Biomedical subjects

Rolf Ulrich

Publications and source records attributed to Rolf Ulrich.

13 recordsLinked to original sources

PubMed2005

Anabolic ergogenic substance users in fitness-sports: a distinct group supported by the health care system.

BACKGROUND: Anabolic ergogenic substance use, in particular the use of anabolic androgenic steroids, is a serious problem in general. Nevertheless, it is subject to debate whether ergogenic substance users exhibit similar features as multiple substance users or whether they constitute a discrete group. METHODS: One thousand eight hundred and two standardized, anonymous questionnaires were distributed among visitors of 113 fitness centers. Questions were asked concerning biometric parameters, social indicators, physical fitness, use of natural stimulants, general illicit drugs and ergogenic substances. With logistic regression analysis, multivariate odds ratios were estimated to investigate the association of anabolic ergogenic substance or general illicit drug use with other parameters. RESULTS: 13.5% of all participants confessed to having used anabolic ergogenic substances at some point in time. Anabolic ergogenic substance use was positively related with cocaine use, training years, training frequency, negatively related to the level of education, alcohol intake and less frequently used by Germans than by non-Germans. General illicit drug use, however, was positively related with alcohol intake, smoking and a university degree and negatively with having children. In addition, anabolic ergogenic substance use was significantly related with the use of general illicit drugs based on the strong relation with the use of cocaine, which is an ergogenic substance itself. The health care system supplies 48.1% of the anaolic ergogenic substance users with their substances and 32.1% are even monitored by a physician. CONCLUSIONS: The results of this study strengthen the notion that anabolic ergogenic substance users constitute a specific body-oriented substance user group. Uncommon for general illicit drug use, the health care system is a major sponsor of anabolic ergogenic substance users. These findings suggest the need for alternative approaches for successful prevention and intervention programs.

Adult↗

PubMed2005

No evidence for qualitative differences in the processing of short and long temporal intervals.

Several lines of research suggest that two distinct timing mechanisms are involved in temporal information processing: a sensory mechanism for processing of durations in the range of milliseconds and a cognitively controlled mechanism for processing of longer durations. The present study employed a dual-task approach and a sensory interference paradigm to further elucidate the distinct timing hypothesis. Experiment 1 used mental arithmetic as a nontemporal secondary task, Experiment 2 a memory search task, and Experiment 3 a visuospatial memory task. In Experiment 4, a loudness manipulation was applied. Mental arithmetic and loudness manipulation affected temporal discrimination of both brief and long intervals, whereas the two remaining tasks did not influence timing performance. Observed differences in interference patterns may be explained by some tasks being more difficult than others. The overall pattern of results argues against two qualitatively distinct timing mechanisms, but is consistent with attention-based cognitive models of human timing.

Adult↗

PubMed2004

Perceived duration of expected and unexpected stimuli.

Three experiments assessed whether perceived stimulus duration depends on whether participants process an expected or an unexpected visual stimulus. Participants compared the duration of a constant standard stimulus with a variable comparison stimulus. Changes in expectancy were induced by presenting one type of comparison more frequently than another type. Experiment 1 used standard durations of 100 and 400 ms, and Experiments 2 and 3 durations of 400 and 800 ms. Stimulus frequency did not affect perceived duration in Experiment 1. In Experiments 2 and 3, however, frequent comparisons were perceived as shorter than infrequent ones, and discrimination performance was better for infrequent comparisons. Overall, this study supports the notion that infrequent stimuli increase the speed of an internal pacemaker.

Adult↗

PubMed2004

On the locus of speed-accuracy trade-off in reaction time: inferences from the lateralized readiness potential.

Lateralized readiness potentials (LRPs) were used to determine the stage(s) of reaction time (RT) responsible for speed-accuracy trade-offs (SATs). Speeded decisions based on several types of information were examined in 3 experiments, involving, respectively, a line discrimination task, lexical decisions, and an Erikson flanker task. Three levels of SAT were obtained in each experiment by adjusting response deadlines with an adaptive tracking algorithm. Speed stress affected the duration of RT stages both before and after the start of the LRP in all experiments. The latter effect cannot be explained by guessing strategies, by variations in response force, or as an indirect consequence of the pre-LRP effect. Contrary to most models, it suggests that SAT can occur at a late postdecisional stage.

