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Biomedical subjects

Ross D Crosby

Publications and source records attributed to Ross D Crosby.

At least 19 recordsLinked to original sources

The application of ecological momentary assessment to the study of night eating.

OBJECTIVE: Night eating syndrome (NES) was first described in 1955 by Albert Stunkard and colleagues. NES consists of either overeating at night or waking up during the night and eating. METHOD: In the current study we used ecological momentary assessment (EMA) to describe 14 self-defined night-eaters. The participants in the current study completed an EMA protocol of approximately two weeks. RESULTS: We found that ratings of hunger appeared to be higher during night awakenings than in the evening. Also, both affect and arousal generally decreased throughout the day and were lowest during awakening episodes. CONCLUSION: The current study adds interesting data in describing the experience of night-eating behavior with ecological momentary assessments from self-described night-eaters.

Adult↗

Long-term clinical and neuropsychological outcomes of West Nile virus infection.

BACKGROUND: Since its introduction in 1999, West Nile virus has rapidly become the most common arboviral infection in North America. Little is known about the long-term clinical sequelae of West Nile virus infection. METHODS: A total of 49 patients with laboratory-confirmed West Nile virus infection were identified through state-based surveillance. Stratification for disease severity was based on hospitalization during the infection episode. Assessment occurred a mean of 13 months after diagnosis. Medical records were reviewed, and a complete neurologic examination was performed. Standardized surveys for quality of life, functional ability, fatigue, and depression were performed for all subjects. An extensive battery of neuropsychological tests was performed to assess cognitive function. RESULTS: Self-reported fatigue, memory problems, extremity weakness, word-finding difficulty, and headache were common complaints. Standardized survey data confirmed an overall sense of poor physical health, fatigue, depression, and moderate-to-severe disability in 24 (49%), 24 (49%), 12 (24%), and 4 (8%) patients, respectively. New tremor was seen or reported for 10 (20%) of the patients. Neuropsychological testing showed abnormalities of motor skills, attention, and executive functions. Univariate analysis of multiple risk factors did not identify any predictors of adverse outcomes. CONCLUSIONS: Multiple somatic complaints, tremor, and abnormalities in motor skills and executive functions are common long-term problems among patients who have had West Nile virus infection. Patients with milder illness are just as likely as patients with more-severe illness to experience adverse outcomes.

Aged↗

The relationship of momentary anger and impulsivity to bulimic behavior.

Past research has suggested that negative affect may be a causal factor for eating disordered behaviors. More specifically, research has shown that anger appears to be one aspect of negative affect that is particularly relevant in bulimic patients. Previous studies have also shown that the relationship between negative affect and eating disordered behaviors may partially depend upon personality variables such as impulsivity. The present study examined whether the relationship between anger and eating disordered behaviors is moderated by impulsivity. Subjects completed an ecological momentary assessment (EMA) protocol for an average of 2 weeks. Findings revealed that overall antecedent anger level and the variability of antecedent anger predicted binge-eating episodes and that these relationships were moderated by participants' level of impulsivity. These findings suggest that personality variables impact the way that anger and eating behaviors relate. They also suggest that the variability of antecedent anger may be a fruitful avenue for future research for those interested in causal variables associated with bulimia nervosa.

Adolescent↗

Cognitive behavioral therapy for compulsive buying disorder.

To our knowledge, no psychotherapy treatment studies for compulsive buying have been published. The authors conducted a pilot trial comparing the efficacy of a group cognitive behavioral intervention designed for the treatment of compulsive buying to a waiting list control. Twenty-eight subjects were assigned to receive active treatment and 11 to the waiting list control group. The results at the end of treatment showed significant advantages for cognitive behavioral therapy (CBT) over the waiting list in reductions in the number of compulsive buying episodes and time spent buying, as well as scores on the Yale-Brown Obsessive Compulsive Scale--Shopping Version and the Compulsive Buying Scale. Improvement was well-maintained at 6-month follow-up. The pilot data suggests that a cognitive behavioral intervention can be quite effective in the treatment of compulsive buying disorder. This model requires further testing.

Adult↗

Does the avoidance of body and shape concerns reinforce eating disordered attitudes? Evidence from a manipulation study.

