Biomedical subjects

Robert Shannon

Publications and source records attributed to Robert Shannon.

2 recordsLinked to original sources

PubMed2007

The first successful case of hearing produced by electrical stimulation of the human midbrain.

HYPOTHESIS: Electrical stimulation of the inferior colliculus in the midbrain can provide a safe and efficacious alternative to auditory brainstem implants (ABIs). BACKGROUND: Patients with neurofibromatosis type 2 (NF2) receive limited speech recognition with ABIs. Some ABI patients without NF2 can achieve excellent speech understanding, suggesting that the limited NF2 performance is due to brainstem damage from the tumor and its removal. METHODS: An array of electrodes (Med-El ABI) was placed on the dorsal surface of the inferior colliculus in the midbrain of a human volunteer as an auditory prosthesis via an infratentorial supracerebellar median surgical approach. Electrophysiological responses, psychophysical responses, and speech recognition were measured. RESULTS: Electrical stimulation produced auditory sensations on all 12 electrodes with no nonauditory sensations. Auditory threshold levels indicated the stability of the electrode array over time. Electrophysiological measures showed activation in the contralateral auditory cortex but none in ipsilateral cortex. All electrodes demonstrated a full range of loudness sensation and electrode-specific pitch sensations. Speech recognition was significant, but limited in the first month after surgery. CONCLUSION: This approach may provide advantages for patients with brainstem damage.

Adult↗

PubMed2002

Speech dynamic range and its effect on cochlear implant performance.

This study examines optimal conversions of speech sounds to audible electric currents in cochlear-implant listeners. The speech dynamic range was measured for 20 consonants and 12 vowels spoken by five female and five male talkers. Even when the maximal root-mean-square (rms) level was normalized for all phoneme tokens, both broadband and narrow-band acoustic analyses showed an approximately 50-dB distribution of speech envelope levels. Phoneme recognition was also obtained in ten CLARION implant users as a function of the input dynamic range from 10 to 80 dB in 10-dB steps. Acoustic amplitudes within a specified input dynamic range were logarithmically mapped into the 10-20-dB range of electric stimulation typically found in cochlear-implant users. Consistent with acoustic data, the perceptual data showed that a 50-60-dB input dynamic range produced optimal speech recognition in these implant users. The present results indicate that speech dynamic range is much greater than the commonly assumed 30-dB range. A new amplitude mapping strategy, based on envelope distribution differences between consonants and vowels, is proposed to optimize acoustic-to-electric mapping of speech sounds. This new strategy will use a logarithmic map for low-frequency channels and a more compressive map for high-frequency channels, and may improve overall speech recognition for cochlear-implant users.

Adult↗