Adult↗

PubMed2004

On the correlation of a naturally and an artificially dichotomized variable.

A method is suggested for estimating the correlation of a naturally (X) and an artificially (Y) dichotomized variable. It is assumed that a normal random variable (L) underlies the artificially dichotomized variable. The proposed correlation coefficient recovers the product moment correlation coefficient between X and L from a fourfold table of X and Y. The suggested correlation coefficient nu is contrasted with the phi correlation and the biserial eta. The biserial eta was proposed by Karl Pearson and is conceptually related to the new correlation coefficient. However, in addition, Pearson's biserial eta invokes the assumption that the marginal distribution of L is normal, which contradicts its basic assumptions and thus does not recover the true correlation of L and X. Finally, an approximation is provided to simplify the calculation of nu and its standard error.

Humans↗

PubMed2004

Threshold estimation in two-alternative forced-choice (2AFC) tasks: the Spearman-Kärber method.

The Spearman-Kärber method can be used to estimate the threshold value or difference limen in two-alternative forced-choice tasks. This method yields a simple estimator for the difference limen and its standard error, so that both can be calculated with a pocket calculator. In contrast to previous estimators, the present approach does not require any assumptions about the shape of the true underlying psychometric function. The performance of this new nonparametric estimator is compared with the standard technique of probit analysis. The Spearman-Kärber method appears to be a valuable addition to the toolbox of psychophysical methods, because it is most accurate for estimating the mean (i.e., absolute and difference thresholds) and dispersion of the psychometric function, although it is not optimal for estimating percentile-based parameters of this function.

Choice Behavior↗

PubMed2004

Effects of redundant visual stimuli on temporal order judgments.

Four experiments were conducted in order to compare the effects of stimulus redundancy on temporal order judgments (TOJs) and reaction times (RTs). In Experiments 1 and 2, participants were presented in each trial with a tone and either a single visual stimulus or two redundant visual stimuli. They were asked to judge whether the tone or the visual display was presented first. Judgments of the relative onset times of the visual and the auditory stimuli were virtually unaffected by the presentation of redundant, rather than single, visual stimuli. Experiments 3 and 4 used simple RT tasks with the same stimuli, and responses were much faster to redundant than to single visual stimuli. It appears that the traditional speedup of RT associated with redundant visual stimuli arises after the stimulus detection processes to which TOJs are sensitive.

Adult↗

PubMed2004

A computer program for Spearman-Kärber and probit analysis of psychometric function data.

PMETRIC is a computer program for the analysis of observed psychometric functions. It can estimate the parameters of these functions, using either probit analysis (a parametric technique) or the Spearman-Kärber method (a nonparametric one). For probit analysis, either a maximum likelihood or a minimum chi 2 criterion may be used for parameter estimation. In addition, standard errors of parameter estimates can be estimated via bootstrapping. The program can be used to analyze data obtained from either yes-no or m-alternative forced-choice tasks. To facilitate the use of PMETRIC in simulation work, an associated program, PMETGEN, is provided for the generation of simulated psychometric function data. Use of PMETRIC is illustrated with data from a duration discrimination task.

Computer Simulation↗

PubMed2003

Simple reaction time and statistical facilitation: a parallel grains model.

A race-like model is developed to account for various phenomena arising in simple reaction time (RT) tasks. Within the model, each stimulus is represented by a number of grains of information or activation processed in parallel. The stimulus is detected when a criterion number of activated grains reaches a decision center. Using the concept of statistical facilitation, the model accounts for many classical effects on mean simple RT, including those of stimulus area, stimulus intensity, stimulus duration, criterion manipulations, redundant stimuli, and the dissociation between intensity effects on simple RTs and temporal order judgments. The model is also consistent with distributional properties of simple RTs.

