Biomedical subjects

Robin M Masheb

Publications and source records attributed to Robin M Masheb.

At least 19 recordsLinked to original sources

PubMed2007

Physical activity and its correlates in treatment-seeking obese patients with binge eating disorder.

OBJECTIVE: This study examined the physical activity levels reported by obese individuals with binge eating disorder (BED), as well as the relationships between physical activity and body mass index (BMI), features of eating disorders, and associated psychological variables. METHOD: A series of 166 obese treatment-seeking adults (121 women and 45 men) with BED were administered structured diagnostic interviews and self-report questionnaires. RESULTS: This clinical group was found to be extremely sedentary. Self-reported physical activity levels, measured by the Paffenbarger Physical Activity Questionnaire, were comparable with those reported by obese samples with or without binge eating in other studies, but were considerably lower than those reported by a community sample. Lifestyle physical activity (e.g., amounts of walking and stair climbing) and sports and recreational physical activity were unrelated to most clinical characteristics. BMI was significantly, albeit weakly, associated with reported sports and recreational activities in women, but not in men. CONCLUSION: Our findings highlight the degree to which obese patients with BED are inactive. Physical activity was largely uncorrelated with measures of eating disorder and psychological functioning in both men and women but was significantly, but weakly, correlated with BMI in women. Additional research is needed to determine the clinical value of physical activity for this patient group.

Adult↗

PubMed2006

Emotional overeating and its associations with eating disorder psychopathology among overweight patients with binge eating disorder.

OBJECTIVE: The current study examined emotional overeating in overweight patients with binge eating disorder (BED). A new measure--the Emotional Overeating Questionnaire (EOQ)--was developed to measure the frequency of overeating in response to emotions. The internal consistency, test-retest reliability, and factor structure of this measure were examined, and its associations with eating disorder psychopathology, depression, and gender were explored. METHOD: Two hundred twenty consecutive overweight (body mass index [BMI] > or = 25) treatment-seeking BED patients (48 men and 172 women) were administered the EOQ, which assesses overeating frequency in response to six emotions (anxiety, sadness, loneliness, tiredness, anger, and happiness). A subset of patients (n = 83) completed the measure again approximately 1 week later. BMI was measured, and participants completed measures of eating disorder psychopathology. RESULTS: The EOQ was internally consistent (alpha =.85), its items were significantly and moderately correlated (range .32 to .70) with each other, and principal components analysis revealed one factor accounting for 58% of the variance. The EOQ items and total score were characterized by good test-retest reliability (intraclass correlation coefficients [ICCs] ranged from .62 to .73). Significant correlations were found between the emotional overeating items and total score, and binge frequency, eating disorder features, and depressive symptomatology. Emotional overeating was unrelated to BMI, and men and women reported similar rates of emotional overeating. CONCLUSION: Emotional overeating was significantly associated with binge frequency, eating disorder features, and depression, but was not related to BMI or gender.

Adult↗

PubMed2006

Evaluating oneself by shape and weight is not the same as being dissatisfied about shape and weight: A longitudinal examination in severely obese gastric bypass patients.

OBJECTIVE: This study examined two related and confused body image constructs--overevaluation and body image dissatisfaction--and tested their distinctiveness by examining their longitudinal associations with changes in self-esteem and negative affect. METHOD: One hundred forty-five obese (mean BMI = 51.6, SD = 7.5) patients (16 men and 129 women) completed a battery of self-report measures prior to and six months after undergoing gastric bypass surgery. Measures of body image (overevaluation of shape and weight, and body image dissatisfaction), self-esteem, and negative affect were assessed. RESULTS: Overevaluation and body image dissatisfaction both improved substantially following surgery. Change in overevaluation was significantly correlated only with change in self-esteem (after controlling for negative affect). Whereas change in body image dissatisfaction was significantly correlated with changes in both self-esteem and negative affect; findings for partial correlations remained unchanged. CONCLUSION: These findings demonstrate that evaluating oneself by shape and weight is related to, but not the same as, being dissatisfied about shape and weight. Given that overevaluation is less likely to be influenced by mood, it appears to be a more stable marker for disturbance in body image than body image dissatisfaction. This distinction has important implications for how clinicians and researchers assess these constructs.

Adult↗

PubMed2006

Personal standards and evaluative concerns dimensions of "clinical" perfectionism: a reply to Shafran et al. (2002, 2003) and Hewitt et al. (2003).