It is theoretically plausible to assume that attention plays a role in eating disordered attitudes. Indeed, studies examining relations between eating disorders and attention to body and/or shape related stimuli have found such associations. Although this research is invaluable in characterizing relations between attentional processes and eating disordered attitudes, such work remains correlational in nature. In the present investigation, 73 undergraduate women were randomly assigned to one of two attentional training conditions. One condition trained attention away from body/shape words, whereas the other trained attention toward body/shape words. Following this training participants reported on their eating-related attitudes. Women trained to avoid body/shape words subsequently reported more concerns about eating and body shape. These results suggest that attentional avoidance of body/shape concerns increases such concerns. The results point to the potential causal effects of attention on eating disordered attitudes, in turn suggesting a basis for possible treatment.

Adult↗

Use of latent profile analysis to identify eating disorder phenotypes in an adult Australian twin cohort.

CONTEXT: The relationships among the different eating disorders that exist in the community are poorly understood, especially for residual disorders in which bingeing or purging occurs in the absence of other behaviors. OBJECTIVE: To examine a community sample for the number of mutually exclusive weight and eating profiles. DESIGN: Data regarding lifetime eating disorder symptoms and weight range were submitted to a latent profile analysis. Profiles were compared regarding personality, current eating and weight, retrospectively reported life events, and lifetime depressive psychopathology. SETTING: Longitudinal study among female twins from the Australian Twin Registry in whom eating was assessed by a telephone interview. PARTICIPANTS: A community sample of 1002 twins (individuals) who had participated in earlier waves of data collection. MAIN OUTCOME MEASURES: Number and clinical character of latent profiles. RESULTS: The best fit was a 5-profile solution with women who were (1) of normal weight with few lifetime eating disorders (4.3%), (2) overweight (10.6% had a lifetime eating disorder), (3) underweight and generally had no eating disorders except for 5.3% who had restricting anorexia nervosa, (4) of low to normal weight (89.0% had a lifetime eating disorder), and (5) obese (37.0% had a lifetime eating disorder). Each profile contained more than 1 type of lifetime eating disorder except for the third profile. Women in the first and third profiles had the best functioning, with women in the fourth and fifth profiles having similarly poorer functioning. The women in the fourth group had a symptom profile distinctive from the other 4 groups in terms of severity; they were also more likely to have had lifetime major depression and suicidality. CONCLUSION: Lifetime weight ranges and the severity of eating disorder symptoms affected clustering more than the type of eating disorder symptom.

Adult↗

An empirical analysis of eating disorders and anxiety disorders publications (1980-2000)--part I: Research methods.

OBJECTIVE: The current study compared the eating disorder and anxiety disorder literature in terms of research design and methodologic features in 1980, 1990, and 2000. METHOD: Computer literature searches were conducted using PubMed and PsychInfo databases to identify relevant eating disorder and anxiety disorder articles published at each of the three time points. A total of 456 articles were randomly selected, including 228 articles from the eating disorder literature and the anxiety disorder literature. Within each specific literature, one third (76) of the articles were selected from each of the three time points (1980, 1990, 2000). Two raters, from a team of eight trained raters, were randomly assigned to independently rate each article in terms of 75 separate methodologic features. Disagreements in ratings were resolved via consensus. Ratings were tabulated separately for eating disorders and anxiety disorders across the three time points. RESULTS: Although there were some differences between anxiety disorders and eating disorders, most of the variables did not substantially differ between these two fields. There was a consistent trend for both fields to show increases in more rigorous methodologies over time. However, both the eating disorder literature and the anxiety disorder literature were characterized by a pervasive absence of many recommended methodologic procedures across the past two decades. CONCLUSION: Although the eating disorder literature and the anxiety disorder literature are increasingly characterized by improved reporting of rigorous methodologic procedures, there is still a pervasive absence of such procedures in both literatures, which limits the strength of inference in these studies.

Anxiety Disorders↗

An empirical analysis of eating disorders and anxiety disorders publications (1980-2000)--part II: Statistical hypothesis testing.

