed a self-assessment of symptoms (Western Ontario and McMaster Universities Osteoarthritis Index). The capacitive sensor accuracy error averaged 10% and repeatability 4%. Cognitively intact subjects used the Isopad successfully for isometric progressive resistance training. Quadriceps and hamstrings absolute torques increased an average of 30%. Patients reported decreased functional complaints (Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index). All changes were trends. The Isopad helped subjects with knee OA adhere to a supervised isometric program and meet progressive strength targets. The next-generation Isopad will be employed in a home-based program.
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