Shafran, Cooper, and Fairburn (2002, 2003) provided a cognitive-behavioral analysis of "clinical" perfectionism, a construct they considered to involve both the determined pursuit of self-imposed standards and extremely vulnerable self-evaluation. They argued against a multidimensional perspective to studying perfectionism. We respond to Shafran et al. (2002, 2003) and Hewitt, Flett, Besser, Sherry, and McGee's (2003) reply to Shafran et al. (2002) by considering the theoretical, empirical, and clinical implications of findings identifying two higher-order dimensions of perfectionism reflecting personal standards (PS) and self-critical evaluative concerns. Analyses of data from two diverse study groups, a college student sample (N = 527) and a clinical sample of patients with binge eating disorder (N = 236), revealed that self-criticism accounts for the relation between perfectionism measures and depressive, anxious, and eating disorder symptoms. We conclude that possessing high PS is not by itself maladaptive. Rather, self-critical evaluative tendencies are more relevant than PS to the critical processes Shafran et al. (2002) suggested contribute to the maintenance of clinical perfectionism.

Adult↗

PubMed2006

Reliability of the Eating Disorder Examination-Questionnaire in patients with binge eating disorder.

This study examined the test-retest reliability of the Eating Disorder Examination-Questionnaire (EDE-Q) in patients with binge eating disorder (BED). Short-term (mean days = 4.8; SD = 3.6) test-retest reliability of the EDE was examined in a sample of 86 patients with BED. Test-retest reliability was excellent for objective bulimic episodes (correlation = .84), but poor to unacceptable for subjective bulimic episodes and objective overeating episodes (correlations = .51 and .39, respectively). Test-retest reliabilities were good for the EDE-Q scales (correlations = .66 to .77), albeit somewhat variable for the individual EDE-Q items (.54 to .78). These findings support the reliability of the EDE-Q for patients with BED. The EDE-Q has utility for assessing the number of binge eating episodes (objective bulimic episodes) and associated features of eating disorders in patients with BED. The results for subjective bulimic episodes are consistent with previous studies in suggesting that these eating behaviors may not be reliable indicators of eating disorders for patients with BED.

Adult↗

PubMed2006

Rapid response to treatment for binge eating disorder.

The authors examined rapid response among 108 patients with binge eating disorder (BED) who were randomly assigned to 1 of 4 16-week treatments: fluoxetine, placebo, cognitive-behavioral therapy (CBT) plus fluoxetine, or CBT plus placebo. Rapid response, defined as 65% or greater reduction in binge eating by the 4th treatment week, was determined by receiver operating characteristic curves. Rapid response characterized 44% of participants and was unrelated to participants' demographic or baseline characteristics. Participants with rapid response were more likely to achieve binge-eating remission, had greater improvements in eating-disorder psychopathology, and had greater weight loss than participants without rapid response. Rapid response had different prognostic significance and distinct time courses for CBT versus pharmacotherapy-only treatments. Rapid response has utility for predicting outcomes and provides evidence for specificity of treatment effects with BED.

Adolescent↗

PubMed2006

Relation of childhood sexual abuse and other forms of maltreatment to 12-month postoperative outcomes in extremely obese gastric bypass patients.

BACKGROUND: The prognostic significance of sexual abuse for extremely obese patients who undergo bariatric surgery is uncertain. This study examined self-reported childhood sexual abuse and other forms of childhood maltreatment in relation to preoperative presentation and to 12-month postoperative outcomes in gastric bypass patients. METHODS: 137 extremely obese patients undergoing gastric bypass surgery completed a questionnaire battery before surgery and again 12 months after surgery. Weight loss was determined with measured weight and height, childhood maltreatment was assessed with the Childhood Trauma Questionnaire, and associated eating disorder and psychological functioning were assessed with established measures. RESULTS: 32% of patients self-reported childhood sexual abuse, 37% reported some form of non-sexual childhood abuse or neglect, and 31% reported no form of childhood maltreatment. Significant and clinically robust improvements in weight and in all measures of eating and psychological functioning were observed at 12 months after surgery. Patients who reported histories of childhood sexual abuse and other forms of childhood maltreatment differed little from patients who reported no childhood maltreatment in body mass index, eating disorder features, and psychological functioning both pre- and postoperatively at 12-month follow-up. Patients who reported childhood sexual abuse had statistically significantly higher levels of depression at 12 months after surgery, although the depression levels represented significant reductions from pre-surgery and fell within the non-depressed range. CONCLUSION: Extremely obese patients who seek gastric bypass surgery report higher rates of childhood maltreatment than normative community samples. A history of childhood maltreatment, including reports of sexual abuse, does not appear to be a negative prognostic indicator for gastric bypass surgery.

Adult↗

PubMed2006

A prospective study of body dissatisfaction and concerns in extremely obese gastric bypass patients: 6- and 12-month postoperative outcomes.

