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Biomedical subjects

Robert Thayer Sataloff

Publications and source records attributed to Robert Thayer Sataloff.

12 recordsLinked to original sources
PubMed2004

Dysphonia due to Kaposi's sarcoma as the presenting symptom of human immunodeficiency virus.

Dysphonia and airway obstruction are rarely caused by Kaposi's Sarcoma (KS). We present the case of a 40 year old man receiving his diagnosis of human immunodeficiency virus (HIV) after presenting with hoarseness caused by laryngeal KS. HIV may contribute to KS growth by stimulating excess production of angiogenic lymphokines and monokines and by decreasing immune surveillance. Histopathology reveals proliferating endothelial cells, fibroblasts, thin vascular slits, and extravasated erythrocytes. A wide variety of localized treatment options exist, while chemotherapeutic agents and alpha-interferon are used for multifocal or widespread disease.

Acquired Immunodeficiency Syndrome↗
PubMed2003

Phylogeny and embryology of the facial nerve and related structures. Part I: Phylogeny.

The study of evolution provides invaluable insights into human structure and function. Much of evolution is recapitulated during human gestation. Understanding the evolutionary process helps clarify seemingly complex embryology and anatomy, such as that of the facial nerve and related ear structures, as well as the anomalies that occur when human development is interrupted.

Anatomy, Comparative↗
PubMed2003

Phylogeny and embryology of the facial nerve and related structures. Part II: Embryology.

A precise description of the developmental anatomy of the facial nerve and associated ear structures, augmented by an appreciation of phylogenic history, has proven extremely helpful intraoperatively. Predictions of facial nerve position can be made with reasonable accuracy when they are based on a proper analysis of developmental anomalies of other ear structures. In cases in which the facial nerve canal has not developed, it may be impossible to obtain accurate localization of the facial nerve radiographically prior to surgery. In such cases, judgment based on an understanding of embryology may be the surgeon's only guide to the position of the facial nerve. Although these principles have proven valid and reliable so far, it is not prudent for the surgeon to consider them gospel, of course. Extreme caution must always be exercised when operating on an ear with congenitally abnormal anatomy. Nevertheless, it is not necessary for the surgeon to approach a congenitally malformed ear with the fear that "You never know where the facial nerve is going to be." Understanding embryology allows otologic surgery to be planned with reasonable accuracy and carried out safely and expeditiously.

Ear↗
PubMed2002

Strobovideolaryngoscopic findings in singing teachers.

Professional voice users often present to otolaryngologists and laryngologists with specific voice complaints. The contributions of pathologic lesions to the patients' vocal complaints are not always clear on examination, and often, premorbid examinations of the larynx are not available for review. This study examines the incidence of laryngeal pathology among singing teachers. At a national convention of singing teachers, volunteers were recruited for a "free strobovideolaryngoscopic examination." All volunteers completed a detailed questionnaire of their vocal and medical history and underwent strobovideolaryngoscopic examination. Strobovideolaryngoscopic examinations were completed in 20 volunteers, 7 of whom had voice complaints and 13 of whom perceived their voices to be normal. Vocal fold masses were common among the asymptomatic singing teachers. Evidence of reflux laryngitis was a common finding among both symptomatic and asymptomatic singing teachers. Asymmetries in vocal fold hypomobility were more common among those with voice complaints than was the presence of vocal fold masses in the population studied.

Adult↗
PubMed2002

Vocal tremor reduction with deep brain stimulation: a preliminary report.

Vocal tremor has been a challenging problem for patients and their physicians. In some cases, it has been possible to lesson the symptom's tremor through medications and/or voice therapy. However, in most cases no good treatment has been available. Chronic stimulation of the thalamus has been successful in controlling tremors of the upper limb and other portions of the body. Our preliminary experience suggests that it may also be helpful in controlling vocal tremor.

Aged↗
PubMed2002

A pilot survey of vocal health in young singers.

The objective of this study was to determine the incidence of vocal problems in young choir singers and to correlate vocal problems with demographic and behavioral information. A questionnaire addressing vocal habits and hygiene was offered to 571 young choir singers, up to 25 years of age, who sing at least weekly; 129 (22.6%) responded. More than one-half of the respondents had experienced vocal difficulty, particularly older adolescents. Detrimental behaviors and circumstances surveyed were not reflective of the incidence of vocal difficulty, except for morning hoarseness, chronic fatigue, insomnia, and female gender after puberty. Voice care professionals should be aware that self-reported voice difficulties are common among young choral singers, especially postpubescent girls, and children with symptoms consistent with reflux (morning hoarseness) and emotional stress (insomnia). Laryngologists should communicate with choral conductors and singing teachers to enhance early identification and treatment of children with voice complaints, and to develop choral educational strategies that help decrease their incidence.

Adolescent↗
PubMed2002

Laryngeal sarcoidosis.

Sarcoidosis is a chronic granulomatous disease that tends to involve the lungs, hilar and mediastinal lymph nodes, liver, eyes, skin, bones, and nervous system. Sarcoidosis involves the larynx less commonly than it afflicts these other sites. Laryngeal sarcoidosis may occur in isolation or as a component of systemic sarcoidosis and it may produce hoarseness, dysphagia, and dyspnea. Life-threatening airway obstruction can occur. Treatments used for laryngeal sarcoidosis have included tracheotomy, low-dose radiation, surgical excision, systemic steroids, and intralesional steroids. An autoimmune etiology has been suggested. The patient reported in this manuscript showed marked, sustained improvement following the use of inhaled steroids prescribed for obstructive pulmonary disease. The possible efficacy of steroid inhalers for treatment of laryngeal sarcoidosis warrants further investigation.

Administration, Inhalation↗
PubMed2002

Botulinum toxin type B for treatment of spasmodic dysphonia: a case report.

Although treatment with botulinum toxin type A (BTXA) has become the standard of care for most patients with laryngeal dystonia, its use is limited by the development of resistance to the toxin in some patients. Botulinum toxin type B (BTXB) has been found to be safe and effective in the treatment of cervical dystonia, but it has not been used previously to treat spasmodic dysphonia. Our experience with BTXB in a patient who developed resistance to BTXA suggests that BTXB may be safe and effective for the treatment of laryngeal dystonia, as well.

Botulinum Toxins↗
PubMed2002

Prolonged ulcerative laryngitis.

Acute and prolonged laryngitis commonly are diagnosed and treated by primary care physicians. These ailments come to the attention of the otolaryngologist when symptoms are prolonged despite treatment. Since the beginning of 1991, the senior authors (RTS, JRS) have recognized a clinical syndrome defined by prolonged hoarseness, prolonged laryngeal inflammation, and vocal fold ulceration. Patients are frequently young, nonsmokers, and nondrinkers who have had an upper respiratory infection prior to, or associated with, the onset of laryngeal symptomatology. Patients may be affected for up to 1 year despite aggressive medical therapy. This review of 14 patients highlights the features of this previously undescribed entity.

Adult↗
PubMed2002

Chondrosarcoma of the skull base.

OBJECTIVES: Sarcomas of the skull base are challenging, potentially lethal tumors. Prognosis is considered poor. The present report reviews treatment options and presents a case of treatment with en bloc resection of the temporal bone and adjacent skull base. STUDY DESIGN: Single case report and literature review. RESULTS: Extensive skull base resection for chondrosarcoma can be performed successfully and may be curative. CONCLUSION: There is a role for en bloc resection of large areas of the skull base for treatment of chondrosarcoma. It appears that treatment combining surgery and radiation therapy is most likely to be effective.

Adult↗