OBJECTIVE: The current study compared the eating disorder literature and the anxiety disorder literature in terms of statistical hypothesis testing features in 1980, 1990, and 2000. METHOD: Computer literature searches were conducted using PubMed and PsychInfo databases to identify relevant eating disorder and anxiety disorder articles published at each of the three time points. A total of 456 articles were randomly selected, including 228 articles each from the fields of eating disorders and anxiety disorders. Within each field, one third (76) of the articles were selected from each of the three time points. Two raters, from a team of eight trained raters, were randomly assigned to independently rate each article in terms of 75 separate methodologic features. In the current article, we will emphasize the findings about hypothesis testing and statistical analysis. Disagreements in ratings were resolved via consensus. Ratings were tabulated separately by field across the three time points. RESULTS: Few differences were observed between eating disorder and anxiety disorder publications in terms of statistical hypothesis testing features. Although increases were observed in both fields in a number of areas from 1980 to 2000, there remains a pervasive absence of many of the statistical hypothesis testing features recommended by the American Psychological Association Task Force on Statistical Inference. CONCLUSION: These results are discussed in terms of their implications for the fields of eating disorders and anxiety disorders, for researchers, for reviewers, and for professional journals and editorial boards.

Anxiety Disorders↗

Development and psychometric validation of an eating disorder-specific health-related quality of life instrument.

OBJECTIVE: Health-related quality of life (HRQOL) has been used increasingly as an outcome measure in clinical research. Although the generic quality of life instruments has been used in previous research, disease-specific instruments offer greater sensitivity and responsiveness to change than generic instruments. No such disease-specific instrument is currently available that applies to eating-disordered samples. METHOD: The current article reports on the development and validation of the Eating Disorders Quality of Life (EDQOL) instrument, a disease-specific HRQOL self-report questionnaire designed for disordered eating patients. RESULTS: The EDQOL demonstrates excellent psychometric properties. CONCLUSION: The application of the EDQOL as an outcome measure in eating disorder research is considered.

Adolescent↗

A survey of herbal and alternative medication use among participants with eating disorder symptoms.

OBJECTIVE: The purpose of this survey was to collect data on herbal use in participants with eating disorder symptoms. METHOD: A survey was administered to 100 participants who had either sought treatment at the Eating Disorder Institute (EDI) or had been enrolled in previous research as the result of eating disorder symptoms. RESULTS: Of the 100 participants, 64% used an herbal product for weight loss. The mean monthly expenditure on herbs over the past year was 33.88 dollars +/- 41.10 dollars, with a range of 2 dollars-200 dollars. Dexatrim (Chattem, Chattanooga, TN; N = 27) and St. John's Wort (N = 19) had the highest reported use. Magazines were the most common source of product information (38.3%), with health care professionals being reported less frequently as the source of information. Knowledge of ephedra-related adverse effects was variable, and depended on a previous history of use. The majority (62.3%) of herb users reported an adverse effect. CONCLUSION: Herbal use is frequent among those with eating disorder symptoms, often resulting in substantial financial cost. Health professionals are rarely the source of herbal information. Therefore, there is ample room for educational interventions, which may result in the safer use of herbal products.

Adult↗

Nighttime eating: a descriptive study.

OBJECTIVE: The definition of night eating syndrome (NES) is inconsistent across various studies and literatures. The goal of the current descriptive study was to collect data on participants who were selected using broad criteria for nighttime eating. Researchers have cogently argued for consideration of wide ranges including "subsyndromal" cases before reifying diagnostic constructs prematurely. METHOD: One-hundred six participants with broadly defined nighttime eating problems were recruited through newspaper advertisements and were interviewed over the phone. The following instruments were administered: the Night Eating Questionnaire, the Night Eating Syndrome History and Inventory, the Eating Disorder Questionnaire, the Structured Clinical Interview for DSM-IV diagnoses and a Sleep Disorder Questionnaire. RESULTS: Thirty-one (29.2%) participants met the original criteria described by Stunkard et al. (Am J Med 1955;19:78) and only 14 (13.2%) participants met all of the most recent proposed criteria for NES (Birketvedt et al., JAMA 1999;282:657). The overlap between binge eating disorder (BED) and nighttime eating problems was modest in our sample with only 9 participants meeting current BED criteria. One half of our sample was obese. Regular nocturnal eating was reported by 57.5% of the participants. Dieting was not a frequent precursor or antecedent of nocturnal eating. However, self-reported current parasomnias were quite frequent in our sample. CONCLUSION: Our descriptive study confirms some of the observations made by other researchers. Nevertheless, nighttime eating is still an evolving concept that requires close collaboration between eating and sleep researchers.