BACKGROUND: Body image is a multifaceted construct commonly associated with obesity. This study examined changes in body dissatisfaction, and shape and weight concerns in bariatric surgery patients from baseline to 6 and 12 months post-surgery. METHODS: 109 extremely obese patients who underwent gastric bypass surgery completed the Body Shape Questionnaire (BSQ), and the Shape and Weight Concern subscales of the Eating Disorder Examination-Questionnaire (EDE-Q) at baseline, and 6 and 12 months post-surgery. RESULTS: Patients experienced substantial weight loss and reported statistically significant reductions in BSQ, and Shape and Weight Concern scores from baseline to 6 and 12 months post-surgery. Improvements on the BSQ and Shape Concern scale were maintained between 6 and 12 months post-surgery, while patients reported continued reductions in weight and Weight Concern scale scores. Moreover, at 6 and 12 months follow-up, over 80% of female patients had body image scores comparable to published norms. Correlations between change in BMI and the body image measures were variable, and degree of weight loss did not predict body image scores 6 or 12 months post-surgery. CONCLUSIONS: Results from the present study illustrate significant and immediate post-surgical reductions in body dissatisfaction and concerns, along with weight loss in bariatric patients. Such improvements indicate a normalization of body image-related concerns in these patients, the majority of who remain overweight or obese despite the substantial post-surgical weight losses. Changes in weight and body image relate poorly to each other, suggesting that mediating factors may be involved.

Adolescent↗

PubMed2006

The prognostic significance of regular binge eating in extremely obese gastric bypass patients: 12-month postoperative outcomes.

OBJECTIVE: The prognostic significance of binge eating for extremely obese patients who undergo bariatric surgery is uncertain. We examined the relation of preoperative binge eating to preoperative presentation and 12-month postoperative outcomes. METHODS: 139 extremely obese gastric bypass surgery patients completed assessments of binge eating and eating disorders (Eating Disorder Examination-Questionnaire version), body dissatisfaction (Body Shape Questionnaire), depression (Beck Depression Inventory), and self-esteem (Rosenberg Self-Esteem Scale) before surgery and again 12 months postsurgery. RESULTS: At baseline, 60% of patients denied binge eating, 16% reported binge eating infrequently (less than once weekly), and 24% reported binge eating at least weekly. At 12 months postsurgery, 8.8% reported infrequent binge eating and only 0.7% reported binge eating weekly. At baseline, infrequent binge eaters and regular binge eaters differed little from each other but had significantly elevated eating and psychosocial problems relative to non-binge eaters. Statistically significant and clinically robust improvements in weight and in all measures of functioning were observed at 12 months postsurgery across all groups. At 12-month follow-up, patients who reported regular binge eating at baseline had significantly higher levels of eating-specific concerns (but not psychosocial concerns) than the infrequent binge eaters and non-binge eaters; the infrequent and non-binge eaters did not differ from each other. Significant time-by-binge eating interactions indicated that the regular versus infrequent binge-eating groups improved differently over time; infrequent binge eaters had sharper improvements than regular binge eaters and non-binge eaters. CONCLUSION: Binge eating is common in extremely obese bariatric surgery candidates and is associated with heightened eating and psychological problems. Regular binge eating preoperatively, however, does not appear to be a potent negative prognostic indicator for gastric bypass surgery. Our findings, which are limited to 12 months postsurgery, highlight substantial improvements in weight and psychosocial functioning, and these robust improvements differ little by binge-eating status.

Adult↗

PubMed2006

Vulvodynia: a state-of-the-art consensus on definitions, diagnosis and management.

Vulvodynia is a chronic pain syndrome affecting up to 18% of the female population. Despite its high prevalence and associated distress, the etiology, diagnosis and clinical management of the disorder have not been clearly delineated. This "white paper" describes the findings and recommendations of a consensus conference panel based on a comprehensive review of the published literature on vulvodynia in addition to expert presentations on research findings and clinical management approaches. The consensus panel also identified key topics and issues forfurther research, including the role of inflammatory mechanisms and genetic factors and psychosexual contributors.

Biomedical Research↗

PubMed2005

Eating patterns and breakfast consumption in obese patients with binge eating disorder.

