Biomedical subjects

Ronald J Place

Publications and source records attributed to Ronald J Place.

12 recordsLinked to original sources

PubMed2006

Caring for non-combatants, refugees, and detainees.

The recently reported abuses at Abu Ghraib prison have brought the issue of medical care for displaced persons (DPs) to greater prominence. Natural disasters in the United States (eg, Hurricane Katrina) and elsewhere also require significant medical resources in situations that lack basic infrastructure. Intimate knowledge of the basic tenets of international law is crucial to the care of DPsin any capacity. This article provides an introduction to the Geneva Conventions and the medical and administrative issues that form a framework on which to base DP care.

Codes of Ethics↗

PubMed2005

The effect of combat rations on bowel habits in a combat environment.

BACKGROUND: Combat rations have long been suspected to affect the bowel habits of deployed soldiers by causing significant constipation. This may create morbidity and result in decreased troop readiness. In a uniform population of deployed combat soldiers, we sought to determine the effect of combat rations on changes in bowel habits. METHODS: Over a 4-month period from December 2001 through March 2002, 118 soldiers were followed prospectively using a bowel habit diary. Soldiers were evaluated by age, race, gender, past medical history, ration intake, and medications including fiber use. Subjects were then screened for changes in diarrhea and constipation. We performed an analysis to determine predictors for changing habits. RESULTS: There were 108 males and 10 females. Mean follow-up was 42.6 +/- 23.1 days. Groups were comparable in demographics, time in the combat zone, and fluid/fiber intake (P = not significant [NS]). No change in habits were found in 58%, 19% had an increase in constipation, 13% had an increase in diarrhea, and 10% had increase in both diarrhea and constipation, while 8% had improvements. CONCLUSION: Combat rations and environment have variable effects on bowel habits, with no loss in workdays. Although 64% of subjects experienced either no change or improvement, and 36% had worsened symptoms, this appears unrelated to ration or fiber intake.

Adult↗

PubMed2005

Supporting the Global War on Terror: a tale of two campaigns featuring the 250th Forward Surgical Team (Airborne).

BACKGROUND: Forward Surgical Teams (FSTs) are 20-person units designed to perform front-line, life-saving combat surgery. This study compares the employment, injuries encountered, and workload of an airborne FST in two widely varying campaigns. METHODS: The 250th FST provided far forward surgery for initial entry assaults and follow-on stability operations in Afghanistan (Operation Enduring Freedom [OEF]) and northern Iraq (Operation Iraqi Freedom [OIF]). Prospective data on all patients admitted to the 250th were analyzed. Data from civil affairs missions were evaluated retrospectively. RESULTS: In supporting combat operations, 127 surgical procedures (OEF: 68, OIF: 59) were performed on 98 patients (OEF: 50, OIF: 48) during 17 months deployed (OEF: 6, OIF: 11). After initial assaults, stability actions varied significantly in terms of civil affairs missions (OEF: 3, OIF: 161). CONCLUSIONS: Although the number and types of combat casualties were similar between the campaigns, employment of the FST changed dramatically in OIF because of increased medical reconstruction missions.

Afghanistan↗

PubMed2004

Outcome of HIV-infected patients with invasive squamous-cell carcinoma of the anal canal in the era of highly active antiretroviral therapy.

PURPOSE: Before the development of highly active antiretroviral therapy for the treatment of HIV infection, HIV patients diagnosed with invasive squamous-cell carcinoma of the anal canal carried a very poor prognosis. This study was designed to determine the outcome in a similar group of patients in the era of highly active antiretroviral therapy. METHODS: HIV-positive patients treated for invasive squamous-cell carcinoma of the anal canal at the University of Texas Medical Center affiliated hospitals from 1980 to 2001 were identified from operative data and cancer registries. We reviewed these records and collected data regarding age, CD4 count, highly active antiretroviral therapy, cancer treatment, complications, and survival. The patients were divided into two groups based on the presence or absence of highly active antiretroviral therapy and compared using a Kaplan-Meier approach. RESULTS: Fourteen patients with HIV and invasive squamous-cell carcinoma of the anal canal were identified. Six were in the prehighly active antiretroviral therapy group and eight in the highly active antiretroviral therapy group. All were considered for treatment with chemotherapy and radiation. In the prehighly active antiretroviral therapy group, one patient refused therapy and three were unable to complete the squamous-cell carcinoma therapy as planned because of complications. Four of eight highly active antiretroviral therapy patients were unable to complete the squamous-cell carcinoma therapy as planned. The prehighly active antiretroviral therapy patients had a mean age of 40 years and a mean CD4 count of 190 at the time of diagnosis. The highly active antiretroviral therapy patients had a mean age of 44 years and a mean CD4 count of 255 at the time of diagnosis. The 24-month survival was 17 percent in the prehighly active antiretroviral therapy group and 67 percent in the highly active antiretroviral therapy group (P = 0.0524). All six patients in the prehighly active antiretroviral therapy group died with active squamous-cell carcinoma vs. two in the highly active antiretroviral therapy group. Four of the remaining six patients had no evidence of active squamous-cell carcinoma at the last follow-up visit. CONCLUSIONS: A review of patients with HIV and invasive squamous-cell carcinoma of the anal canal suggests a trend toward a higher CD4 count at the time of diagnosis and improved survival in patients receiving highly active antiretroviral therapy. In this new era, HIV-positive patients should be on highly active antiretroviral therapy. If not, highly active antiretroviral therapy should be initiated, and standard multimodality therapies for invasive squamous-cell carcinoma of the anal canal are recommended.