Anorexia↗

Personality traits after recovery from eating disorders: do subtypes differ?

OBJECTIVE: We compared individuals recovered from anorexia (AN) and bulimia nervosa (BN) to determine characteristics that are shared by or distinguish eating disorder (ED) subtypes. METHOD: Sixty women recovered for > or = 1 year from AN or BN were compared with 47 control women (CW). Assessments included the Yale-Brown-Cornell Eating Disorder Scale, the Spielberger State-Trait Anxiety Inventory, the Beck Depression Inventory, the Yale-Brown Obsessive Compulsive Scale, the Temperament and Character Inventory, and Structured Clinical Interviews for DSM-IV. RESULTS: Individuals recovered from an ED had similar scores for mood and personality variables that were significantly higher than the scores for CW. Few recovered subjects had Cluster B personality disorder. Most individuals recovered within 6 years of their ED onset. A latent profile analysis identified an "inhibited" and "disinhibited" cluster based on personality traits. CONCLUSION: A wide range of symptoms persist after recovery and do not differ between subtypes of ED. These findings may aid in identifying traits that create vulnerabilities for developing an ED.

Adult↗

DSM-IV threshold versus subthreshold bulimia nervosa.

OBJECTIVE: The purpose of the present work is to determine whether bulimia nervosa (BN) and eating disorder not otherwise specified, BN type (EDNOS-BN) were qualitatively distinct in terms of eating and general psychopathology. METHOD: This study presents a comparison of 138 women with BN and 57 with EDNOS-BN from a multisite study on eating-related and general psychopathology measures. RESULTS: Although women with BN reported higher lifetime history rates of anorexia nervosa, greater binge eating and vomiting frequency, and more eating concerns, no significant differences were observed between groups on measures of perfectionism, impulsivity, obsessive-compulsiveness, anxiety, depressive symptomatology, or alcohol/substance problems. Based on the partial eta2 values, the distinction between BN and EDNOS-BN accounted for <5% of the criterion variance in general psychopathology measures. Post hoc analyses comparing EDNOS-BN with objective bulimic episodes (OBEs; n=34) versus no OBEs (n=23) found greater EDEQ-4 Restraint subscale scores for EDNOS-BN without OBEs. However, there was no significant difference on the EDEQ-4 Eating Concern subscale between the two EDNOS-BN subgroups. CONCLUSION: The findings highlight the clinical significance of BN partial syndrome and prompt reevaluation of existing BN diagnostic boundaries. Post hoc analyses also underscore the need for greater differentiation within EDNOS.

Adult↗

Performance of a weight-related measure of Quality of Life in a psychiatric sample.

The Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire has been validated previously in weight loss program participants and community volunteers. Because of the prevalence of obesity in individuals with schizophrenia and bipolar disorder, this study evaluates the psychometric performance of the IWQOL-Lite in these populations. A sample of 111 individuals with schizophrenia (mean age = 43.5; mean BMI = 32.6; 42.3% female; 59.5% Caucasian) and 100 with bipolar disorder (mean age = 42.8; mean BMI = 34.8; 66.0% female; 81.0% Caucasian) were recruited from four programs. Height and weight measurements were taken and participants completed the IWQOL-Lite, Medical Outcomes Study Short-Form-36 (SF-36), and Global Ratings of quality of life. Sixty-five participants completed the IWQOL-Lite 1-2 weeks later to determine stability of results. Sixty-four percent of schizophrenic participants and 68.0% of bipolar participants were obese. The IWQOL-Lite demonstrated excellent reliability in the current sample, with alpha coefficients ranging from 0.874 to 0.970 and test-retest coefficients ranging from 0.740 to 0.945. Correlations with collateral measures and BMI supported the construct validity of the IWQOL-Lite in this population. The IWQOL-Lite is a reliable and valid measure for assessing weight-related quality of life in individuals with schizophrenia and bipolar disorder.

Adult↗

Obesity and sexual quality of life.