This study examined eating patterns and breakfast consumption, and their relationships to weight and binge eating, in obese individuals with binge eating disorder (BED). One-hundred seventy-three consecutively evaluated men (n=46) and women (n=127) with BED were administered semi-structured interviews and self-report measures to assess the frequency of meals and snacks eaten, as well as binge eating and eating disorder features. Overall, those who consumed more frequent meals, particularly breakfast, and snacks, weighed less. Breakfast, which was eaten on a daily basis by less than half of participants (n=74; 43%), was the least frequently eaten meal of the day. Participants (n=56; 32%) who ate three meals per day weighed significantly less, and had significantly fewer binges, than participants (n=117; 68%) who did not regularly eat three meals per day. Thus, eating more frequently, having breakfast and consuming three meals every day, have potentially important clinical applications for the treatment of BED given that the effectiveness of specific interventions within treatments for BED are unknown, and that weight loss outcome for BED has been poor.

Adolescent↗

PubMed2005

Comparison of two self-report instruments for assessing binge eating in bariatric surgery candidates.

This study compared two self-report methods for assessing binge eating in severely obese bariatric surgery candidates. Participants were 249 gastric bypass candidates who completed the Questionnaire on Eating and Weight Patterns-Revised (QEWP-R) and the Eating Disorder Examination-Questionnaire (EDE-Q) prior to surgery. Participants were classified by binge eating status (i.e., no or recurrent binge eating) with each of the measures. The degree of agreement was examined, as well as the relationship between binge eating and measures of convergent validity. The two measures identified a similar number of patients with recurrent binge eating (i.e., at least 1 binge/week); however, overlap was modest (kappa=.26). Agreement on twice weekly binge eating was poor (kappa=.05). The QEWP-R and EDE-Q both identified clinically meaningful groups of binge eaters. The EDE-Q appeared to differentiate between non/infrequent bingers and recurrent bingers better than the QEWP-R, based on measures of convergent validity. In addition, the EDE-Q demonstrated an advantage because it identified binge eaters with elevated weight and shape overconcern. Using the self-report measures concurrently did not improve identification of binge eating in this study. More work is needed to determine the construct validity and clinical utility of these measures with gastric bypass patients.

Adult↗

PubMed2005

Cognitive behavioral therapy guided self-help and orlistat for the treatment of binge eating disorder: a randomized, double-blind, placebo-controlled trial.

BACKGROUND: Cognitive behavioral therapy (CBT) has efficacy for binge eating disorder (BED) but not obesity. No controlled studies have tested whether adding obesity medication to CBT facilitates weight loss. We performed a randomized, placebo-controlled study of orlistat administered with guided self-help CBT (CBTgsh). METHODS: Fifty obese BED patients were randomly assigned to 12-week treatments of either orlistat plus CBTgsh (120 mg three times a day [t.i.d.]) or placebo plus CBTgsh and were followed in double-blind fashion for 3 months after treatment. RESULTS: Seventy-eight percent of patients completed treatments without differential dropout between orlistat+CBTgsh and placebo+CBTgsh. Intent-to-treat remission rates (zero binges for past 28 days on Eating Disorder Examination Interview) were significantly higher for orlistat+CBTgsh than placebo+CBTgsh (64% versus 36%) at posttreatment but not at 3-month follow-up (52% in both). Intent-to-treat rates for achieving 5% weight loss were significantly higher for orlistat+CBTgsh than placebo+CBTgsh at posttreatment (36% versus 8%) and 3-month follow-up (32% versus 8%). Significant and comparable improvements in eating disorder psychopathology and psychological distress occurred in both treatments. CONCLUSIONS: The addition of orlistat to CBTgsh was associated with greater weight loss than the addition of placebo to CBTgsh. Clinical improvements were generally maintained at 3-month follow-up after treatment discontinuation.

Adult↗

PubMed2005

Efficacy of cognitive behavioral therapy and fluoxetine for the treatment of binge eating disorder: a randomized double-blind placebo-controlled comparison.

BACKGROUND: Cognitive behavioral therapy (CBT) and certain medications have been shown to be effective for binge eating disorder (BED), but no controlled studies have compared psychological and pharmacological therapies. We conducted a randomized, placebo-controlled study to test the efficacy of CBT and fluoxetine alone and in combination for BED. METHODS: 108 patients were randomized to one of four 16-week individual treatments: fluoxetine (60 mg/day), placebo, CBT plus fluoxetine (60 mg/day) or CBT plus placebo. Medications were provided in double-blind fashion. RESULTS: Of the 108 patients, 86 (80%) completed treatments. Remission rates (zero binges for 28 days) for completers were: 29% (fluoxetine), 30% (placebo), 55% (CBT+fluoxetine), and 73% (CBT+placebo). Intent-to-treat (ITT) remission rates were: 22% (fluoxetine), 26% (placebo), 50% (CBT+fluoxetine), and 61% (CBT+placebo). Completer and ITT analyses on remission and dimensional measures of binge eating, cognitive features, and psychological distress produced consistent findings. Fluoxetine was not superior to placebo, CBT+fluoxetine and CBT+placebo did not differ, and both CBT conditions were superior to fluoxetine and to placebo. Weight loss was modest, did not differ across treatments, but was associated with binge eating remission. CONCLUSIONS: CBT, but not fluoxetine, demonstrated efficacy for the behavioral and psychological features of BED, but not obesity.

