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Rolf Lindemann

Publications and source records attributed to Rolf Lindemann.

9 recordsLinked to original sources
PubMed2006

Alcohol use before and during pregnancy: a population-based study.

BACKGROUND: Few population-based studies have estimated alcohol consumption and binge drinking before and during pregnancy. METHODS: The study is a longitudinal questionnaire study. In Norway, virtually 100% attend an ultrasound screening at 17-18 weeks of pregnancy. In Oslo, a representative sample attending this between June 2000 and May 2001 were invited to join the study, accepted by 92%. Non-Norwegian-speaking and/or immigrants from non-Western countries were not invited; 1,749 (93%) completed the first questionnaire. MEASURES: T-ACE (screening for pregnancy risk drinking), frequency of alcohol use, Standard Units (SU) per occasion, SU/week, and binge drinking (>or=5 SU per occasion). Binary logistic regression analyses, Student's t-test and Pearson's chi square were used. RESULTS: Alcohol use was reported by 89% pre-pregnancy and by 23% after pregnancy week 12. Binge drinking was reported by 59% pre-pregnancy and by 25% during weeks 0-6. Change of drinking pattern occurred at pregnancy recognition for 85%, although 78% had planned the pregnancy, fetal welfare being the main reason. Participants reporting alcohol use during pregnancy were older, smokers, with more SU/week pre-pregnancy, had some elevated anxiety score, higher income, and a partner with higher education. However, mental health, high income, or education were not predictive of usually drinking 1 SU per occasion or more, and not of binge drinking. The latter was predicted mainly by smoking during pregnancy and being T-ACE positive. CONCLUSIONS: The study shows a drinking pattern before pregnancy recognition that, according to other studies, in 25% or more may cause suboptimal fetal development.

Adolescent↗
PubMed2006

Alcohol consumption, smoking and breastfeeding in the first six months after delivery.

AIM: To study alcohol use and smoking after delivery, and to relate this to breastfeeding. METHODS: A longitudinal questionnaire study, representative of pregnant women in Oslo. Ninety-two per cent agreed to join the study. Non-Norwegian speaking and/or immigrants from non-western countries were not invited. Questionnaires were answered at 17 (T1) and 30 (T2) wk of pregnancy, and 6 mo after term (T3). They were completed by 93% (1749 women) at T1, 82% at T2, and 92% at T3. RESULTS: Six months after delivery, 80% reported alcohol use. The mean alcohol consumption per week was less than half compared to the last 6 mo before pregnancy. The women with the highest pre-pregnancy use reduced the most. Binge drinking (> or = 5 drinks) was also reported by half as many women (29%). However, 6% reported 12 or more drinks per occasion at least once. No demographic or mental health variables predicted binge drinking after pregnancy. Smoking 6 mo after pregnancy was reported by 18%, a reduction of 50% from before pregnancy. Women breastfeeding for at least 6 mo had higher education, less frequently reported binge drinking after delivery and less frequently suffered postnatal depression. CONCLUSION: In this population-based sample were 86% breastfed for at least 6 mo, the level of binge drinking is concerning.

Adult↗
PubMed2006

Alcohol consumption before and during pregnancy comparing concurrent and retrospective reports.

BACKGROUND: Reported alcohol consumption during pregnancy has proven to be higher when reported retrospectively during or after the pregnancy, compared with concurrent reports. In a longitudinal, population-based questionnaire study, we investigated whether these findings could be replicated. METHODS: A longitudinal, population-based questionnaire study. Among a representative half of pregnant women in Oslo, 92% accepted to join the study. Non-Norwegian speaking and/or immigrants from nonwestern countries were not invited. Questionnaires were answered at 17 (T1) and 30 weeks of pregnancy (T2) and 6 months after term (T3). The response rate was at T1 93% (N = 1,749), at T2 82%, and at T3 94% [representing 86% (T1), 70% (T2), and 64% of those invited to join the study]. RESULTS: Significantly more alcohol consumption after pregnancy recognition was reported retrospectively at both T2 and T3 [T2 0.15 and T3 0.18 standard units per week (SU/wk)] than concurrently at T1 or T2 (T1 0.10 and T2 0.14 SU/wk). When comparing the 2 retrospective reports at T2 and T3, there was a significant increase over time. Predictive factors for higher retrospective reports were higher age, more SU per week before pregnancy, reported alcohol use after pregnancy recognition (at T1), and depression after the pregnancy. A predictive factor for lower retrospective reporting was anxiety during, but not after, the pregnancy. Contrary to previous suggestions, anxiety concerning abnormality in the 6-month-old child was not a predictive factor. CONCLUSION: Concurrently reported alcohol consumption during pregnancy is probably under-reported. Thus, concurrent reports appear to underestimate fetal exposure.

Adult↗
PubMed2005

Consistency of reported alcohol use by pregnant women: anonymous versus confidential questionnaires with item nonresponse differences.