Humans↗

PubMed2003

Temporal organization of covert motor processes during response selection and preparation.

Onset of a movement-related brain potential (lateralized readiness potential, LRP) was used to divide reaction time (RT) into two intervals: (1) stimulus onset to LRP onset, and (2) LRP onset to onset of the overt response. Effects on these intervals of advance information about the to-be-signaled response and of the mapping between fingers and response buttons were examined. These effects were used to reach conclusions about the organization of response preparation and about the identity of the processes influenced by advance information. In the absence of advance information, response preparation involved two steps. First, two of the four possible response alternatives were prepared, then one of these two was prepared further. Which pair of responses was prepared during the first step depended on the spatial arrangement of the fingers on the buttons, rather than on any common anatomical feature. Advance information about the upcoming response allowed the first step to be performed prior to the response signal, thus removing its contribution to RT. The second step, however, remained unaffected.

Arousal↗

PubMed2003

Dynamics of sensorimotor cortex activation to spatial sounds precueing ipsi- versus contralateral manual responses.

Spatially informative visual precues give rise to event-related potential asymmetries with higher negativities over the contralateral hemisphere. However the attribution of these potentials to sensorimotor areas is still unclear. The present magnetoencephalography study assessed movement preparation processes to auditory spatial precues. Event-related desynchronization (ERD) was measured to test the hypothesis that lateralized sounds would give rise to a fast, stimulus-driven activation of motor networks independent of the precued response side. The lateralized vowels /a/ and /e/ served as precues for either ipsi- or contralateral responses, respectively, which had to be executed when an imperative stimulus was presented 1 s after precue onset. Two separate experiments were conducted with either blocked or mixed presentation of ipsi- and contralateral precues. Beta ERD over sensorimotor regions representing the stimulus side was elicited by both types of precues approximately 200 ms after their onset. For contralateral precues, a switch of beta ERD to the response hemisphere took place approximately 400 ms after trial-onset, peaking prior to the imperative stimulus (approximately 800 ms post trial-onset). Signal subspace projection demonstrated a high topographical correspondence between the early precue-related ERD and the pattern immediately preceding the response, suggesting that both were generated in similar motor networks. Apparently lateralized sounds give rise to an early activation of contralateral motor networks independent of the precued response. This suggests strong associations between space processing and action preparation networks, with fast activations preceding a detailed cortical analysis of stimulus meaning.

Adult↗

PubMed2003

Locus of the effect of temporal preparation: evidence from the lateralized readiness potential.

It is well established that reaction time (RT) is shorter when a response signal is preceded by a warning signal, because the warning signal causes the participant to prepare for the upcoming response. A review of chronometric and psychophysiological studies reveals the prevailing view that this temporal preparation operates mainly at a motor level speeding up rather late processes. To assess the locus of this preparation effect, we conducted two experiments employing the lateralized readiness potential (LRP). Contrary to this prevailing view, the results of both experiments clearly indicate that temporal preparation enhances the processing speed of relatively early processes, because a manipulation of temporal uncertainty affected RT, the P300 latency, and the stimulus-to-LRP interval but not the LRP-to-keypress interval.

Adult↗

PubMed2002

Stimulus-response compatibility in intensity-force relations.

Romaiguère, Hasbroucq, Possamaï, and Seal (1993) reported a new compatibility effect from a task that required responses of two different target force levels to stimuli of two different intensities. Reaction times were shorter when high and low stimulus intensities were mapped to strong and weak force presses respectively than when this mapping was reversed. We conducted six experiments to refine the interpretation of this effect. Experiments 1 to 4 demonstrated that the compatibility effect is clearly larger for auditory than for visual stimuli. Experiments 5 and 6 generalized this finding to a task where stimulus intensity was irrelevant. This modality difference refines Romaiguère et al.'s (1993) symbolic coding interpretation by showing that modality-specific codes underlie the intensity-force compatibility effect. Possible accounts in terms of differences in the representational mode and action effects are discussed.

Adult↗