Robi Polikar | PubMed Health

PubMed2006

Comparative multiresolution wavelet analysis of ERP spectral bands using an ensemble of classifiers approach for early diagnosis of Alzheimer's disease.

Early diagnosis of Alzheimer's disease (AD) is becoming an increasingly important healthcare concern. Prior approaches analyzing event-related potentials (ERPs) had varying degrees of success, primarily due to smaller study cohorts, and the inherent difficulty of the problem. A new effort using multiresolution analysis of ERPs is described. Distinctions of this study include analyzing a larger cohort, comparing different wavelets and different frequency bands, using ensemble-based decisions and, most importantly, aiming the earliest possible diagnosis of the disease. Surprising yet promising outcomes indicate that ERPs in response to novel sounds of oddball paradigm may be more reliable as a biomarker than the more commonly used responses to target sounds.

Aged↗

PubMed2004

An incremental learning algorithm with confidence estimation for automated identification of NDE signals.

An incremental learning algorithm is introduced for learning new information from additional data that may later become available, after a classifier has already been trained using a previously available database. The proposed algorithm is capable of incrementally learning new information without forgetting previously acquired knowledge and without requiring access to the original database, even when new data include examples of previously unseen classes. Scenarios requiring such a learning algorithm are encountered often in nondestructive evaluation (NDE) in which large volumes of data are collected in batches over a period of time, and new defect types may become available in subsequent databases. The algorithm, named Learn++, takes advantage of synergistic generalization performance of an ensemble of classifiers in which each classifier is trained with a strategically chosen subset of the training databases that subsequently become available. The ensemble of classifiers then is combined through a weighted majority voting procedure. Learn++ is independent of the specific classifier(s) comprising the ensemble, and hence may be used with any supervised learning algorithm. The voting procedure also allows Learn++ to estimate the confidence in its own decision. We present the algorithm and its promising results on two separate ultrasonic weld inspection applications.

Journal Article↗