Adult↗

PubMed2004

An active duty woman with anal incontinence after vaginal delivery: an elusive diagnosis.

Anal sphincter injury as a result of birth trauma is the leading cause of fecal incontinence in women presenting to surgical clinics. A 36-year-old active duty woman was referred to the Urogynecology Clinic at Madigan Army Medical Center for evaluation of a deficient perineal body. She reluctantly reported a 12-year history of anal incontinence since the birth of her first child, predating her entry into the naval service. Examination revealed defects of the perineum and anal sphincter resembling a cloacal deformity. Uncomplicated overlapping anal sphincteroplasty and perineorrhaphy were performed, restoring perineal anatomy and continence. Anal incontinence and other anatomic defects attributable to lacerations sustained at childbirth may go undetected during routine screening examinations. Interview and examination techniques should be emphasized in primary care settings.

Adult↗

PubMed2004

In-flight transfusion of packed red blood cells on a combat search and rescue mission: a case report from operation enduring freedom.

Injuries on the battlefield can occur far from the nearest medical treatment facility. This is especially likely for downed pilots and special operations personnel. Some of these injuries lead to significant blood loss requiring transfusion. We present two cases of injured coalition force members during Operation Enduring Freedom that illustrate the potential need for a transfusion capability at the site of injury to prevent death. Consideration should be given to augmenting transfusion capabilities in military environments with predictably long evacuation times.

Afghanistan↗

PubMed2004

Heterotopic gastric mucosa of the anus: a case report and review of the literature.

Ectopic gastric mucosa has been described at various locations of the body, including all levels of the gastrointestinal tract. However, this finding is rare in the rectum and anus, with 38 reported cases. In only six cases, including the present one, has the heterotopic tissue been located within 2 cm of the dentate line. We report a case of gastric heterotopia discovered in a 21-year-old male who presented with anal pain and pruritus. Flexible sigmoidoscopy demonstrated an anal polyp, and biopsy confirmed fundic-type gastric tissue. A (99m)technetium-pertechnetate scan confirmed increased uptake in the anus. After minimal clinical improvement with proton-pump inhibitors, the patient underwent local surgical excision and remains symptom-free at a follow-up of 9 months. We review the potential etiologies, clinical manifestations, treatment options, and patient outcomes.

Adult↗

PubMed2002

Flexible endorectal ultrasound for predicting pathologic stage of rectal cancers.

BACKGROUND: Endorectal ultrasound (ERUS) is an accurate method for preoperative staging of rectal cancers. Most often, a rigid 360-degree rotating probe is used. We studied whether flexible probes could attain equivalent accuracy for bowel wall penetration. METHODS: Forty-five patients were prospectively evaluated with flexible devices. Results were compared with 20 rigid and 10 flexible probe studies. To assess learning curves, we used logistic regression analysis and coefficients of correlation on accuracy data to compare ERUS accuracy with the number of examinations. RESULTS: Level of invasion was correct in 49%. Nodal examinations were correct in 78%. Learning curves leveled out at 100 examinations with 87% accuracy for the rigid probe (R = 0.46) and 77% for the flexible devices (R = 0.31). CONCLUSIONS: The coefficient of correlation for each method portends a more reliable learning curve for the rigid devices. Flexible devices were less accurate for level of invasion than the literature reported for rigid devices.

Adenocarcinoma↗

PubMed2002

Diverticular disease.