Adult↗

PubMed2005

Body checking and avoidance in overweight patients with binge eating disorder.

OBJECTIVE: Repetitive body checking and avoidance are viewed as behavioral manifestations of the core psychopathology of eating disorders (EDs). We examined select body checking and avoidance behaviors in overweight patients with binge eating disorder (BED). METHOD: Three hundred seventy-seven overweight (body mass index [BMI] > or = 25) treatment-seeking BED patients (80 men and 297 women) were administered measures to assess body checking and avoidance, other key behavioral features of EDs (binge eating, dietary restraint, and disinhibition), and the core psychopathology of EDs (overevaluation of weight and shape). RESULTS: The majority of participants reported regularly pinching areas of their body to check for fatness and avoided wearing clothing that made them particularly aware of their body. Significant associations emerged between checking and restraint, and conversely, between avoidance and binge eating. Both checking and avoidance were positively and significantly associated with overevaluation of weight and shape, even after controlling for their unique effects. DISCUSSION: These findings offer support to the potential role of checking and avoidance behaviors in the maintenance of BED.

Adult↗

PubMed2005

Binge eating and self-esteem predict body image dissatisfaction among obese men and women seeking bariatric surgery.

OBJECTIVE: We examined body image dissatisfaction (BID) in extremely obese men and women seeking bariatric surgery. METHODS: The following predictors of BID were examined in a consecutive series of 260 (44 men and 216 women) gastric bypass candidates: gender, ethnicity, body mass index (BMI), age at onset of overweight, childhood maltreatment, binge eating, depression, and self-esteem. RESULTS: Women reported significantly higher levels of BID than men. Stepwise multiple regression analyses revealed that gender, binge eating, and self-esteem levels accounted for 41% of the variance in BID. In predicting BID levels separately by gender, binge eating and self-esteem accounted for 56% of the variance among men and for 33% of the variance among women. DISCUSSION: Among bariatric surgery candidates, women reported significantly higher BID than men. Our findings suggest the importance of binge eating and lower self-esteem for understanding BID in both men and women who are extremely obese.

Adult↗

PubMed2005

Treatment preferences of patients with binge eating disorder.

OBJECTIVE: The current study examined the treatment preferences of obese patients with binge eating disorder (BED). METHOD: Participants were 103 consecutive patients with BED who responded to advertisements for treatment studies looking for persons who wanted to "stop binge eating and lose weight." In addition to completing comprehensive assessment batteries, participants were provided descriptions of cognitive-behavioral therapy (CBT) and behavioral weight loss therapy (BWL) after which they were asked to choose and rate their preferred treatment. RESULTS: Sixty-three percent of participants stated they preferred CBT. Treatment preferences were not associated with (1) histories of obesity, dieting, binge eating, or weight cycling, (2) current obesity or eating disorder features, or (3) psychological features such as depression or self-esteem levels. In contrast, participants' stated treatment preferences were aligned with their perception of their primary problem (eating disorder vs. obesity) and their primary goals for treatment (stop binge eating vs. lose weight). The patients who preferred CBT based their treatment selection more on their problem perception than on their primary treatment goal, whereas the patients who preferred BWL selected treatment based more on their primary treatment goal (weight loss) than on their problem perception. DISCUSSION: Obese patients with BED express treatment preferences that are not associated with variability in their clinical characteristics but are aligned with their perception of their primary problem and with their primary goals for treatment.

Adult↗

PubMed2005

Correlates of body image dissatisfaction in treatment-seeking men and women with binge eating disorder.

OBJECTIVE: We examined body image dissatisfaction (BID) in patients with binge eating disorder (BED). METHOD: Six predictors were considered in 343 consecutive treatment-seeking BED patients (76 men, 267 women): body mass index (BMI), age onset of overweight childhood teasing about weight or size childhood teasing about general appearance, depression, and self-esteem. RESULTS: Women reported higher BID than men. In women, depression, self-esteem, and childhood teasing about weight or size jointly accounted for 28.4% of the variance in BID. In men, depression, self-esteem, and BMI jointly accounted for 47.4% of the variance in BID. DISCUSSION: Findings highlight gender differences and the importance of adult psychological functioning (depression and self-esteem) for predicting BID in treatment-seeking men and women with BED.

Adult↗