BACKGROUND: Self-report is the best method to attain information about moderate alcohol consumption. However, reported alcohol consumption before and during pregnancy is sensitive to response bias. METHODS: We compared identical questionnaires completed either confidentially or anonymously by pregnant women. A representative half of the pregnant women in Oslo attending ultrasound screening between June 2000 and May 2001 were invited to join a confidential questionnaire study. Another group of pregnant women, selected in the identical manner, were asked to answer the same questionnaire anonymously during the summer of 2001. The questionnaire was completed by 1749 confidentially and 191 anonymously (response rate 93.4% vs 84.4%). For the current study, only women with Scandinavian ethnicity were included: 1707 and 178, respectively. Measures were T-ACE (screening measure for pregnancy risk drinking), reported frequency of alcohol use, Standard Units (SU) per occasion (po), SU per week, and binge drinking (>or=5 SU po), before and during pregnancy. RESULTS: There were no significant differences in reported alcohol consumption between the confidential and the anonymous group for the sample as a whole. Any alcohol consumption was reported by 22.6% and 23.3% during pregnancy week 7-12 and 13+ (confidential group) versus 22.5% and 25.8% (anonymous group). Differences between the groups tended to be larger for SU per week (p=0.07 both before pregnancy and after week 12 of pregnancy) than for the indirect alcohol (T-ACE) and the binge drinking questions. In the confidential group, the women with lower education had close to twice as high item nonresponse on the direct alcohol questions during pregnancy compared with those with higher education. This difference was smaller in the anonymous group. The rate of smoking was not reported differently in the anonymous group. CONCLUSIONS: Among pregnant women, there was no significant difference in self-reported alcohol consumption obtained by confidential or anonymous questionnaires.

Adult↗
PubMed2005

Blood pressure in the neonate: three non-invasive oscillometric pressure monitors compared with invasively measured blood pressure.

AIM: To compare blood pressure in neonates obtained from three different oscillometer blood pressure monitors (Dinamap, Criticare, Hewlett-Packard) with arterial blood pressure (Hewlett-Packard' invasive unit). STUDY DESIGN: A total of 32 randomized, non-invasive blood pressure series, each consisting of three measurements from each monitor, were obtained from 20 neonates (birthweight 531-4660 g). Each measurement was compared with the invasive pressure. RESULTS: Two factors appear to have a systematic effect on the difference between oscillometric and invasive pressure (the measurement deviance): the size of the infant, e.g., the arm circumference, and the monitor system. For small infants, the non-invasively measured value tends to be too high. The deviance is partly reversed for larger infants (dependency on size significant for mean and diastolic pressure, p < 0.001). The difference between monitor systems is clearly significant (p < 0.001). Hewlett-Packard gives the lowest pressure values for all pressures. Thus, Criticare and Dinamap tended to show values too high in the smallest infants, while Hewlett-Packard tended to give values too low in larger infants. Birthweight, present weight and arm circumference affected measurement deviance approximately equally strongly, while factors such as the infant's sex, need of breath support and umbilical or radial arterial line were non-significant. CONCLUSIONS: Blood pressure should preferably be measured invasively in severely ill neonates and preterm infants, being aware of pitfalls with measurements using different oscillometer monitors and the size/arm circumference of the infant.

Blood Pressure↗
PubMed2004

[Three special cases of pregnancy outcome to reflect about].

BACKGROUND: Neonatal alloimmune thrombocytopenia (NAITP) may be a serious condition with prenatal intracranial haemorrhages. Our three cases of serious NAITP raise the question of whether pregnant women should be screened for thrombocyte type and then for HPA-1a antibodies if they are HPA-1bb positive. CASE REPORTS: We present three cases of severe NAITP in which screening and follow up of HPA-1a antibodies prevented serious sequelae in two of the siblings. The first child was a stillbirth with congenital hydrocephalus caused by an intraventricular haemorrhage. In the second pregnancy, the mother was found to be platelet type HPA-1bb with platelet antibodies against HPA-1a. The antibody level was extremely high and an elective caesarean section was performed four weeks before term. The platelet count at birth was 3 and 5 x 10(9)/L and a transfusion of matched platelets was immediately performed followed by infusion of intravenous immunoglobulin. In the third pregnancy, an intracerebral haemorrhage was detected by ultrasound at 27 weeks of gestation. The mother was given steroids to induce foetal lung maturation followed by a caesarean section in week 28. The platelet count was 6 x 10(9)/L. The child was transfused with compatible platelets and given an infusion of intravenous immunoglobulin. OUTCOME: None of the two children have developed any psychomotor sequelae by the age of five and three years, respectively. The importance of screening for platelet type and anti-platelet antibodies and mode of delivery is discussed.

Adult↗
PubMed2003

[Mother-to-child transmission of HIV].

BACKGROUND: Modern treatment of HIV-positive women has reduced the rate of transmission of HIV to their children. The relative importance of different interventions is unclear. We have studied mother-to-child transmission from the start of the Norwegian epidemic in 1983 and up to the year 2000. MATERIAL AND METHODS: Retrospective study of risk factors in HIV-positive women and children of HIV-positive mothers born in Norway and followed up at our hospital. RESULTS: 53 women gave birth to 57 live-born children, eight of whom were HIV-infected. The mothers of 4 HIV-infected children were treated with zidovudine monotherapy during their pregnancy. Out of the 12 children delivered by elective caesarean section and the 17 children (8 delivered by elective caesarean section) with mothers receiving antiviral combination therapy, none were HIV-infected. HIV-RNA was measured at the time of birth in 16 women; 8 had viral loads of less than 50 copies/ml and 8 had viral loads at the time of delivery between 50 and 57 100 copies/ml, but none of these 16 transmitted the virus to their children. None of the mothers breast-fed. INTERPRETATION: Transmission of HIV from mother to child was associated with insufficient or no antiviral therapy of mother and child. The effect of elective caesarean section could not be separated from the effect of antiviral therapy. We did not find any association between transmission of HIV and prematurity, development of immunodeficiency in the mother, special risk group status, or early membrane rupture.

Anti-HIV Agents↗