OBJECTIVES: Reduced sexual quality of life is a frequently reported yet rarely studied consequence of obesity. The objectives of this study were to 1) examine the prevalence of sexual quality-of-life difficulties in obese individuals and 2) investigate the association between sexual quality of life and BMI class, sex, and obesity treatment-seeking status. RESEARCH METHODS AND PROCEDURES: Subjects consisted of 1) 500 participants in an intensive residential program for weight loss and lifestyle modification (BMI = 41.3 kg/m2), 2) 372 patients evaluated for gastric bypass surgery (BMI = 47.1 kg/m2), and 3) 286 obese control subjects not seeking weight loss treatment (BMI = 43.6 kg/m2). Participants completed the Impact of Weight on Quality of Life-Lite, a measure of weight-related quality of life. Responses to the four Sexual Life items (assessing enjoyment, desire, performance, and avoidance) were analyzed by BMI, sex, and group. RESULTS: Higher BMI was associated with greater impairments in sexual quality of life. Obese women reported more impairment in sexual quality of life than obese men for three of four items. Gastric bypass surgery candidates reported more impairment in sexual quality of life than residential patients and controls for most items. In general, residential patients reported levels of impairment greater than or equal to controls. DISCUSSION: Obesity is associated with lack of enjoyment of sexual activity, lack of sexual desire, difficulties with sexual performance, and avoidance of sexual encounters. Sexual quality of life is most impaired for women, individuals with Class III obesity, and patients seeking gastric bypass surgery.

Adolescent↗

Are U.S. women drinking less (or more)? Historical and aging trends, 1981-2001.

OBJECTIVE: Women's alcohol consumption in the United States has aroused increased public concern, despite a scarcity of evidence of any major increases in women's drinking. To help resolve this apparent inconsistency, we examined patterns of historical and age-related changes in U.S. women's drinking from 1981 to 2001. METHOD: In national surveys of women in 1981, 1991, and 2001, we measured the prevalence of 12-month and 30-day drinking, heavy episodic drinking (HED; six or more drinks per day), and subjective intoxication. Using these data, we analyzed time and age trends for six 10-year age groups in each survey, taking into account effects of repeated observations and possible covariates (ethnicity, marital status, and education). RESULTS: Women's 12-month drinking did not change significantly between 1981 and 1991, but it became more prevalent in the total samples between 1991 and 2001. Among 12-month drinkers, however, 30-day abstinence increased from 1981 to 2001 (particularly among women drinkers ages 21-30). From 1981 to 2001, HED declined (particularly among women drinkers ages 21-30), but intoxication became more prevalent (particularly among women drinkers ages 21-50). Drinking, HED, and intoxication became consistently less prevalent with increasing age. CONCLUSIONS: Among drinkers, increases in 30-day abstinence and declines in HED suggest that recent alarms about women's drinking may have been overstated. The contrast of lower rates of HED but increased reports of intoxication may indicate that women are more alert to alcohol's effects now than in earlier decades.

Adult↗

Impulsivity and compulsivity in bulimia nervosa.

OBJECTIVE: A primary objective of the current article is to investigate the relationship between impulsivity and compulsivity in patients with bulimia nervosa (BN). A second goal is to explore the relationship between impulsivity and compulsivity and related psychiatric problems. METHOD: Two-hundred four females with BN completed several measures of impulsivity and compulsivity as well as measures of personality, substance use, eating pathology, and depression. RESULTS: Participants reported considerable variability on measures of impulsivity and compulsivity and these scores were positively correlated with each other. Impulsive-compulsive groups differed in personality, substance use, eating, and depression. CONCLUSION: These findings suggest that impulsivity and compulsivity can coexist in BN patients and that both traits may provide useful information about comorbid problems in women with BN.

Adolescent↗

A study of patients with anorexia nervosa using ecologic momentary assessment.

OBJECTIVE: The purpose of the current study was to demonstrate the feasibility of studying subjects with anorexia nervosa (AN) using ecologic momentary assessment (EMA). A second goal of the current study was to conduct a preliminary investigation of a proposed model of anorexic behavior. METHOD: Ten female participants with AN carried Palm top computers for an average of 2 weeks per participant. Each day, participants were signaled six times by the Palm top and answered questions about mood, behavior, stressful events, and self-appraisal. RESULTS: AN subjects displayed excellent compliance with the protocol. Participants completed more than 90% of the signaled recordings. The results also generally support the model of AN behavior proposed. CONCLUSION: EMA appears to be a feasible and productive means of assessment in studying AN.

Adult↗