Diverticular disease is a common finding in Western countries with an increasing prevalence with age. Many patients with the disorder remain asymptomatic. However, up to 30% of those affected may show clinical signs including pain, bleeding, obstruction, abscess, fistulae and perforation. The purpose of this chapter is to review the epidemiology, pathogenesis, clinical presentation, diagnostic regimens and treatment options for this disorder.

Aged↗

PubMed2002

Gynecomastia: complications of the subcutaneous mastectomy.

Gynecomastia is a benign enlargement of the male breast secondary to gland proliferation. Subcutaneous mastectomy is performed for symptomatic patients and in those desiring cosmetic changes. The aim of this study was to assess the risk factors and complications associated with the operation. We retrospectively examined the records of all patients undergoing a subcutaneous mastectomy for gynecomastia. Ninety-one patients were identified. We conducted telephone interviews with 52 patients and performed 65 subcutaneous mastectomies on those 52 patients. Thirty of the 65 procedures (46%) developed complications. These included sensory changes, pain, seromas, scarring, breast asymmetry, hematomas, and wound infection. No preoperative risk factors were significant for postoperative complications. Eighteen of 22 cases with drains placed intraoperatively developed complications as compared with 12 of 43 cases without drains (P = 2.6 x 10(-7)). Specimens removed from the patients who had drains placed were significantly larger than those from patients who did not have drains placed (P = 1.5 x 10(-5)). However, specimen size was not an independent risk factor for development of a complication (P = 0.14). We found a relatively high complication rate in subcutaneous mastectomy for gynecomastia. Most complications are minor with no long-term effect. Drain placement was the only risk factor associated with postoperative complications.

Adolescent↗

PubMedDate not supplied

Forward surgical team (FST) workload in a special operations environment: the 250th FST in Operation ENDURING FREEDOM.

PURPOSE: Forward Surgical Teams (FST) deploy to support conventional combat units of at least regimental size. This report examines the injuries and treatments of an FST in an environment of unconventional tactics, limited personal protection, and extended areas of responsibility during Operation ENDURING FREEDOM. METHODS: A prospective evaluation of the personal protective measures, mechanisms of injury, types of injuries, and times to treatment in Operation ENDURING FREEDOM. Additionally, per-surgeon caseloads, operative interventions, and outcomes are examined. The first phase of this deployment involved co-locating with an Air Force Expeditionary Medical Squadron at Seeb Air Base, Oman (SABO). The second phase involved stand-alone operations at Kandahar International Airport (KIA). Participants include U.S. Special Forces, conventional U.S forces, coalition country special forces, and anti-Taliban Afghan soldiers. RESULTS: During the deployment, the FST performed 68 surgical procedures on 50 patients (19 SAB, 31 KIA). There were 35 orthopedic cases (2 to 28 per surgeon), 30 general surgery cases (2 to 10 per surgeon), and 3 head/neck cases. Mechanism of injury included non-battle injury (13), bomb blast (13), gunshot wounds (8), mine (8), and grenades (5). Primary injuries were to the extremities in 27, torso in 9, and head/neck in 11. Three patients had appendicitis. Five patients were wearing body armor, whereas 4 wore helmets. The mean Relative Trauma Score was 7.4. Thirty-one patients were treated at KIA with a mean time to operative treatment of 2.7 +/- 2.7 hours, whereas 19 were treated in SABO with a mean time to operative treatment of 12.4 +/- 15.1 hours. Nine patients received transfusions. Three nonoperative patients died of wounds. CONCLUSION: Despite the lack of personal protective gear, most patients had extremity wounds as their primary injuries. In this special operations environment, time to operative treatment was significantly longer than expected.

Afghanistan↗

PubMedDate not supplied

Superior mesenteric vein thrombosis following laparoscopic Nissen fundoplication.

This report describes the second case of a superior mesenteric and portal vein thrombosis following an uneventful laparoscopic Nissen fundoplication. The patient presented on postoperative day 10 with acute onset of abdominal pain and inability to tolerate oral food. A computed tomography (CT) scan revealed superior mesenteric and portal venous thrombosis with questionable viability of the proximal small bowel. He was heparinized and taken for emergent exploratory laparotomy. At surgery and at a planned re-exploration the following day, the bowel was viable and no resection was needed. Despite continuation on anticoagulation therapy, he developed a pulmonary embolism. A hypercoagulable workup was normal. After continued anticoagulation therapy and supportive care, a duplex ultrasound 2 months after the event showed normal flow in both the superior mesenteric and portal veins. Possible mechanisms are discussed along with a review of the pertinent literature.

Adult↗