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Rui-Mao Zheng

Publications and source records attributed to Rui-Mao Zheng.

3 recordsLinked to original sources

Role of the central interleukin-1 in stress responses.

The molecules of interleukin-1 (IL-1) system are widely distributed in central nervous system. As a classical pro-inflammatory factor, central IL-1 has diverse biological functions and plays a pivotal role in a number of important physiological and pathophysiological processes. During the past few years, particular attentions have been directed to the stress mediator actions of central IL-1. This paper reviews some recent findings in the studies of central IL-1 functions in stress responses, including the effects of stress on central IL-1, the roles of IL-1 in the initiation of stress responses, the neural circuitries and intracellular signal transduction pathways involved in the central IL-1 mediated stress responses, as well as the actions of central IL-1 on brain high function and behavior under stressful conditions.

Journal Article↗

[Progress in central interleukin-1 system and its signaling pathway].

Central interleukin-1 (IL-1 ) system is a relatively independent system which is composed of IL-1 and other molecules associated with IL-1 in functions or structures. The knowledge of central IL-1 system in the constitution and function have been extended with the discovery of new members and its function, the extensive and intensive research on intracellular signaling pathways, as well as the relationship among those molecules. This paper reviews the recent findings in the study of central IL-1 system, which comprises the new members, new signaling molecules, new biological functions, and the effects in the processes of physiology and pathophysiology.

Animals↗