Biomedical subjects

Robin Gemmill

Publications and source records attributed to Robin Gemmill.

3 recordsLinked to original sources

PubMed2006

Cutaneous T-cell lymphoma.

OBJECTIVE: To review recent information on the epidemiology, etiology, clinical presentation, staging, treatment approaches, and nursing management of CTCL. DATA SOURCES: Research and review articles and textbooks. CONCLUSION: Identifying the etiology and finding a cure for cutaneous T-cell lymphoma is promising as our knowledge and understanding of the T-cell biology evolves, creating more options for innovative therapies or treatment modalities. IMPLICATIONS FOR NURSING PRACTICE: It is essential for the oncology nurse to understand the disease process, treatment modalities, and side effect profiles to provide astute nursing assessment, establishment of treatment goals, management of cutaneous symptoms, treatment of side effects, and pain control while preventing infection and providing psychological/social support throughout the course of the disease.

Antineoplastic Agents↗

PubMed2004

"Research to practice": a practical program to enhance the use of evidence-based practice at the unit level.

PURPOSE/OBJECTIVES: To assist clinical nurses in translating research into clinical practice. DATA SOURCES: City of Hope Quality-of-Life (QOL) Model to guide presentations and discussion, research utilization theories, and evidence-based practice literature. DATA SYNTHESIS: Based on percentage of individual participant involvement, the four domains of QOL, and a knowledge survey. OUTCOMES: Attendance, discussion, QOL domain ranking, satisfaction, and pre- and postknowledge scores. Attendance averaged 13 individuals; average discussion participation was 54%. The psychological QOL domain was most important (58%), and discussion averaged a score of 3 (1 = slow to 5 = lively). A one-point increase (scale 1-5) measured a change in knowledge. CONCLUSIONS: The challenge for nursing assessment is to fully address patient issues in the psychological domain. IMPLICATIONS FOR NURSING: A practical program can be formulated to bring evidence-based practice to the clinical setting.

Adult↗

PubMed2003

Biological advances for new treatment approaches.

OBJECTIVES: To review malignant cell characteristics, which serve as the basis for the development of molecular, targeted cancer therapies. To provide an introduction and overview of new targeted agents, including monoclonal antibodies, enzyme inhibitors, antiangiogenic agents, gene therapy, and vaccines. DATA SOURCES: Published scientific papers, review articles, and book chapters. CONCLUSION: Through new understandings and theories of how cancer cells survive, thrive, and metastasize, researchers have created new targeted therapies for cancer treatment to minimize the harmful systemic effects of traditional therapy. IMPLICATIONS FOR NURSING PRACTICE: As with any new therapeutic modality, scientific rationale and mechanism of action must be appreciated by health care staff to build a solid foundation for patient education and to provide astute management of acute and latent effects.

Angiogenesis Inhibitors↗